椎–基底动脉扩张延长症的血管内诊治研究进展
Research Progress in Endovascular Diagnosis and Treatment of Vertebrobasilar Dolichoectasia
DOI: 10.12677/ACM.2023.13102332, PDF,   
作者: 董俊君*：广东医科大学第一临床医学院，广东 湛江；郑 勇#：深圳大学附属第二医院(宝安区人民医院)，广东 深圳
关键词: 椎–基底动脉扩张延长症；颅神经；基底动脉；脑卒中；Vertebrobasilar Dolichoectasia； Cranial Nerves； Basilar Artery； Stroke
摘要: 椎–基底动脉扩张延长症(vertebrobasilar dolichoectasia, VBD)，是一种颅内血管变异性疾病，发病机制尚未完全明确，可能与遗传或先天性因素有关。其异常的血管会导致多种临床疾病，包括脑卒中、脑积水、颅神经受压等。VBD所致的颅神经受压综合征的发病率逐年提高，随着医学影像学及血流动力学的发展，更多的无创检查及更清晰的图像为临床及相关研究提供了更好的条件，加之其本身可能导致的脑卒中等疾病，严重威胁患者的生命健康。因此，就椎–基底动脉(vertebrobasilar artery, VBA)迂曲延长综合征引起的相应症状及其存在的风险，从流行病学、临床症状及血管内治疗进展等方面研究进展作一综述。
Abstract: Vertebrobasilar dolichoectasia (VBD) is a clinically rare intracranial posterior circulatory vascular variant disorder whose pathogenesis is not fully understood and may be related to genetic or con-genital factors. Its abnormal blood vessels can lead to a variety of clinical diseases, including stroke, hydrocephalus, cranial nerve compression, etc. With the development of medical imaging and he-modynamics, more non-invasive examinations and clearer images are provided conditions for clin-ical and related research, due to stroke and other diseases that may lead by themselves, seriously threatening patients’ life and health. Therefore, the corresponding symptoms and risks caused by vertebrobasilar artery (VBA) dolichoectasia syndrome are reviewed from the aspects of epidemiol-ogy, clinical manifestations and treatment.
文章引用：董俊君, 郑勇. 椎–基底动脉扩张延长症的血管内诊治研究进展[J]. 临床医学进展, 2023, 13(10): 16662-16669. https://doi.org/10.12677/ACM.2023.13102332

参考文献

[1] Flemming, K.D., Wiebers, D.O., Brown, R.D., Link, M.J., Huston, J., McClelland, R.L. and Christianson, T.J. (2005) The Natural History of Radiographically Defined Vertebrobasilar Nonsaccular Intracranial Aneurysms. Cerebrovascular Diseases, 20, 270-279. [Google Scholar] [CrossRef] [PubMed]
[2] Passero, S.G. and Rossi, S. (2008) Natural History of Vertebrobasilar Dolichoectasia. Neurology, 70, 66-72 [Google Scholar] [CrossRef] [PubMed]
[3] Gutierrez, J., Sultan, S., Bagci, A., et al. (2013) Circle of Willis Configuration as a Determinant of Intracranial Dolichoectasia. Cerebrovascular Diseases, 36, 446-453. [Google Scholar] [CrossRef] [PubMed]
[4] Samim, M., Goldstein, A., Schindler, J., et al. (2016) Multimodality Im-aging of Vertebrobasilar Dolichoectasia: Clinical Presentations and Imaging Spectrum. Radio Graphics, 36, 1129-1146. [Google Scholar] [CrossRef] [PubMed]
[5] Lou, M. and Caplan, L.R. (2010) Vertebrobasilar Dilatative Arteriopa-thy (Dolichoectasia). Annals of the New York Academy of Sciences, 1184, 121-133. [Google Scholar] [CrossRef] [PubMed]
[6] Wolters, F.J., Rinkel, G.J. and Vergouwen, M.D. (2013) Clinical Course and Treatment of Vertebrobasilar Dolichoectasia: A Systematic Review of the Literature. Neurological Research, 2, 131-137. [Google Scholar] [CrossRef] 
[7] Schievink, W.I., Torres, V.E., Wiebers, D.O., et al. (1997) Intracranial Arterial Dolichoectasia in Autosomal Dominant Polycystic Kidney Disease. Journal of the American Society of Nephrology, 8, 1298-1303. [Google Scholar] [CrossRef] 
[8] Toyoshima, Y., Emura, I., Umeda, Y., et al. (2012) Vertebral Basilar System Dolichoectasia with Marked Infiltration of IgG4-Containing Plasma Cells: A Manifestation of IgG4-Related Disease? Neuropathology, 32, 100-104. [Google Scholar] [CrossRef] [PubMed]
[9] Smoker, W.B., Corbell, J.J., Gentry, L.R., et al. (1986) High-Resolution Computed Tomography of the Basilar Artery: Vertebrobasilar Dolichoectasia: Clinical-Pathologic Cor-relation and Review. American Journal of Neuroradiology, 7, 61-72.
[10] Ubogu, E.E. and Zaidat, O.O. (2004) Verte-brobasilar Dolichoectasia Diagnosed by Magnetic Resonance Angiography and Risk of Stroke and Death: A Cohort Study. Journal of Neurology, Neurosurgery, and Psychiatry, 75, 22-26.
[11] Kumral, E., Kisabay, A., Atac, C., et al. (2005) The Mechanism of Ischemic Stroke in Patients with Dolichoectatic Basilar Artery. European Journal of Neurolo-gy, 12, 437-444. [Google Scholar] [CrossRef] [PubMed]
[12] Titlic, M., Tonkic, A., Jukic, I., Kolic, K. and Dolic, K. (2008) Clinical Manifestations of Vertebrobasilar Dolichoectasia. Bratislavske Lekarske Listy, 109, 528-530.
[13] 汤亚男, 朱英标, 卢丽萍, 等. 椎基底动脉延长扩张症165例临床特征分析[J]. 中风与神经疾病杂志, 2013, 30(1): 41-44.
[14] Del Brutto, V.J., Gutierrez, J., Goryawala, M.Z., Sacco, R.L., Rundek, T. and Romano, J.G. (2021) Prevalence and Clinical Correlates of Intracranial Dolichoectasia in Individuals with Ischemic Stroke. Stroke, 52, 2311-2318. [Google Scholar] [CrossRef] 
[15] Conradie, J.M. and Bonnet, E.G. (2021) Dolichoectasia and Its Diagnostic Criteria: A Case Report and Literature Review. Cureus, 13, e12516. [Google Scholar] [CrossRef] [PubMed]
[16] Takeuchi, S., Takasato, Y., Masaoka, H., Hayakawa, T., Otani, N., Yoshino, Y., Yatsushige, H. and Sugawara, T. (2009) Dolichoectasia Involving the Vertebrobasilar and Carotid Artery Systems. Journal of Clinical Neuroscience, 16, 1344-1346. [Google Scholar] [CrossRef] [PubMed]
[17] 张丽, 万慧, 韩国哲, 等. 缺血性卒中患者椎基底动脉扩张延长症的临床和影像学特征: 回顾性病例系列研究[J]. 国际脑血管病杂志, 2012(20): 672-677.
[18] Pico, F., Labreuche, J., Gourfinkel-An, I., et a1. (2006) Basilar Artery Diam-eter and 5-Year Mortality in Patients with Stroke. Stroke, 37, 2342-2347. [Google Scholar] [CrossRef] 
[19] 马允利, 孔莹, 徐雪, 等. 椎-基底动脉扩张延长症患者发生后循环梗死的相关因素分析[J]. 神经损伤与功能重建, 2020, 15(3): 170-172.
[20] Cao, S., Zhai, M., He, J., Cui, P., Ge, T., Wang, J., Xu, W., Wang, R. and Xia, M. (2023) Prevalence and Associated Factors of Basilar Artery Dolichosis in Patients with Acute Cerebral Infarction. Frontiers in Medicine, 10, Article ID: 832878. [Google Scholar] [CrossRef] [PubMed]
[21] Cao, S., Zhai, M., He, J., Wang, J., Ge, T., Wu, Q., Ni, X., Cui, P., Xu, W. and Xia, M. (2023) Basilar Artery Curvature Increases the Risk of Posterior Circulation Infarction Occurrence in Patients without Vertebrobasilar Stenosis. Neurological Sciences, 44, 1273-1280. [Google Scholar] [CrossRef] [PubMed]
[22] Yuan, Y., Xu, K., Luo, Q. and Yu, J. (2014) Research Progress on Verbebrobasilar Dolichoectasia. International Journal of Medical Sciences, 11, 1039-1048 [Google Scholar] [CrossRef] [PubMed]
[23] Wang, Y., Cheng, W. and Lian, Y. (2019) Vertebrobasilar Dolichoectasia and Basilar Artery Dissection Presenting with Trigeminal Neuralgia: A Case Report. Frontiers in Neurology, 10, Article 491. [Google Scholar] [CrossRef] [PubMed]
[24] Kumar, K., Das, K.K., Singh, S., et al. (2019) Vascular Offenders in Trigeminal Neuralgia: A Unified Classification and Assessment of the Outcome of Microvascular Decompression. World Neurosurgery, 127, e366-e375. [Google Scholar] [CrossRef] [PubMed]
[25] Kim, K.J., Kim, J.M., Yun, J.B., et al. (2016) The Association between Vertebrobasilar Dolichoectasia and Hemifacial Spasm. Parkinsonism & Related Disorders, 32, 54-59. [Google Scholar] [CrossRef] [PubMed]
[26] Zaidi, H.A., Awad, A., Chowdhry, S.A., et al. (2015) Mi-crovascular Decompression for Hemifacial Spasm Secondary to Vertebrobasilar Dolichoectasia: Surgical Strategies, Technical Nuances and Clinical Outcomes. Journal of Clinical Neuroscience, 22, 62-68. [Google Scholar] [CrossRef] [PubMed]
[27] Gilbow, R.C., Ruhl, D.S. and Hashisaki, G.T. (2018) Unilateral Sensorineural Hearing Loss Associated with Vertebrobasilar Dolichoectasia. Otology & Neurotology, 39, e56-e57. [Google Scholar] [CrossRef] 
[28] Mortzos, P., Sørensen, T.L., Bialasiewicz, A.A., et al. (2013) Visual Loss, Homonymous Hemianopia, and Unilateral Optic Neuropathy as the Presenting Symptoms of Verte-brobasilar Dolichoectasia. Case Reports in Ophthalmological Medicine, 2013, Article ID: 562393. [Google Scholar] [CrossRef] [PubMed]
[29] Tuzcu, E.A., Bayarogullari, H., Coskun, M., Yilmaz, C., Ilhan, N., Dag-lioglu, M.C. and Aras, M. (2013) Bilateral Abducens Paralysis Secondary to Compression of Abducens Nerve Roots by Vertebrobasilar Dolichoectasia. Neuro-Ophthalmology, 37, 254-256. [Google Scholar] [CrossRef] [PubMed]
[30] Karasudani, K., Ito, Y., Muroi, A., Sato, M., Marushima, A., Hayakawa, M., Matsumaru, Y. and Ishikawa, E. (2022) Endoscopic Third Ventriculostomy for Noncommunicating Hy-drocephalus by Vertebrobasilar Dolichoectasia: A Case Report. Surgical Neurology International, 13, Article 166. [Google Scholar] [CrossRef] 
[31] Passero, S.G., Calchetti, B. and Bartalini, S. (2005) Intracranial Bleeding in Patiants with Vertebrobasilar Dolichoectasia. Stroke, 36, 1421-1425. [Google Scholar] [CrossRef] 
[32] Bin-Alamer, O., Qedair, J., Palmisciano, P., Mallela, A.N., Nayar, G.M., Lu, V.M., Labib, M.A., Lang, M.J., Gross, B.A., Langer, D.J., Couldwell, W.T., Friedlander, R.M. and Abou-Al-Shaar, H. (2023) Dolichoectatic Vertebrobasilar Aneurysms: A Systematic Review and Meta-Analysis of Management Strategies and Outcomes. Neurosurgical Focus, 54, E9. [Google Scholar] [CrossRef] 
[33] Pumar, J.M., Garcia-Dorrego, R., Nieto, A., et al. (2010) Vas-cular Reconstruction of a Fusiform Basilar Aneurysm with the Silk Embolization System. Journal of NeuroInterventional Surgery, 2, 242-244. [Google Scholar] [CrossRef] [PubMed]
[34] Fiorella, D., Kelly, M.E., Albuquerque, F.C., et al. (2009) Cura-tivereconstruction of a Giant Midbasilar Trunk Aneurysm with the Pipeline Embolization Device. Neurosurgery, 64, 212-217. [Google Scholar] [CrossRef] 
[35] Siddiqui, A.H., Abla, A.A., Kan, P., et al. (2012) Panacea or Problem: Flow Diverters in the Treatment of Symptomatic Large or Giant Fusiform Vertebrobasilar Aneu-rysms. Journal of Neurosurgery, 116, 1258-1266. [Google Scholar] [CrossRef] 
[36] van Oel, L.I., van Rooij, W.J., Sluzewski, M., et al. (2013) Re-constructive Endovascular Treatment of Fusiform and Dissecting Basilar Trunk Aneurysms with Flow Diverters, Stents, and Coils. American Journal of Neuroradiology, 34, 589-595. [Google Scholar] [CrossRef] 
[37] Wu, X., Xu, Y., Hong, B., et al. (2013) Endovascular Reconstruction for Treatment of Vertebrobasilar Dolichoectasia: Long-Term Outcomes. American Journal of Neuroradiology, 34, 583-588. [Google Scholar] [CrossRef] 
[38] Chen, Z., Yang, Y., Miao, H., et al. (2013) Endovascular Treatment for Large and Giant Fusiform Aneurysms of the Vertebrobasilar Arteries. Clinical Imaging, 37, 227-231. [Google Scholar] [CrossRef] [PubMed]
[39] 何旭英, 段传志, 张剑波, 等. 支架置入治疗椎-基底动脉延长扩张症安全性和有效性的初步观察[J]. 中国脑血管病杂志, 2018, 15(9): 483-488.
[40] Ji, Z., Yang, W., Ma, Y., Bian, L., Li, G., Fu, Y., Piao, Y. and Zhang, H. (2023) Case Report: Late In-Stent Thrombosis in a Patient with Ver-tebrobasilar Dolichoectasia after Stent-Assisted Coil Embolization Due to the Discontinuation of Antiplatelet Therapy. Frontiers in Neurology, 14, Article ID: 1129816. [Google Scholar] [CrossRef] [PubMed]

为你推荐