ICU镇静药物新进展——注射用甲磺酸瑞马唑仑
New Progress of Sedatives in ICU—Remimazolam Mesylate for Injection
DOI: 10.12677/ACM.2023.13102166, PDF,   
作者: 姜 杉：大连医科大学研究生院，辽宁 大连
关键词: 瑞马唑仑；镇静药；ICU；不良反应；Remimazolam； Sedative； ICU； Adverse Effect
摘要: 瑞马唑仑是新型苯二氮卓类药物，具有超效性、水溶性，通过非特异性酯酶快速代谢，代谢物几乎不具备药理活性，可被氟马西尼快速逆转，镇静成功率高，镇静深度可调控，低血压等不良反应少，且可抑制细胞因子分泌和通过调节细胞增殖来影响免疫细胞功能。
Abstract: Remimazolam is a new benzadverse effectdiazepine drug, which is super-effective and wa-ter-soluble. It is rapidly metabolized by non-specific esterase, and its metabolites have almost no pharmacological activity. It can be quickly reversed by Masini fluoride, with high sedation success rate, adjustable sedation depth and few adverse reactions such as hypotension, and can inhibit cy-tokine secretion and affect immune cell function by regulating cell proliferation.
文章引用：姜杉. ICU镇静药物新进展——注射用甲磺酸瑞马唑仑[J]. 临床医学进展, 2023, 13(10): 15484-15488. https://doi.org/10.12677/ACM.2023.13102166

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