非手术肺癌患者肺康复疗效的Meta分析
Meta Analysis of the Effect of Lung Rehabilitation on Non-Operation Lung Cancer Patients
DOI: 10.12677/ACM.2023.13112447, PDF,   
作者: 魏 娜, 孙艳丽：西安市中心医院呼吸与危重症医学科，陕西 西安 2延安大学医学院，陕西 延安；杨 莉*, 李建英, 范亚莉：西安市中心医院呼吸与危重症医学科，陕西 西安；张巧玲：西安市中心医院护理部，陕西 西安
关键词: 肺癌；非手术；放化疗；肺康复；Meta分析；Lung Cancer； Non-Operation； Radiochemotherapy； Lung Rehabilitation； Meta Analysis
摘要: 目的：系统评价肺康复对非手术肺癌患者的运动能力、肺功能、负性情绪及生活质量的影响。方法：通过检索PubMed、EMbase、Web of Science、中国期刊全文数据库(CNKI)、维普数据库(VIP)、万方数据知识服务平台(Wan Fang Data) 6个数据库中肺康复治疗非手术肺癌患者临床试验研究的相关文献，检索日期为建库至2023年6月30日。使用RevMan5.4软件进行结果分析。结果：共纳入文献7篇，病人546例，Meta分析结果显示：进行肺康复干预后患者6MWD明显提高(MD = 22.96)；肺功能指标：一秒用力呼气量(MD = 0.21)、用力肺活量(MD = 0.29)、最大通气量(MD = 12.14)明显改善；生活质量(SF-36)得到提高。结论：肺康复训练对非手术肺癌患者来说，可以提高运动能力和肺功能水平，改善其生活质量。
Abstract: Objective: To systematically evaluate the impact of lung rehabilitation on motor ability, lung func-tion, negative emotions, and quality of life in non-operation lung cancer patients. Methods: The rel-evant articles of clinical trial research on lung rehabilitation for non-operation lung cancer patients in PubMed, EMbase, Web of Science, CNKI, VIP and Wan Fang Data databases were retrieved from June 30, 2023. Using RevMan5.4 software for analysis. Result: A total of 7 articles were included, with 546 patients. Meta analysis showed that after lung rehabilitation intervention, the 6MWD of patients significantly increased (MD = 22.96); Pulmonary function indicators: forced expiratory volume per second (MD = 0.21), forced vital capacity (MD = 0.29), and maximum ventilation volume (MD = 12.14) were significantly improved; The quality of life (SF-36) has been improved. Conclusion: Lung rehabilitation training can improve exercise ability and lung function levels, and improve the quality of life for non-operation lung cancer patients.
文章引用：魏娜, 孙艳丽, 杨莉, 张巧玲, 李建英, 范亚莉. 非手术肺癌患者肺康复疗效的Meta分析[J]. 临床医学进展, 2023, 13(11): 17465-17472. https://doi.org/10.12677/ACM.2023.13112447

参考文献

[1] American Cancer Society (2022) Key Statistics for Lung Cancer.
https://www.cancer.org/cancer/lung-cancer/about/key-statistics.html
[2] 国家卫生健康委办公厅. 原发性肺癌诊疗指南(2022年版) [J]. 协和医学杂志, 2022, 13(4): 549-570.
[3] Bruni, A., Scotti, V., Borghetti, P., Vagge, S., Cozzi, S., D’Angelo, E., Giaj Levra, N., Fozza, A., Taraborrelli, M., Piperno, G., Vanoni, V., Sepulcri, M., Trovò, M., Nardone, V., Lattanzi, E., Bou Selman, S., Bertolini, F., Franceschini, D., Agustoni, F., Jereczek-Fossa, B.A., Magrini, S.M., Livi, L., Lohr, F. and Filippi, A.R. (2021) Corrigendum: A Real-World, Multicenter, Observational Retrospective Study of Durvalumab after Concomitant or Sequential Chemoradiation for Unresectable Stage III Non-Small Cell Lung Cancer. Frontiers in Oncology, 11, Article 802949. [Google Scholar] [CrossRef] [PubMed]
[4] Saito, H., Hatakeyama, K., Konno, H., et al. (2017) Impact of Pul-monary Rehabilitation on Postoperative Complications in Patients with Lung Cancer and Chronic Obstructive Pulmonary Disease. Thoracic Cancer, 8, 451-460. [Google Scholar] [CrossRef] [PubMed]
[5] Spruit, M.A., Singh, S.J., Garvey, C., et al. (2013) An Official American Thoracic Society/European Respiratory Society Statement: Key Concepts and Advances in Pulmonary Rehabil-itation. American Journal of Respiratory and Critical Care Medicine, 188, e13-e64.
[6] 邵楚楚, 王婉莹, 任胜祥. CSCO非小细胞肺癌诊疗指南(2021版)解读[J]. 同济大学学报(医学版), 2022, 43(1): 1-9.
[7] Millan, J., Pintó, X., Brea, A., Blasco, M., Hernández-Mijares, A., Ascaso, J., Diaz, A., Mantilla, T. and Pedro-Botet, J. (2018) Fibrates in the Secondary Prevention of Cardiovascular Disease (Infarction and Stroke). Results of a Systematic Review and Me-ta-Analysis of the Cochrane Collaboration. Clínica e Investigación en Arteriosclerosis (English Edition), 30, 30-35. [Google Scholar] [CrossRef] 
[8] Borghetti, P., Branz, J., Volpi, G., Pancera, S., Buraschi, R., Bianchi, L.N.C., Bonù, M.L., Greco, D., Facheris, G., Tomasi, C., Pini, L., Bezzi, M., Grisanti, S., Gallazzi, M.S., Bor-ghesi, A., di Monale e Bastia, M.B. and ASST Spedali Civili of Brescia Lung Unit (2022) Home-Based Pulmonary Re-habilitation in Patients Undergoing (Chemo) Radiation Therapy for Unresectable Lung Cancer: A Prospective Explorative Study. La Radiologia Medica, 127, 1322-1332. [Google Scholar] [CrossRef] [PubMed]
[9] 刘娜, 陈彦瑾, 张体新, 等. 肺康复对老年非手术肺癌患者抑郁及生活质量的影响[J]. 老年医学与保健, 2020, 26(5): 808-811, 819.
[10] 赵莉莎, 申旭. 肺康复训练在肺癌患者预后中的作用[J]. 中国康复, 2020, 35(2): 104-107.
[11] 朱烨, 徐敏. 肺康复运动训练对非手术肺癌患者呼吸运动功能、中长期生活质量、生存状况及并发症的影响分析[J]. 实用心脑肺血管病杂志, 2021, 29(S2): 67-69.
[12] 马静, 马胜利, 王进菊. 肺康复运动训练对非手术老年非小细胞肺癌患者预后的影响[J]. 癌症进展, 2020, 18(6): 631-634.
[13] 葛飞. 探讨肺康复对老年非手术肺癌患者抑郁及生活质量的影响[J]. 临床医药文献电子杂志, 2020, 7(A1): 38, 40.
[14] 王丹, 李瑾, 张明, 等. 运动训练对晚期肺癌放疗患者心肺运动功能及生存质量影响的临床研究[J]. 中国康复医学杂志, 2022, 37(4): 501-509.
[15] Lehto, R.H. (2016) Symptom Burden in Lung Cancer: Management Updates. Lung Cancer Management, 5, 61-78. [Google Scholar] [CrossRef] [PubMed]
[16] Sung, H., Ferlay, J., Siegel, R.L., Laversanne, M., Soerjomataram, I., Jemal, A. and Bray, F. (2021) Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA: A Cancer Journal for Clinicians, 71, 209-249. [Google Scholar] [CrossRef] [PubMed]
[17] Schmitz, K.H., Courneya, K.S., Matthews, C., Demark-Wahnefried, W., Galvão, D.A., Pinto, B.M., Irwin, M.L., Wolin, K.Y., Segal, R.J., Lucia, A., Schneider, C.M., von Gruenigen, V.E., Schwartz, A.L. and American College of Sports Medicine (2010) American College of Sports Medicine Roundtable on Exercise Guidelines for Cancer Survivors. Medicine & Science in Sports & Exercise, 42, 1409-1426. [Google Scholar] [CrossRef] 
[18] Cavalheri, V., Burtin, C., Formico, V.R., et al. (2019) Exer-cise Training Undertaken by People within 12 Months of Lung Resection for Non-Small Cell Lung Cancer. Cochrane Database of Systematic Reviews, 6, CD009955. [Google Scholar] [CrossRef] 
[19] 魏志杰, 张靖华, 孟利芳. 呼吸道管理及呼吸训练对肺癌术后患者肺功能指标、排痰效果、肺部感染及康复情况的影响[J]. 癌症进展, 2021, 19(13): 1386-1389, 1402.
[20] 韩允, 项洁, 刘雯, 等. 围手术期肺康复对肺癌术后患者不良情绪的影响[J]. 中国康复, 2021, 36(9): 528-531.
[21] Gregory, J., Dyer, M., Hoyle, C., Mann, H. and Hatswell, A.J. (2020) The Validation of Published Utili-ty Mapping Algorithms: An Example of EORTC QLQ-C30 and EQ-5D in Non-Small Cell Lung Cancer. Health Eco-nomics Review, 10, Article No. 10. [Google Scholar] [CrossRef] [PubMed]

为你推荐