中性粒细胞血小板评分对恶性肿瘤患者预后意义的研究进展
Research Progress on the Prognostic Significance of Neutrophil Platelet Score in Patients with Malignant Tumors
DOI: 10.12677/ACM.2023.13122641, PDF,   
作者: 焦捷睿, 高 颖:青海大学研究生院,青海 西宁;王海久, 王志鑫:青海大学附属医院肝胆外科,青海 西宁
关键词: 恶性肿瘤预后改良的中性粒细胞血小板评分Malignancy Prognosis Improved Neutrophil Platelet Score
摘要: 近年来,越来越多的研究表明中性粒细胞血小板(NPS)评分对癌症患者的预后评估具有重要的临床意义。改良的中性粒细胞血小板评分(mNPS)作为反应机体预后的重要参数,已被报道用于多种类型癌症的预后。本文主要就mNPS对评估癌症患者预后的临床价值做一综述。
Abstract: In recent years, an increasing number of studies have shown that the neutrophil platelet (NPS) score has important clinical significance in evaluating the prognosis of cancer patients. The im-proved neutrophil platelet score (mNPS), as an important parameter reflecting the prognosis of the body, has been reported for the prognosis of various types of cancer. This article mainly reviews the clinical value of mNPS in evaluating the prognosis of cancer patients.
文章引用:焦捷睿, 王海久, 王志鑫, 高颖. 中性粒细胞血小板评分对恶性肿瘤患者预后意义的研究进展[J]. 临床医学进展, 2023, 13(12): 18775-18779. https://doi.org/10.12677/ACM.2023.13122641

参考文献

[1] 陈金东. 中国各类癌症的发病率和死亡率现状及发展趋势[J]. 遵义医学院学报, 2018, 41(6): 653-662.
[2] Okugawa, Y., Toiyama, Y., Yamamoto, A., et al. (2020) Modified Neutrophil-Platelet Score as a Prom-ising Marker for Stratified Surgical and Oncological Outcomes of Patients with Gastric Cancer. Surgery Today, 50, 223-231. [Google Scholar] [CrossRef] [PubMed]
[3] Miao, C., Zhu, S., Pan, H., et al. (2017) Combined Neutro-phil-Platelet Score and Hemoglobin Level Predict Survival in Esophageal Squamous Cell Carcinoma Patients Treated with Chemoradiotherapy. Oncotarget, 8, 87971-87979. [Google Scholar] [CrossRef] [PubMed]
[4] Mantovani, A., Allavena, P., Sica, A., et al. (2008) Cancer-Related Inflammation. Nature, 454, 436-444. [Google Scholar] [CrossRef] [PubMed]
[5] Mohri, Y., Tanaka, K., Toiyama, Y., et al. (2016) Impact of Preoperative Neutrophil to Lymphocyte Ratio and Postoperative Infectious Complications on Survival after Curative Gastrectomy for Gastric Cancer: A Single Institutional Cohort Study. Medicine (Baltimore), 95, e3125. [Google Scholar] [CrossRef
[6] Sreeramkumar, V., Adrover, J.M., Ballesteros, I., et al. (2014) Neutrophils Scan for Activated Platelets to Initiate Inflammation. Science, 346, 1234-1238. [Google Scholar] [CrossRef] [PubMed]
[7] Shaul, M.E. and Fridlender, Z.G. (2019) Tumour-Associated Neu-trophils in Patients with Cancer. Nature Reviews Clinical Oncology, 16, 601-620. [Google Scholar] [CrossRef] [PubMed]
[8] Schmidt, H., Bastholt, L., Geertsen, P., et al. (2005) Elevated Neutrophil and Monocyte Counts in Peripheral Blood Are Associated with Poor Survival in Patients with Metastatic Melanoma: A Prognostic Model. British Journal of Cancer, 93, 273-278. [Google Scholar] [CrossRef] [PubMed]
[9] Lechner, M.G., Liebertz, D.J. and Epstein, A.L. (2010) Characterization of Cytokine-Induced Myeloid-Derived Suppressor Cells from Normal Human Peripheral Blood Mononuclear Cells. The Journal of Immunology, 185, 2273-2284. [Google Scholar] [CrossRef] [PubMed]
[10] Khorana, A.A., Kuderer, N.M., Culakova, E., et al. (2008) Devel-opment and Validation of a Predictive Model for Chemotherapy-Associated Thrombosis. Blood, 111, 4902-4907. [Google Scholar] [CrossRef] [PubMed]
[11] Demers, M. and Wagner, D.D. (2014) NETosis: A New Fac-tor in Tumor Progression and Cancer-Associated Thrombosis. Seminars in Thrombosis and Hemostasis, 40, 277-283. [Google Scholar] [CrossRef] [PubMed]
[12] Demers, M., Krause, D.S., Schatzberg, D., et al. (2012) Cancers Pre-dispose Neutrophils to Release Extracellular DNA Traps That Contribute to Cancer-Associated Thrombosis. Proceedings of the National Academy of Sciences of the United States of America, 109, 13076-13081. [Google Scholar] [CrossRef] [PubMed]
[13] Bystricky, B., Reuben, J.M. and Mego, M. (2017) Circulating Tu-mor Cells and Coagulation-Minireview. Critical Reviews in Oncology/Hematology, 114, 33-42. [Google Scholar] [CrossRef] [PubMed]
[14] Naschitz, J.E., Yeshurun, D., Eldar, S., et al. (1996) Diagno-sis of Cancer-Associated Vascular Disorders. Cancer, 77, 1759-1767. [Google Scholar] [CrossRef
[15] Ishizuka, M., Nagata, H., Takagi, K., et al. (2012) Preoperative Thrombocytosis Is Associated with Survival after Surgery for Colorec-tal Cancer. Journal of Surgical Oncology, 106, 887-891. [Google Scholar] [CrossRef] [PubMed]
[16] Martinod, K. and Wagner, D.D. (2014) Thrombosis: Tangled up in NETs. Blood, 123, 2768-2776. [Google Scholar] [CrossRef] [PubMed]
[17] Watt, D.G., Proctor, M.J., Park, J.H., et al. (2015) The Neu-trophil-Platelet Score (NPS) Predicts Survival in Primary Operable Colorectal Cancer and a Variety of Common Cancers. PLOS ONE, 10, e0142159. [Google Scholar] [CrossRef] [PubMed]
[18] Oliphant, R., Nicholson, G.A., Horgan, P.G., et al. (2013) Con-tribution of Surgical Specialization to Improved Colorectal Cancer Survival. British Journal of Surgery, 100, 1388-1395. [Google Scholar] [CrossRef] [PubMed]
[19] Yamada, S., Gotoh, T., Nakashima, Y., et al. (2001) Distribution of Serum C-Reactive Protein and Its Association with Atherosclerotic Risk Factors in a Japanese Population: Jichi Medical School Cohort Study. American Journal of Epidemiology, 153, 1183-1190. [Google Scholar] [CrossRef] [PubMed]
[20] Lakoski, S.G., Cushman, M., Palmas, W., et al. (2005) The Relation-ship between Blood Pressure and C-Reactive Protein in the Multi-Ethnic Study of Atherosclerosis (MESA). Journal of the American College of Cardiology, 46, 1869-1874. [Google Scholar] [CrossRef] [PubMed]
[21] Mcdade, T.W., Rutherford, J.N., Adair, L., et al. (2009) Population Differences in Associations between C-Reactive Protein Concentration and Adiposity: Comparison of Young Adults in the Philippines and the United States. The American Journal of Clinical Nutrition, 89, 1237-1245. [Google Scholar] [CrossRef] [PubMed]
[22] Dogan, M., Algin, E., Guven, Z.T., et al. (2018) Neutro-phil-Lymphocyte Ratio, Platelet-Lymphocyte Ratio, Neutrophil-Platelet Score and Prognostic Nutritional Index: Do They Have Prognostic Significance in Metastatic Pancreas Cancer? Current Medical Research and Opinion, 34, 857-863. [Google Scholar] [CrossRef] [PubMed]
[23] Moyes, L.H., Leitch, E.F., Mckee, R.F., et al. (2009) Pre-operative Systemic Inflammation Predicts Postoperative Infectious Complications in Patients Undergoing Curative Resec-tion for Colorectal Cancer. British Journal of Cancer, 100, 1236-1239. [Google Scholar] [CrossRef] [PubMed]
[24] Leitch, E.F., Chakrabarti, M., Crozier, J.E., et al. (2007) Comparison of the Prognostic Value of Selected Markers of the Systemic Inflammatory Response in Patients with Colorectal Cancer. British Journal of Cancer, 97, 1266-1270. [Google Scholar] [CrossRef] [PubMed]
[25] Canna, K., Mcardle, P.A., Mcmillan, D.C., et al. (2005) The Relation-ship between Tumour T-Lymphocyte Infiltration, the Systemic Inflammatory Response and Survival in Patients Under-going Curative Resection for Colorectal Cancer. British Journal of Cancer, 92, 651-654. [Google Scholar] [CrossRef] [PubMed]