质谱技术在头颈癌分子标志物探究中的应用
Application of Mass Spectrometry Technology in Exploring Molecular Markers of Head and Neck Cancer
DOI: 10.12677/ACM.2023.13112402, PDF,   
作者: 孙宏洋：内蒙古医科大学第一临床医学院，内蒙古 呼和浩特
关键词: 质谱技术；头颈癌；分子标志物；Mass Spectrometry； Head and Neck Cancer； Molecular Markers
摘要: 头颈癌(HNC)是世界上第六大常见癌症，包括发生在几个部位的肿瘤(口腔和鼻腔、鼻窦、唾液腺、咽和喉)。但疗效和预后不能令人满意。早诊断、早治疗是提高生存率、改善患者生活质量、降低病死率的关键。质谱技术的飞速发展为疾病的诊断提供了新方法，该技术被广泛应用于头颈癌分子标志物的探究中。主要介绍质谱技术在头颈癌患者的各种类型标本(如血液、唾液、尿液)中探究标志物的进展，对质谱技术在头颈癌诊断，治疗，预后等方面的应用进行综述。
Abstract: Head and neck carcinoma (HNC) is the sixth most common cancer in the world and includes tu-mours that occur in several sites (oral and nasal cavities, sinuses, salivary glands, pharynx and lar-ynx). However, the outcome and prognosis are unsatisfactory. Early diagnosis and treatment are key to increasing survival rates, improving patients’ quality of life and reducing mortality rates. The rapid development of mass spectrometry has provided new methods for the diagnosis of the disease, and the technique is widely used in the exploration of molecular markers for head and neck cancer. This article introduces the progress of mass spectrometry in the detection of markers in various types of specimens (blood, saliva, urine) from head and neck cancer patients, and provides a review of the application of mass spectrometry in the diagnosis, treatment and prognosis of head and neck cancer.
文章引用：孙宏洋. 质谱技术在头颈癌分子标志物探究中的应用[J]. 临床医学进展, 2023, 13(11): 17139-17145. https://doi.org/10.12677/ACM.2023.13112402

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