磁共振在食管癌诊疗过程中的应用进展
Progress in the Application of Magnetic Resonance in the Diagnosis and Treatment of Esophageal Cancer
DOI: 10.12677/ACM.2023.13102175, PDF,   
作者: 张石峰：新疆医科大学第三临床医学院/附属肿瘤医院，新疆 乌鲁木齐；徐 慧*：新疆医科大学附属肿瘤医院影像诊断中心，新疆 乌鲁木齐
关键词: 食管癌；MRI；病理分期；疗效评估；Esophageal Cancer； MRI； Pathological Stage； Efficacy Evaluation
摘要: 食管癌是一种全球性的上消化道恶性肿瘤，在全球高发癌症中排名第八，死亡率也位居前列。食管癌的治疗是一个系统性的治疗，其中治疗方案的选择、疗效评价依赖于早期诊断、术前分期及术前可切除性评估。现如今影像学已经成为食管癌诊断和评估疗效的重要手段，随着MRI技术的发展，其已成为食管癌诊疗过程中的重要手段，本文将对磁共振在食管癌诊疗过程中的应用进展进行综述，以期为临床提供有效的指导与建议。
Abstract: Esophageal cancer is a global malignancy of the upper digestive tract, ranking eighth among the most common cancers in the world, with one of the highest mortality rates. The treatment of esophageal cancer is a systematic treatment, in which the choice of treatment and the expectation of curative effect depend on early diagnosis, preoperative staging and preoperative resectable evaluation. Nowadays, imaging has become an important means to diagnose and evaluate the cura-tive effect of esophageal cancer. With the development of MRI technology, it has become an im-portant means in the diagnosis and treatment of esophageal cancer. This paper will review the ap-plication progress of magnetic resonance in the diagnosis and treatment of esophageal cancer, in order to provide effective guidance and suggestions for clinical practice.
文章引用：张石峰, 徐慧. 磁共振在食管癌诊疗过程中的应用进展[J]. 临床医学进展, 2023, 13(10): 15547-15554. https://doi.org/10.12677/ACM.2023.13102175

参考文献

[1] Abnet, C.C., Arnold, M. and Wei, W.Q. (2018) Epidemiology of Esophageal Squamous Cell Carcinoma. Gastroenter-ology, 154, 360-373. [Google Scholar] [CrossRef] [PubMed]
[2] Sung, H., Ferlay, J., Siegel, R.L., et al. (2021) Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA: A Cancer Journal for Clinicians, 71, 209-249. [Google Scholar] [CrossRef] [PubMed]
[3] Rustgi, A.K. and El-Serag, H.B. (2014) Esophageal Carcinoma. The New England Journal of Medicine, 371, 2499- 2509. [Google Scholar] [CrossRef] 
[4] Chen, W.-S., Yang, S.-J., Ping, W., et al. (2015) CYP2J2 and EETs Protect against Lung Ischemia/Reperfusion Injury via Anti-Inflammatory Effects in Vivo and in Vitro. Cellular Physiology and Biochemistry, 35, 2043-2054. [Google Scholar] [CrossRef] [PubMed]
[5] Okaruao, R.A., Farah, A., et al. (2018) Comparative Oesophageal Cancer Risk Assessment of Hot Beverage Consumption (Coffee, Mate and Tea): The Margin of Exposure of PAH vs Very Hot Temperatures. BMC Cancer, 18, Article No. 236. [Google Scholar] [CrossRef] [PubMed]
[6] Palacio, D., Marom, E.M., Correa, A., et al. (2018) Diagnosing Conduit Leak after Esophagectomy for Esophageal Cancer by Com-puted Tomography Leak Protocol and Standard Esophagram: Is Old School Still the Best. Clinical Imaging, 51, 23-29. [Google Scholar] [CrossRef] [PubMed]
[7] Tangokua, Y., Furukita, Y., et al. (2012) The New Era of Staging as a Key for an Appropriate Treatment for Esophageal Cancer. Annals of Thoracic and Cardiovascular Surgery, 18, 190-199. [Google Scholar] [CrossRef] [PubMed]
[8] Hong, S.J., Kim, T.J., Nan, K.B., et al. (2014) New TNM Staging System for Esophageal Cancer: What Chest Radiologists Need to Know. Radiographics, 34, 1722-1740. [Google Scholar] [CrossRef] [PubMed]
[9] Tan, X., Ma, Z., Yan, L., et al. (2019) Radiomics Nomogram Outper-forms Size Criteria in Discriminating Lymph Node Metastasis in Resectable Esophageal Squamous Cell Carcinoma. Eu-ropean Radiology, 29, 392-400. [Google Scholar] [CrossRef] [PubMed]
[10] Cheung, G.S.M. (2013) Contribution of PET-CT in Radiotherapy Planning of Oesophageal Carcinoma: A Review. Radiography, 19, 259-269. [Google Scholar] [CrossRef] 
[11] 彭雄, 陈云, 等. 微创McKeown食管癌根治术与Ivor-Lewis手术治疗食管癌的近期疗效对比[J]. 中南大学学报 (医学版), 2017, 42(5): 546-552.
[12] Yamada, I., Miyasaka, N., Hikishima, K., et al. (2015) Ultra-High-Resolution MR Imaging of Esophageal Carcinoma at Ultra-High Field Strength (7.0T) ex Vivo: Correlation with Histopathologic Findings. Magnetic Resonance Imaging, 33, 413-419. [Google Scholar] [CrossRef] [PubMed]
[13] Riddell, A.M., Hillier, J., Brown, G., et al. (2006) Potential of Sur-face-Coil MRI for Staging of Esophageal Cancer. American Journal of Roentgenology, 187, 1280-1287. [Google Scholar] [CrossRef] 
[14] Baliyan, V., Das, C.J., Sharma, R., et al. (2016) Diffusion Weighted Imaging: Technique and Applications. World Journal of Radiology, 8, 785-798. [Google Scholar] [CrossRef] [PubMed]
[15] 陈伟, 周胜利. DWI在食管癌定量及定期诊断中的价值[J]. 临床放射学杂志, 2014, 33(3): 388-393.
[16] 孙静, 王铸. ADC值对食管癌T分期及病理分级的诊断价值[J]. 磁共振成像, 2020, 11(7): 531-534.
[17] 孟方方. 高场强MRI对食管癌T分期的诊断价值[D]: [硕士学位论文]. 郑州: 郑州大学, 2013.
[18] 李炳荣, 张坤, 严小斌, 等. 2018版 MRI肝脏影像报告和数据系统对≤3 cm肝细胞癌与其他肝脏原发恶性肿瘤的鉴别诊断价值[J]. 中华放射学杂志, 2021, 55(2): 166-172.
[19] 蒋春峰. BLADE技术在上腹部自由呼吸导航T2WI中的应用价值[J]. 世界复合医学, 2022, 8(2): 80-82+86.
[20] 林生发. MRI多模态新序列对比MDCT在食管癌T分期效能的研究[D]: [硕士学位论文]. 福州: 福建医科大学, 2020.[CrossRef] 
[21] Chandarana, H., Block, T.K., Rosenkrantz, A.B., et al. (2011) Free-Breathing Radial 3D Fat Suppressed T1-Weighted Gradient Echo Sequence: A Viable Alternative for Con-trast Enhanced Liver Imaging in Patients Unable to Suspend Respiration. Investigative Radiology, 46, 648-653. [Google Scholar] [CrossRef] 
[22] 张风光, 张宏凯, 李祥, 等. 伪影校正技术联合自由呼吸放射状K空间填充方式的容积内插体部检查对可切除性食管癌术前T分期的价值[J]. 中华放射学杂志, 2017, 51(2): 114-118.
[23] Azevedo, R.M., de Campos, R.O., Ramalho, M., et al. (2011) Free -Breathing 3D T1-Weighted Gradient-Echo Sequence with Radial Data Sampling in Abdominal MRI: Preliminary Observations. American Journal of Roentgenology, 197, 650-657. [Google Scholar] [CrossRef] 
[24] 王昭琦, 张风光, 郭佳, 等. 高场磁共振对可切除性食管癌术前T分期的可行性分析[J]. 中华医学杂志, 2017, 97(11): 843-846.
[25] Melis, M., Masi, A., Pinna, A., et al. (2015) Does Lymph Node Ratio Affect Prognosis in Gastroesophageal Cancer? The American Journal of Surgery, 210, 443-450. [Google Scholar] [CrossRef] [PubMed]
[26] Alper, F., Turkyilmaz, A., Kurtcan, S., et al. (2011) Effectiveness of the STIR Turbo Spin-Echo Sequence MR Imaging in Evaluation of Lymphad-enopathy in Esophageal Cancer. European Journal of Radiology, 80, 625-628. [Google Scholar] [CrossRef] [PubMed]
[27] Shuto, K., Kono, T., Shiratori, T., et al. (2020) Diagnostic Perfor-mance of Diffusion-Weighted Magnetic Resonance Imaging in Assessing Lymph Node Metastasis of Esophageal Cancer Compared with PET. Esophagus, 17, 239-249. [Google Scholar] [CrossRef] [PubMed]
[28] Triantafyllou, M., Studer, U.E., Birkhäuser, F.D., et al. (2013) Ultrasmall Superparamagnetic Particles of Iron Oxide Allow for the Detection of Metastases in Normal Sized Pelvic Lymph Nodes of Patients with Bladder and/or Prostate Cancer. European Journal of Cancer, 49, 616-624. [Google Scholar] [CrossRef] [PubMed]
[29] Zhang, F., Zhu, L., Huang, X., Niu, G. and Chen, X. (2013) Dif-ferentiation of Reactive and Tumor Metastatic Lymph Nodes with Diffusion-Weighted and SPIO-Enhanced MRI. Molec-ular Imaging and Biology, 15, 40-47. [Google Scholar] [CrossRef] [PubMed]
[30] Varghese, K.T., Hofstetter, L.W., Rizk, P.N., et al. (2013) The Society of Thoracic Surgeons Guidelines on the Diagnosis and Staging of Patients with Esophageal Cancer. The Annals of Thoracic Surgery, 96, 346-356. [Google Scholar] [CrossRef] [PubMed]
[31] Cafagna, D., Rubini, G., Luele, F., et al. (2012) Whole-Body MRDWIBS vs. [18F]-FDG-PET/CT in the Study of Malignant Tumors: A Retrospective Study. Radiologia Medica, 117, 293-311. [Google Scholar] [CrossRef] [PubMed]
[32] Wang, N.F., Zhang, M.J., Sun, T., et al. (2012) A Comparative Study: Diffusion Weighted Whole Body Imaging with Background Body Signal Suppression and Hybrid Positron Emission Computed Tomography on Detecting Lesions in Oncologic Clinics. European Journal of Radiology, 81, 1662-1666. [Google Scholar] [CrossRef] [PubMed]
[33] Sillah, K., Williams, L.R., Laasch, H.U., et al. (2010) Computed Tomography Overestimation of Esophageal Tumor Length: Implications for Radiotherapy Planning. World Journal of Gastrointestinal Oncology, 2, 197-204. [Google Scholar] [CrossRef] [PubMed]
[34] Hou, D.L., Shi, G.F., Gao, X.S., et al. (2013) Improved Longitudinal Length Accuracy of Gross Tumor Volume Delineation with Diffusion Weighted Magnetic Resonance Imaging for Esophageal Squamous Cell Carcinoma. Radiation Oncology, 8, Article No. 169. [Google Scholar] [CrossRef] 
[35] 李胜业, 杨华. MRI影像与CT影像融合探讨技术在局部晚期食管癌放疗靶区勾画中的应用效果[J]. 影像研究与医学应用, 2021, 5(17): 76-77.
[36] 张宇琳, 吴涛, 刘鸿翔, 等. 手术联合新辅助化疗对局部晚期食管癌患者的疗效及生存时间研究[J]. 肿瘤药学, 2017, 7(3): 300-303.
[37] Heethuis, S.E., van Rossum, P.S., Lips, I.M., et al. (2016) Dynamic Contrast-Enhanced MRI for Treat-ment Response Assessment in Patients with Oesophageal Cancer Receiving Neoadjuvant Chemoradiotherapy. Radio-therapy and Oncology, 120, 128-135. [Google Scholar] [CrossRef] [PubMed]
[38] Lei, J., Han, Q., Zhu, S., et al. (2015) Assessment of Esophageal Carcinoma Undergoing Concurrent Chemoradiotherapy with Quantitative Dy-namic Contrast-Enhanced Magnetic Resonance Imaging. Oncology Letters, 10, 3607-3612. [Google Scholar] [CrossRef] [PubMed]
[39] Liu, C., Sun, R., Wang, J., Ning, F., Wang, Z., Luo, J., Chen, S. and Yuan, S. (2020) Combination of DCE-MRI and DWI in Predicting the Treatment Effect of Concurrent Chemoradiother-apy in Esophageal Carcinoma. BioMed Research International, 2020, Article ID: 2576563. [Google Scholar] [CrossRef] [PubMed]
[40] Vollenbrock, S.E., Voncken, F.E.M., van Dieren, J.M., et al. (2019) Diagnostic Performance of MRI for Assessment of Response to Neoadjuvant Chemoradiotherapy in Oesophageal Can-cer. British Journal of Surgery, 106, 596-605. [Google Scholar] [CrossRef] [PubMed]
[41] Heethuis, S.E., Goense, L., Van Rossum, P.S.N., et al. (2018) DWI-MRI and DCE-MRI Are of Complementary Value in Predicting Pathologic Response to Neoadjuvant Chemoradiotherapy for Esophageal Cancer. Acta Oncologica, 57, 1201-1208. [Google Scholar] [CrossRef] 
[42] 张文宝, 杨清波, 吴双飞, 等. 磁共振扩散加权成像在食管癌放化疗疗效评估中的应用[J]. 中华医学杂志, 2021, 101(41): 3427-3430.
[43] 马秀梅, 席俊峰, 张世达. 食管癌磁共振成像表现与微血管密度和预后的关系[J]. 中国肿瘤临床与康复, 2021, 28(11): 1345-1348.
[44] 陈美玲, 刘儒鹏, 冯婷婷, 康小红, 李宁, 田新学. DCE-MRI联合DWI技术对食管癌患者放疗疗效的评估分析[J]. 实用癌症杂志, 2022, 37(8): 1296-1299.

为你推荐