PI3K/AKT信号通路在支气管哮喘的研究进展及中医药干预现状
Research Progress of PI3K/AKT Signaling Pathway in Bronchial Asthma and Status of Traditional Chinese Medicine Intervention
DOI: 10.12677/TCM.2023.1210423, PDF,  被引量   
作者: 蔡丽鑫：黑龙江中医药大学研究生院，黑龙江 哈尔滨
关键词: 支气管哮喘；PI3K/AKT信号通路；中医药；Bronchial Asthma； PI3K/AKT Signaling Pathway； Traditional Chinese Medicine
摘要: 支气管哮喘是一种反复发作的慢性气道炎症反应，研究表明PI3K/AKT信号通路在哮喘的发生、发展过程中起着重要的作用。本文通过查阅文献，从PI3K/AKT通路的构成、激活，与T淋巴细胞群比例失衡、炎症反应、气道重塑和氧化应激等造成哮喘的机制之间的关系，以及中医药干预PI3K/AKT信号通路治疗哮喘进行论述，以期能为支气管哮喘的临床研究和治疗提供参考。
Abstract: Bronchial asthma is a recurrent chronic airway inflammatory response. Studies have shown that PI3K/AKT signaling pathway plays an important role in the occurrence and development of asthma. Through literature review, this paper discusses the relationship between the composition and acti-vation of PI3K/AKT pathway and the mechanism of asthma caused by imbalance of T lymphocyte population, inflammatory response, airway remodeling and oxidative stress, as well as the inter-vention of traditional Chinese medicine in PI3K/AKT signaling pathway in the treatment of asthma, in order to provide reference for clinical research and treatment of bronchial asthma.
文章引用：蔡丽鑫. PI3K/AKT信号通路在支气管哮喘的研究进展及中医药干预现状[J]. 中医学, 2023, 12(10): 2819-2825. https://doi.org/10.12677/TCM.2023.1210423

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