新生儿血小板输注研究进展
Research Progress in Platelet Transfusion in Neonates
DOI: 10.12677/ACM.2023.13112569, PDF,   
作者: 王 楠：西安医学院研工部，陕西 西安；张 勤：陕西省人民医院新生儿科，陕西 西安
关键词: 新生儿；血小板计数；严重出血风险；血小板输注阈值；Newborn； Platelet Count； Risk of Severe Bleeding； Platelet Infusion Threshold
摘要: 新生儿血小板减少症是新生儿科较常见的可致严重出血风险增加的疾病之一，因其高发病率及与严重出血的相关性，威胁着新生儿的生命安全。输注血小板是升高血小板计数最直接有效的措施，由于成人与新生儿血小板的生理差异，不能简单将成人血小板输注阈值(20 × 109/L)应用于新生儿。目前国际上尚无明确的关于新生儿需要输注血小板的血小板计数的统一指南，于是研究对新生儿进行血小板输注不同阈值对疾病预后及相关并发症的影响，对制定专科指南意义重大。本文主要综述新生儿血小板输注的临床实践及不同血小板输注阈值对疾病的影响，旨在为临床诊疗决策及指南制定提供新的方向。
Abstract: Neonatal thrombocytopenia is one of the most common diseases in neonatology that can increase the risk of severe bleeding. Due to its high incidence and correlation with severe bleeding, it threatens the life safety of neonates. Platelet infusion is the most direct and effective measure to in-crease platelet count. Due to the physiological difference of platelet between adults and neonates, the adult platelet infusion threshold (20 × 109/L) cannot be simply applied to neonates. At present, there is no clear unified guideline for platelet count in neonates that need platelet transfusion in the world. Therefore, the study on the influence of different thresholds of platelet transfusion in neonates on disease prognosis and related complications is of great significance for the formulation of specialized guidelines. This article mainly reviews the clinical practice of platelet transfusion in neonates and the influence of different platelet transfusion thresholds on diseases, in order to pro-vide a new direction for clinical diagnosis and treatment decision-making and guideline formula-tion.
文章引用：王楠, 张勤. 新生儿血小板输注研究进展[J]. 临床医学进展, 2023, 13(11): 18301-18306. https://doi.org/10.12677/ACM.2023.13112569

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