青年脑卒中风险预测因素相关研究
Research on Predictive Factors of Stroke Risk in Young People
DOI: 10.12677/ACM.2023.13112460, PDF,   
作者: 范中沿：承德医学院研究生学院，河北 承德；刘宇鹏*：秦皇岛市第一医院急诊科，河北 秦皇岛
关键词: 脑卒中；青年；危险因素；Stroke； Youth； Risk Factors
摘要: 随着时代发展，青年脑卒中的发病率逐年增加，其复发风险，预后情况，身体残疾等对家庭生活造成较大影响。本综述收集关于青年脑卒中风险因素的相关研究成果。分析发现：各种因素在青年脑卒中的发生发展过程中均起到重要作用，可能参与到细胞的损伤、炎症反应、血液凝固、血栓形成等。
Abstract: With the development of the times, the incidence rate of stroke in young people has increased year by year, and its recurrence risk, prognosis, physical disability, etc. have a greater impact on family life. This review collects relevant research findings on risk factors for stroke in young people. Out-comes: Various factors play an important role in the occurrence and development of stroke in young people, which may be involved in cell damage, inflammatory reactions, blood coagulation, throm-bosis, etc.
文章引用：范中沿, 刘宇鹏. 青年脑卒中风险预测因素相关研究[J]. 临床医学进展, 2023, 13(11): 17555-17560. https://doi.org/10.12677/ACM.2023.13112460

参考文献

[1] 贾娇坤, 刘艳芳, 郭加欢, 等. 白细胞计数、中性粒细胞绝对值及相对值与青年卒中患者预后的相关性研究[J]. 中风与神经疾病杂志, 2022, 39(8): 676-680.
[2] 罗文平, 李小玉, 骆嵩, 等. 血清脂蛋白(a)水平与青年缺血性卒中CISS分型及严重程度的关系[J]. 中华全科医学, 2021, 19(7): 1091-1094, 1102.
[3] 张亚玲, 张顺清, 张芯蕾. 脂蛋白相关磷脂酶A2与青年缺血性脑卒中关系的临床研究[J]. 中国实用神经疾病杂志, 2021, 24(6): 505-510.
[4] Zhou, F., Liu, Y., Shi, H., et al. (2018) Relation between Lipoprotein-Associated Phospholipase A2 Mass and Incident Ischemic Stroke Severity. Neurological Sciences, 39, 1591-1596. [Google Scholar] [CrossRef] [PubMed]
[5] Li, X., Xu, L. and Xu, Z. (2021) The Diagnostic and Prognostic Performance of Lp-PLA2 in Acute Ischemic Stroke. Medicina Clínica, 156, 437-443. [Google Scholar] [CrossRef] [PubMed]
[6] Hu, G., Liu, D., Tong, H., et al. (2019) Lipoprotein-Associated Phospholipase A2 Activity and Mass as Independent Risk Factor of Stroke: A Meta-Analysis. BioMed Research Inter-national, 2019, Article ID: 8642784. [Google Scholar] [CrossRef] [PubMed]
[7] 陈哲周, 李美岩. 血清同型半胱氨酸和脂蛋白(a)与中青年缺血性脑卒中患者的相关研究[J]. 中国民康医学, 2016, 28(18): 11-13. [Google Scholar] [CrossRef] 
[8] 黄振华, 张叶文, 黄惠琴, 等. 同型半胱氨酸与中青年缺血性脑卒中的关系[J]. 深圳中西医结合杂志, 2021, 31(4): 17-19. [Google Scholar] [CrossRef] 
[9] 刘娟, 郑小军, 李会仓, 等. 同型半胱氨酸与青年脑梗死的关系研究[J]. 中国实用神经疾病杂志, 2015(23): 110-111.
[10] 匡俊鑫, 阿力木∙吾甫尔, 韩登峰. 血浆脂蛋白a浓度与新疆地区青年发生急性缺血性脑卒中的关联性研究[J]. 中风与神经疾病杂志, 2021, 38(11): 964-970.
[11] 刘竞丽, 李劲频, 董为伟. 青年缺血性脑卒中与血脂、脂蛋白关系的研究[J]. 广西医科大学学报, 2003, 20(2): 231-232.
[12] 陈宗羡, 田跃雷, 李冬梅. 青年脑卒中患者血清脂蛋白(α)与氧化低密度脂蛋白含量相关性分析[J]. 河北北方学院学报(医学版), 2006, 23(5): 24-25.
[13] 常宇涛. 血清脂蛋白(a)与青年缺血性卒中关系的初步研究[J]. 航空航天医学杂志, 2015, 26(11): 1336-1338.
[14] Bassuk, S.S., Rifai, N. and Ridker, P.M. (2004) High-Sensitivity C-Reactive Protein: Clinical Importance. Current Problems in Cardiology, 29, 439-493. [Google Scholar] [CrossRef] 
[15] Rost, N.S., Wolf, P.A., Kase, C.S., et al. (2001) Plasma Concentration of C-Reactive Protein and Risk of Ischemic Stroke and Transient Ischemic Attack: The Framingham Study. Stroke, 32, 2575-2579. [Google Scholar] [CrossRef] [PubMed]
[16] Di Napoli, M., Papa, F. and Bocola, V. (2001) Prognostic Influence of Increased C-Reactive Protein and Fibrinogen Levels in Ischemic Stroke. Stroke, 32, 133-138. [Google Scholar] [CrossRef] 
[17] Ladenvall, C., Jood, K., Blomstrand, C., et al. (2006) Serum C-Reactive Protein Concentration and Genotype in Relation to Ischemic Stroke Subtype. Stroke, 37, 2018-2023. [Google Scholar] [CrossRef] 
[18] Muir, K.W., Weir, C.J., Alwan, W., et al. (1999) C-Reactive Protein and Outcome after Ischemic Stroke. Stroke, 30, 981-985. [Google Scholar] [CrossRef] 
[19] 贾娇坤, 刘艳芳, 郭加欢, 等. 超敏C反应蛋白和随机血糖与青年卒中患者预后的关系研究[J]. 中国全科医学, 2022, 25(29): 3627-3634.
[20] 周丽坤, 马金珠, 张蕾, 等. 白细胞介素18、热休克蛋白65和和肽素与中青年缺血性脑卒中的相关性研究[J]. 心脑血管病防治, 2021, 21(5): 465-468.
[21] 梁春波, 李江, 黄带发. 老年男性缺血性脑卒中后睡眠障碍相关危险因素分析[J]. 创伤与急危重病医学, 2017, 7(5): 349.
[22] Huang, Y.S., Koo, M., Chen, J.C., et al. (2017) The Association between Tinnitus and the Risk of Ischemic Cerebrovascular Disease in Young and Middleaged Patients: A Secondary Case-Control Analysis of a Nationwide, Population-Based Health Claims Database. PLOS ONE, 12, e0187474. [Google Scholar] [CrossRef] [PubMed]
[23] 王雯, 窦荣花, 黄静, 等. 血尿酸、单核细胞趋化蛋白-1及胱抑素C检测与青年脑卒中患者颅内动脉狭窄的关系研究[J]. 实用医院临床杂志, 2023, 20(1): 23-26.
[24] 汪文兵, 陈后勤, 徐钧, 等. 血清AQP4、GFAP联合检测对急性缺血性脑卒中患者静脉溶栓后出血性转化的预测价值[J]. 临床误诊误治, 2022, 35(5): 102-105.
[25] 张楠, 郦铮铮, 潘思培, 等. 血尿酸、MMP-3水平与银杏达莫注射液治疗大动脉粥样硬化型缺血性脑卒中疗效的相关性[J]. 中国现代医学杂志, 2021, 31(9): 7-12.
[26] 王丽之, 胡灵芝, 吕美艳, 等. 血浆D-二聚体及血小板/淋巴细胞比值对急性缺血性脑卒中青年患者预后的预测作用[J]. 全科医学临床与教育, 2021, 19(1): 11-14.
[27] Yuan, W. and Shi, Z.H. (2014) The Relationship between Plasma D-Dimer Levels and Outcome of Chinese Acute Ischemic Stroke Patients in Different Stroke Subtypes. Journal of Neu-ral Transmission volume, 121, 409-413. [Google Scholar] [CrossRef] [PubMed]
[28] Decker, C.G., Levine, A.J., Maynard, H.D., et al. (2016) Fibro-blast Growth Factor 2 Dimer with Superagonist in Vitro Activity Improves Granulation Tissue Formation during Wound Healing. Biomaterials, 81, 157-168. [Google Scholar] [CrossRef] [PubMed]
[29] Altintas, O., Altintas, M.O., Tasal, A., et al. (2016) The Relationship of Platelet-to-Lymphocyte Ratio with Clinical Outcome and Final Infarct Core in Acute Ischemic Stroke Pa-tients Who Have Undergone Endovascular Therapy. Neurological Research, 38, 759-765. [Google Scholar] [CrossRef] [PubMed]
[30] 贾伟丽, 张玉梅, 贾茜. 开始吸烟年龄与青年卒中的相关性分析[J]. 中风与神经疾病杂志, 2022, 39(6): 489-492.
[31] Bhat, V.M., Cole, J.W., Sorkin, J.D., et al. (2008) Dose-Response Relationship between Cigarette Smoking and Risk of Ischemic Stroke in Young Women. Stroke, 39, 2439-2443. [Google Scholar] [CrossRef] 
[32] Markidan, J., Cole, J.W.,Cronin, C.A., et al. (2018) Smoking and Risk of Ischemic Stroke in Young Men. Stroke, 49, 1276-1278. [Google Scholar] [CrossRef] 
[33] Gan, Y.,Wu, J., Li, L., et al. (2018) Association of Smoking with Risk of Stroke in Middle-Aged and Older Chinese: Evidence from the China National Stroke Prevention Project. Medicine, 97, e13260. [Google Scholar] [CrossRef] 
[34] Larsson, S.C., Burgess, S. and Michaelsson, K. (2019) Smoking and Stroke: A Mendelian Randomization Study. Annals of Neurology, 86, 468-471. [Google Scholar] [CrossRef] [PubMed]

为你推荐