探讨老年高血糖危象的研究进展及展望
Exploring the Research Progress and Outlook of Hyperglycemic Crisis in the Elderly
摘要: 随着我国老龄化加剧,老年糖尿病发病率急剧上升。高血糖危象(Hyperglycemic crisis, HC)是糖尿病常见的急性并发症,严重影响患者预后。HC起病急,预后差,早诊治对改善患者预后极其重要。目前,各个指南对老年HC提出的诊断及治疗各有差异,为临床工作带来许多分歧。因此,本文对老年HC发病机制、诱因、诊断和治疗作一综述,对该疾病的救治诊疗进行总结。
Abstract: The incidence of diabetes mellitus in the elderly is increasing dramatically with the aging of China. Hyperglycemic crisis (HC) is a common acute complication of diabetes mellitus, which seriously af-fects the prognosis of patients. HC has a rapid onset and poor prognosis, and early diagnosis and treatment are extremely important to improve the prognosis of patients. At present, the diagnosis and treatment of HC in the elderly vary from guideline to guideline, which brings many differences in clinical work. Therefore, this article provides an overview of the pathogenesis, causative factors, diagnosis and treatment of HC in the elderly, and summarizes the life-saving diagnosis and treat-ment of this disease.
文章引用:买尔江古丽·阿布来克木, 薛洁, 靳瑾. 探讨老年高血糖危象的研究进展及展望[J]. 临床医学进展, 2023, 13(9): 13974-13979. https://doi.org/10.12677/ACM.2023.1391954

参考文献

[1] 任烨, 程海燕, 王霞娟, 等. 老年糖尿病酮症酸中毒病人的临床特征及预后分析[J]. 实用老年医学, 2022, 36(2): 168-172.
[2] Alshurtan, K., Alnizari, O., Aldarwish, H., et al. (2022) Efficacy and Safety of Intravenous Insulin in Treatment of Patient with Diabetic Ketoacidosis: A Systematic Review and Meta-Analysis. Cureus, 14, e30721. [Google Scholar] [CrossRef] [PubMed]
[3] 雷闽湘. 中高血糖危象[J]. 临床内科杂志, 2012, 29(9): 584-586.
[4] Baldrighi, M., Sainaghi, P., Bellan, M., et al. (2018) Hyperglycemic Hyperosmolar State: A Pragmatic Approach to Properly Manage Sodium Derangements. Current Diabetes Reviews, 14, 534-541. [Google Scholar] [CrossRef] [PubMed]
[5] Gebremedhin, G., Enqueselassie, F., Yifter, H., et al. (2021) Hyperglycemic Crisis Characteristics and Outcome of Care in Adult Patients without and with a History of Dia-betes in Tigrai, Ethiopia: Comparative Study. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 14, 547-556. [Google Scholar] [CrossRef
[6] Nkoke, C., Bain, L., Makoge, C., et al. (2021) Profile and Outcomes of Patients Admitted with Hyperglycemic Emergencies in the Buea Regional Hospital in Cameroon. The Pan African Medical Journal, 39, Article No. 274. [Google Scholar] [CrossRef] [PubMed]
[7] Aldhaeefi, M., Aldardeer, N.F., Alkhani, N., et al. (2021) Updates in the Management of Hyperglycemic Crisis. Frontiers in Clinical Diabetes and Healthcare, 2, Article ID: 820728. [Google Scholar] [CrossRef] [PubMed]
[8] Dhatariya, K. and Vellanki, P. (2017) Treatment of Dia-betic Ketoacidosis (DKA)/Hyperglycemic Hyperosmolar State (HHS): Novel Advances in the Management of Hyper-glycemic Crises (UK versus USA). Current Diabetes Reports, 17, Article No. 33. [Google Scholar] [CrossRef] [PubMed]
[9] Gaglia, J., Wyckoff, J. and Abrahamson, M. (2004) Acute Hy-perglycemic Crisis in the Elderly. The Medical Clinics of North America, 88, 1063-1084, xii. [Google Scholar] [CrossRef] [PubMed]
[10] Sproston, N. and Ashworth, J. (2018) Role of C-Reactive Protein at Sites of Inflammation and Infection. Frontiers in Immunology, 9, Article No. 754. [Google Scholar] [CrossRef] [PubMed]
[11] Hassan, E.M., Mushtaq, H., Mahmoud, E.E., et al. (2022) Overlap of Diabetic Ketoacidosis and Hyperosmolar Hyperglycemic State. World Journal of Clinical Cases, 10, 11702-11711. [Google Scholar] [CrossRef] [PubMed]
[12] 段紫潇, 郭雪雯, 杨刚毅, 等. 成人高血糖危象的诊治现状及展望[J]. 中华糖尿病杂志, 2022, 14(10): 1011-1016.
[13] 许丹, 张晋, 杨琴, 等. 糖尿病高血糖危象患者合并败血症的临床分析[J]. 四川医学, 2017, 38(2): 169-173.
[14] Corwell, B., Knight, B., Olivieri, L., et al. (2014) Cur-rent Diagnosis and Treatment of Hyperglycemic Emergencies. Emergency Medicine Clinics of North America, 32, 437-452. [Google Scholar] [CrossRef] [PubMed]
[15] Cruz-Flores, S. (2021) Neurological Complications of Endocrine Emergencies. Current Neurology and Neuroscience Reports, 21, Article No. 21. [Google Scholar] [CrossRef] [PubMed]
[16] Gosmanov, A., Gosmanova, E. and Dillard-Cannon, E. (2014) Management of Adult Diabetic Ketoacidosis. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 7, 255-264. [Google Scholar] [CrossRef
[17] Steenkamp, D., Alexanian, S. and Mcdonnell, M. (2013) Adult Hyperglycemic Crisis: A Review and Perspective. Current Diabetes Reports, 13, 130-137. [Google Scholar] [CrossRef] [PubMed]
[18] Kearney, T. and Dang, C. (2007) Diabetic and Endocrine Emer-gencies. Postgraduate Medical Journal, 83, 79-86. [Google Scholar] [CrossRef] [PubMed]
[19] Evans, K. (2019) Diabetic Ketoacidosis: Update on Management. Clinical Medicine (London), 19, 396-398. [Google Scholar] [CrossRef] [PubMed]
[20] Okada, A., Yamana, H., Morita, K., et al. (2021) Potassium Con-centration in Initial Fluid Therapy and In-Hospital Mortality of Patients with Diabetic Ketoacidosis. The Journal of Clini-cal Endocrinology and Metabolism, 106, e2162-e2175. [Google Scholar] [CrossRef] [PubMed]