子宫内膜和卵巢原发性双癌与子宫内膜癌卵巢转移的临床特征对比及分析

Comparison and Analysis of the Clinical Fea-tures of SEOC and ECOM

摘要: 子宫内膜和卵巢原发性双癌在临床上较为少见，易被误诊为原发性子宫内膜癌卵巢转移或原发性卵巢癌子宫内膜转移，其鉴别诊断是临床的一大难点，治疗和预后也存在一定的差异。近几年众多研究表明子宫内膜和卵巢原发性双癌实质是一种转移性疾病，更可能是来源于子宫内膜转移至卵巢，但其预后显著好于原发性子宫内膜癌伴卵巢转移。本文旨在对子宫内膜和卵巢原发性双癌与子宫内膜癌伴卵巢转移的临床表现、分子学特征及治疗对比作综述。

Abstract: Synchronous primary endometrial and ovarian cancer is relatively rare in clinic, easily misdiag-nosed as primary endometrial cancer with ovarian metastasis or primary ovarian cancer with en-dometrial metastasis, and its differential diagnosis is a major difficulty in clinic, and its treatment and prognosis also have certain differences. In recent years, many studies have shown that syn-chronous primary endometrial and ovarian cancer is essentially a metastatic disease, which is more likely to originate from the endometrium and metastasize to the ovary, but its prognosis is signifi-cantly better than that of primary endometrial cancer with ovarian metastasis. The purpose of this article is to review the clinical manifestations, molecular features and treatment of synchronous primary endometrial and ovarian cancer compared with primary endometrial cancer with ovarian metastasis.