ANGPTL7与阻塞性睡眠呼吸暂停低通气综合征相关性的研究进展
Research Progress on the Correlation between ANGPTL7 and Obstructive Sleep Apnea Hypopnea Syndrome
DOI: 10.12677/ACM.2023.13102320, PDF,    科研立项经费支持
作者: 瞿道群*, 吴国飘：华北理工大学研究生学院，河北 唐山；河北省人民医院老年呼吸内科，河北 石家庄；平 芬#, 周智明：河北省人民医院老年呼吸内科，河北 石家庄
关键词: 阻塞性睡眠呼吸暂停低通气综合征；血管生成素样因子-7 (ANGPTL7)；生物标志物；Obstructive Sleep Apnea Hypopnea Syndrome； Angiopoietin-Like Proteins 7 (ANGPTL7)； Biomarker
摘要: 阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopnea syndrome, OSAHS)是临床常见的潜在致死性睡眠呼吸性疾病，可造成全身多器官损害，与心血管疾病、高血压、糖尿病及肿瘤等疾病密切相关。血管生成素样因子-7 (angiopoietin-like proteins 7, ANGPTL7)可以调控血管生成，在炎症反应、内皮细胞损伤、糖脂代谢紊乱中均有重要作用，也能干预肥胖的形成，可能与OSAHS的发生发展存在联系。本文就OSAHS与ANGPTL7二者之间的联系作一综述。
Abstract: Obstructive sleep apnea hypopnea syndrome (OSAHS) is a common and potentially fatal sleep res-piratory disease, which can cause systemic multiple organ damage and is closely related to cardio-vascular disease, hypertension, diabetes and cancer. Angiopoietin-like proteins 7 (ANGPTL7) can regulate angiogenesis, play an important role in inflammatory response, endothelial cell injury, glucose and lipid metabolism disorders, and can also intervene in the formation of obesity, which may be related to the occurrence and development of OSAHS. This article reviews the relationship between OSAHS and ANGPTL7.
文章引用：瞿道群, 平芬, 周智明, 吴国飘. ANGPTL7与阻塞性睡眠呼吸暂停低通气综合征相关性的研究进展[J]. 临床医学进展, 2023, 13(10): 16577-16583. https://doi.org/10.12677/ACM.2023.13102320

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