正常甲状腺病态综合征与急性心肌梗死的相关性研究进展

Research Progress on the Correlation between Euthyroid Sick Syndrome and Acute Myocardial Infarction

摘要: 随着社会经济的迅速发展、人民生活水平的提高以及生活节奏的加快，我国心血管疾病发生率仍然呈增高趋势，尤其是急性心肌梗死，且其多发人群呈逐年年轻化趋势，尽管近年来药物治疗和心肌再灌注程序取得了很大的进展，但急性心肌梗死的短期和长期死亡率仍居高不下，正常甲状腺病态综合征是指无明显甲状腺疾病的情况下出现的甲状腺激素水平异常，在急性心肌梗死患者中常见，近年来多项研究表明正常甲状腺病态综合征严重影响急性心肌梗死的严重程度，且其甲状腺激素浓度的改变可作为急性心肌梗死病情严重程度及不良预后的强有力的预测因子。本文将对正常甲状腺病态综合征的概念、发病机制及其与急性心肌梗死的相关性等进行综述。

Abstract: With the rapid development of social economy, the improvement of people’s living standards and the acceleration of the pace of life, the incidence of cardiovascular diseases in China is still increas-ing, especially acute myocardial infarction, and its prone population is becoming younger year by year, although drug therapy and myocardial reperfusion procedures have made great progress in recent years. However, the short-term and long-term mortality of acute myocardial infarction is still high. Euthyroid sick syndrome refers to abnormal thyroid hormone levels in the absence of obvious thyroid disease, which is common in patients with acute myocardial infarction. In recent years, a number of studies have shown that euthyroid sick syndrome seriously affects the severity of acute myocardial infarction. The change of thyroid hormone concentration can be used as a powerful pre-dictor of acute myocardial infarction severity and poor prognosis. This article will review the con-cept, pathogenesis and correlation between euthyroid sick syndrome and acute myocardial infarc-tion.