循环肿瘤细胞检测在临床癌症的应用进展
Advances in Circulating Tumor Cell Assays for Clinical Cancer Applications
DOI: 10.12677/ACM.2023.13122681, PDF,   
作者: 张宁伟, 任 宾*:青海大学附属医院肝胆胰外科,青海 西宁
关键词: 循环肿瘤细胞癌症液体活检肿瘤诊断Circulating Tumor Cells Cancer Liquid Biopsy Tumor Diagnosis
摘要: 随着精准医学的发展,液体活检技术开始在临床上广泛应用。循环肿瘤细胞(CTC)是从原发性肿瘤脱离进入外周血液循环的肿瘤细胞,经过一系列迁移、黏附和聚集后形成新的转移。CTC的检测和分析作为一种新型的无创性诊断工具,可以用于协助临床上肿瘤的诊断和治疗效果监测,并且可以预测肿瘤的复发等。本文就CTC的生物学特性、目前临床常用的检测方法以及在不同实体瘤临床中的应用价值展开综述。
Abstract: With the development of precision medicine, liquid biopsy technology is beginning to be widely used in clinical practice. Circulating tumor cells (CTC) are tumor cells detached from primary tu-mors into the peripheral blood circulation, and form new metastases after a series of migration, adhesion, and aggregation. As a novel noninvasive diagnostic tool, the detection and analysis of CTC can be used to assist in the diagnosis of tumors in the clinic and monitoring of the treatment effect, and it can also predict the recurrence of tumors and so on. In this article, we review the biological characteristics of CTC, the current commonly used clinical detection methods, and the application value in different solid tumors.
文章引用:张宁伟, 任宾. 循环肿瘤细胞检测在临床癌症的应用进展[J]. 临床医学进展, 2023, 13(12): 19062-19071. https://doi.org/10.12677/ACM.2023.13122681

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