对冠状动脉疾病中微循环阻力指数的测定方法的研究进展

Progress in the Study of Methods for the Determination of the Microcirculatory Resistance Index in Coronary Artery Disease

摘要: 心脏供血不足与心绞痛的问题主要源于冠状动脉微血管功能异常。在医学实践里，精准地确定冠状动脉微血管功能状况及其障碍程度并对冠脉微循环功能做出定量分析，这对疾病等级分类和预测结果有着重要的影响。当前，最常用的方法就是利用压力导丝检测微循环阻力指数作为衡量冠状动脉微血管功能障碍的标准，然而这种方式因为额外的时间消耗、费用支出以及注射液的使用等因素而受到限制，无法广泛运用于实际治疗过程中。最近的研究表明，采用冠状动脉造影技术可以有效代替传统的压力导丝法来计算微循环阻力指数。本篇文章将会对此种新技术的理论基础、准确度以及其实际应用效果等方面做全面介绍。

Abstract: The problem of insufficient blood supply to the heart and angina pectoris stems mainly from ab-normal coronary microvascular function. In medical practice, precise determination of the state of coronary microvascular function and its degree of dysfunction and quantitative analysis of coronary microcirculatory function have a significant impact on the classification of disease levels and pre-diction of outcomes. Currently, the most commonly used method to measure coronary microvascu-lar dysfunction is the microcirculatory resistance index using a pressure guidewire; however, this approach is limited by the additional time consumption, cost, and use of injectable fluids and cannot be widely utilized in the actual therapeutic process. Recent studies have shown that coronary angi-ography can be an effective alternative to the traditional pressure guidewire method for calculating the microcirculatory resistance index. The theoretical basis, accuracy, and practical application of this new technique will be presented in this article.