物理与药物干预体温保护在围手术期体温管理的应用进展

Research Progress of Body Temperature Protection with Physical and Pharmacological Intervention in Perioperative Temperature Management

摘要: 围手术期发生低体温率高，这与术后多种不良并发症密切相关，不利于术后康复。因此体温保护受到额外的关注，同时也被列入到麻醉质控指标之一。当前，对围手术期低体温，又称围手术期意外低体温(perioperative inadvertent hypothermia, IPH)防治的主要方法是物理被动预防措施，来隔离热量的散失，而主动预防措施则是通过增加额外的热量，来实现体内产热与散热的平衡。缺乏从低体温发生机制出发，药物干预减少核心温度再分布，增加产热维度来体温保护研究。本文分析前期研究成果，从围手术期低体温新概述，物理体温保护，多维度药物干预体温保护展开综述，为围手术麻醉期实施有效保温策略提供参考。

Abstract: The incidence of perioperative hypothermia was high, and this is more closely related to many ad-verse complications, which is not conducive to postoperative rehabilitation. Therefore, temperature protection receives additional attention and is also included as one of the quality control indicators of anesthesia. Currently, perioperative inadvertent hypothermia (IPH) is primarily prevented by physical passive prophylaxis to isolate heat loss, and active prophylaxis by adding additional heat to achieve a balance between heat production and heat dissipation in the body. Lacking of the studies of body temperature protection, which starts from the mechanism of hypotermia, such as pharma-cological intervention to reduce core temperature and increasing the heat production. This paper analyzed the previoPhysical insulations research results, and summarized the new overview of perioperative hypothermia, physical body temperature protection, and multi-dimensional drug in-tervention body temperature protection, so as to provide reference for the implementation of effec-tive insulation strategies during perioperative anesthesia.