脓毒症致急性肾损伤与微循环障碍的关系研究
Relationship between Acute Renal Injury In-duced by Sepsis and Microcirculation Disturbance
摘要: 急性肾损伤发生最常见的原因是脓毒症，脓毒症导致肾脏微循环的改变是脓毒症相关急性肾损伤的主要原因，脓毒症通过炎症反应、球管失衡和血流重分布来影响肾脏微循环，进而导致肾小管坏死，针对病因出现了抗炎、液体复苏和血流重分布的治疗措施。本文旨在研究SA-AKI发生的机制，从而预防脓毒症患者进一步损伤肾脏及减低脓毒症患者死亡率，现就近年研究进展做一综述。
Abstract: Sepsis is the most common cause of acute kidney injury, and the change of renal microcirculation caused by sepsis is the main cause of sepsis-associated acute kidney injury, sepsis affects renal mi-crocirculation through inflammatory reaction, imbalance of bulbar duct and redistribution of blood flow, which leads to tubular necrosis. Anti-inflammatory, fluid resuscitation and redistribution of blood flow have been suggested to treat sepsis. This article aims to study the mechanism of SA-AKI, so as to prevent further renal damage and reduce mortality in patients with sepsis.
文章引用：胡洁, 罗朋立. 脓毒症致急性肾损伤与微循环障碍的关系研究[J]. 临床医学进展, 2023, 13(10): 15308-15313. https://doi.org/10.12677/ACM.2023.13102142

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