18F-FDG-PET/CT与99mTc-MDP对乳腺癌患者骨转移诊断价值的比较
18F-FDG-PET/CT and 99mTc-MDP for Bone Metastasis in Breast Cancer Patients Comparison of Diagnostic Values
DOI: 10.12677/ACM.2023.13102153, PDF,   
作者: 尹健健, 赵化荣：新疆医科大学第一附属医院肿瘤中心，新疆 乌鲁木齐
关键词: 乳腺癌；骨转移；18F-FDG-PET/CT；99mTc-MDP；Breast Cancer； Bone Metastases； 18F-FDG-PET/CT； 99mTc-MDP
摘要: 乳腺癌是目前全世界女性中发病率位居首位的恶性肿瘤，及早地监测并诊断乳腺癌患者有无骨转移的发生和骨转移的程度，对乳腺癌患者病情的分期、再分期、术前制定治疗方案以及预后评估有着十分重要的价值。目前，应用18F-FDG-PET/CT对乳腺癌患者骨转移进行诊断的临床价值受到众多关注，但其相较于99mTc-MDP对乳腺癌患者骨转移诊断价值的优点和不足仍需要进一步研究。本文通过多种常用的数据库检索文献，收集整理大量近年来国内外将18F-FDG-PET/CT与99mTc-MDP用于乳腺癌患者骨转移临床诊断的相关文献，通过比较二者在乳腺癌骨转移诊断过程中的精准度、灵敏度及是否便捷无创等因素，对18F-FDG-PET/CT与99mTc-MDP在临床研究中实际诊断的应用价值的优缺点进行评价开展综述，为乳腺癌骨转移患者的临床精准诊断提供参考。
Abstract: Breast cancer is currently the most malignant tumor among women in the world, and early moni-toring and diagnosis of the occurrence of bone metastases and the degree of bone metastasis in breast cancer patients are of great value for the staging, restaging, preoperative treatment plan and prognosis assessment of breast cancer patients. At present, the clinical value of the use of 18F-FDG-PET/CT to diagnose bone metastasis in breast cancer patients has attracted much attention, but its advantages and disadvantages in the diagnosis of bone metastasis in breast cancer patients compared with 99mTc-MDP still need further research. In this paper, through a variety of commonly used databases to consult the literature, collect and sort out a large number of domestic and foreign 18F-FDG-PET/CT and 99mTc-MDP for the clinical diagnosis of bone metastasis in breast cancer pa-tients in recent years, by comparing the accuracy, sensitivity and convenience and non-invasiveness of the two in the diagnosis of breast cancer bone metastasis, the advantages and disadvantages of the application value of 18F-FDG-PET/CT and 99mTc-MDP in clinical research are evaluated and re-viewed. It provides a reference for the clinical and accurate diagnosis of patients with breast cancer bone metastases.
文章引用：尹健健, 赵化荣. 18F-FDG-PET/CT与99mTc-MDP对乳腺癌患者骨转移诊断价值的比较[J]. 临床医学进展, 2023, 13(10): 15390-15396. https://doi.org/10.12677/ACM.2023.13102153

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