微小RNA在心房颤动中的研究进展
Research Progress of MicroRNA in Atrial Fibrillation
DOI: 10.12677/ACM.2023.13102181, PDF,   
作者: 阿尔祖古丽·麦麦提, 麦五久代·吐尔逊, 阿比旦·尼加提：新疆医科大学研究生院，新疆 乌鲁木齐；冯 艳*：新疆维吾尔自治区人民医院心电学科，新疆 乌鲁木齐
关键词: 心房颤动；miRNA；重构；Atrial Fibrillation； miRNA； Remodeling
摘要: 微小RNA (miRNA)是一种小的非编码RNA，参与调控转录后基因表达。近年来miRNA在心房颤动中的调控作用成为研究热点。miRNA广泛参与心房电重构、结构重构和神经重构。根据现有研究，参与电重构的miRNA主要包括miRNA-1、miRNA-328、miRNA-499、miRNA-208、miRNA-26；参与结构重构的miRNA主要包括miRNA-21、miRNA-29、miRNA-133、miRNA-26；参与神经重构的miRNA主要包括miRNA-30、miRNA-206等。深入研究miRNA与心房重构的相关性，为心房颤动的诊疗提供新的思路。
Abstract: MicroRNA (miRNA) is a small non-coding RNA, which is involved in the regulation of post-tran- scriptional gene expression. In recent years, the regulatory role of miRNA in atrial fibrillation has become a research hotspot. miRNAs is widely involved in atrial electrical remodeling, structural remodeling and neural remodeling. According to the existing research, miRNAs involved in electri-cal reconfiguration mainly include miRNA-1, miRNA-328, miRNA-499, miRNA-208 and miRNA-26; miRNAs involved in structural reconstruction mainly include miRNA-133, miRNA-21, miRNA-29, miRNA-26 and miRNA-208; miRNAs involved in neural remodeling mainly includes miRNA-30 and miRNA-206. In-depth study on the correlation between miRNA and atrial remodeling provides new ideas for the diagnosis and treatment of atrial fibrillation.
文章引用：阿尔祖古丽·麦麦提, 麦五久代·吐尔逊, 阿比旦·尼加提, 冯艳. 微小RNA在心房颤动中的研究进展[J]. 临床医学进展, 2023, 13(10): 15593-15599. https://doi.org/10.12677/ACM.2023.13102181

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