转氨酶明显升高的病因及诊治

Etiology and Diagnosis and Treatment of Markedly Elevated Transaminases

摘要: 肝功能检查已经是各个医院常规的血液生化检查，其中天冬氨酸氨基转移酶(AST)、丙氨酸氨基转移酶(ALT)水平异常通常提示有肝细胞的损伤，需要进一步检查明确病因，其病因对死亡率有显著影响，氨基转移酶水平明显升高是临床工作中常见的问题，明确氨基转移酶重度升高的病因是临床工作中的一大难题，我们主要概述了可能导致氨基转移酶重度升高的各种病因及诊治。

Abstract: Liver function tests have been routine blood biochemical tests in various hospitals, in which ab-normal levels of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) are usually indicative of hepatocellular damage and require further investigation to clarify the etiology of the disease, which can have a significant impact on mortality, and a markedly elevated level of ami-notransferase is a common problem in the clinical workup. Defining the etiology of severely elevat-ed aminotransferases is a major challenge in the clinical workup, and we focus on outlining the var-ious etiological factors that may lead to severe elevation of aminotransferases and the diagnosis and management of the disease.