糖尿病视网膜病变早期及PRP前后对视功能检测的研究进展
Advances in Early Diabetic Retinopathy and before and after PRP on Visual Function Detection
DOI: 10.12677/ACM.2023.1392086, PDF,    科研立项经费支持
作者: 范清琳：山东第一医科大学(山东省医学科学院)研究生部，山东 济南；伦英俊, 邰仁清, 侯梦铃：潍坊医学院研究生部，山东 潍坊；高宏程, 陈 晨*：临沂市人民医院眼科，山东 临沂
关键词: 糖尿病视网膜病变；激光光凝；视网膜功能；综述；Diabetic Retinopathy； Panretinal Photocoagulation； Retinal Function； Review
摘要: 糖尿病性视网膜病变(diabetic retinopathy, DR)是最常见的视网膜血管疾病，是导致糖尿病人群视力丧失的主要原因。而且随着研究进展，DR不单纯是视网膜微血管异常的病变，其还伴随视网膜神经退行性异常改变。目前临床上按DR发展阶段和严重程度，将其分为无明显视网膜病变(non-obvious diabetic retinopathy, NDR)、非增殖型糖尿病视网膜病变(nonproliferative diabetic retinopathy, NPDR)和增殖型糖尿病性视网膜病变(proliferative diabetic retinopathy, PDR)。DR由于其复杂的病理变化早期即破坏了视网膜正常的功能，因而及时、安全、有效地对重度NPDR和PDR患者行全视网膜激光光凝治疗(panretinal photocoagulation, PRP)显得极其重要。近年来光学相干断层扫描技术(optical coherence tomography, OCT)、多焦视网膜电图(multifocal electroretinograms, mfERG)、眼底视野计(Fundus Perimetry)、图形视觉诱发电位(pattern reversal visual evoked potentioals, P-VEP)作为眼科常用的检查技术，在早期监测视网膜功能的异常及PRP术后视网膜功能进展变化的追踪评估中得到了广泛的应用，对DR诊断、治疗和后期疗效评估提供一定的参考价值。本文就近年来DR患者早期及PRP前后有关视功能检测方法的研究进展做一综述。
Abstract: Diabetic retinopathy (DR) is the most common retinal vascular disease and is the leading cause of vision loss in the diabetic population. With the advancement of research, DR is not only a lesion of retinal microvascular abnormalities, but also accompanied by abnormal retinal neurodegenerative changes. Currently, DR is classified into non-obvious diabetic retinopathy (NDR), non-proli- ferative diabetic retinopathy (NPDR) and proliferative diabetic retinopathy (PDR) according to the stage of development and severity of DR. Because of the complex pathological changes that disrupt the normal function of the retina at an early stage, the importance of the timely, safe and effective panretinal photocoagulation (PRP) for patients with severe NPDR and PDR is paramount. In recent years, optical coherence tomography (OCT), multifocal electroretinograms (mfERG), fundus perim-etry, pattern reversal visual evoked potentiation (P-VEP), are commonly used in ophthalmology to monitor the abnormalities of retinal function at an early stage and to follow up the changes of reti-nal function after PRP, which provide a certain reference value for the diagnosis, treatment and lat-er efficacy assessment of DR. In this paper, we review the progress of research on visual function testing methods in DR patients in the early stage and before and after PRP.
文章引用：范清琳, 伦英俊, 邰仁清, 侯梦铃, 高宏程, 陈晨. 糖尿病视网膜病变早期及PRP前后对视功能检测的研究进展[J]. 临床医学进展, 2023, 13(9): 14908-14916. https://doi.org/10.12677/ACM.2023.1392086

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