抗β2-糖蛋白1抗体的临床意义
Clinical Significance of Resist β2-Glycoprotein 1 Antibody
DOI: 10.12677/ACM.2023.13122744, PDF,   
作者: 赵雅婷, 帕丽达·阿布利孜:新疆医科大学第一附属医院皮肤科,新疆 乌鲁木齐
关键词: 抗β2-糖蛋白1抗体抗磷脂抗体综述Anti-β2-Glycoprotein 1 Antibody Antiphospholipid Antibody Summary
摘要: 抗β2-糖蛋白1抗体(aβ2-GP1)是以磷脂结合蛋白为靶抗原的抗磷脂抗体。20世纪90年代初,三个研究小组同时发现抗磷脂综合征病人的抗心磷脂抗体识别的是血浆中的β2-糖蛋白1 (β2-GP1),而非心磷脂,由此打开了研究者对β2-GP1的兴趣大门。随着研究进展,目前发现aβ2-GP1在多种疾病的发生发展中起着十分重要的作用。本文将对aβ2-GP1在多种临床疾病中的意义作一综述。
Abstract: Resist β2-Glycoprotein 1 antibody (aβ2-GP1) is an anti phospholipid antibody targeting phospho-lipid binding proteins. In the early 1990s, three research groups simultaneously discovered that the anticardiolipin antibodies in patients with antiphospholipid syndrome recognize the presence of β2-Glycoprotein 1 (β2-GP1), rather than cardiolipin, thus opening up researchers’ understanding of β2-GP1 interest gate. With the progress of research, it has been found that a β2-GP1 plays a cru-cial role in the occurrence and development of various diseases. This article will focus on a β Review the significance of 2-GP1 in various clinical diseases.
文章引用:赵雅婷, 帕丽达·阿布利孜. 抗β2-糖蛋白1抗体的临床意义[J]. 临床医学进展, 2023, 13(12): 19489-19496. https://doi.org/10.12677/ACM.2023.13122744

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