基于CRISPR/Cas系统的即时诊断研究进展
Progress in Point-of-Care Diagnosis Based on CRISPR/Cas System
DOI: 10.12677/JSTA.2023.116056, PDF,    科研立项经费支持
作者: 杨赛男, 戴 斌, 李 平, 刘 宾, 王诗琪, 何昱嫦, 吕 圆*:湖南环境生物职业技术学院,湖南 衡阳
关键词: CRISPR/Cas分子诊断现场检测 CRISPR/Cas Molecular Diagnostic Point of Care
摘要: 面对突发公共卫生事件,快速、准确和便携的现场检测至关重要。基于CRISPR/Cas技术的分子诊断是目前现场检测主要方法,可以与多种信号传感方法相结合,集成到智能设备中,开发多个检测新平台。本文介绍基于CRISPR/Cas系统的传感器发展和现场应用,对CRISPR和现场检测的发展前景进行总结和展望。
Abstract: Fast, accurate and portable onsite testing is critical in the face of public health emergencies. Molecular diagnosis based on CRISPR/Cas technology is currently the main method of detection, which can be combined with a variety of signal sensing methods, integrated into smart devices, and develop multiple new detection platforms. This paper introduces the sensor development and field application based on CRISPR/Cas system, and summarizes and prospects the development prospect of CRISPR and field detection.
文章引用:杨赛男, 戴斌, 李平, 刘宾, 王诗琪, 何昱嫦, 吕圆. 基于CRISPR/Cas系统的即时诊断研究进展[J]. 传感器技术与应用, 2023, 11(6): 493-504. https://doi.org/10.12677/JSTA.2023.116056

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