儿童卵巢畸胎瘤临床特征分析

Clinical Characteristics Analysis of Ovarian Teratoma in Children

摘要: 目的：了解儿童卵巢畸胎瘤临床表现、辅助检查、诊断及治疗方式的特点，提高对本病的认识。方法：回顾性分析85例儿童卵巢畸胎瘤患儿的临床诊疗资料分析，归纳总结儿童卵巢畸胎瘤的临床特征。结果：85例卵巢畸胎瘤患儿中，56例(65.88%)以腹痛为就诊原因，腹部包块与查体发现均为9例，以月经不规律、腹胀、排尿困难等就诊11例。部分患儿的甲胎蛋白、CA199、CA125及癌胚抗原均有不同程度升高。CT (86.54%)检出率明显高于超声(68.83%)检查。本组研究65例(76.47%)患儿行腹腔镜手术，其术中出血量、切口长度以及术后住院时间均少于开放手术。随访3例患儿复发，2例为成熟性畸胎瘤，1例2级IV期未成熟畸胎瘤，并伴有胸腔转移。结论：儿童卵巢畸胎瘤的临床表现多样，需要结合相关辅助检查进行综合分析，早期诊断，早期诊断，多可获得较好的预后。腹腔镜手术具有创伤小、恢复快的优势，为临床上首选的治疗方式。

Abstract: Objective: To understand the characteristics of clinical manifestations, auxiliary examination, diag-nosis and treatment of ovarian teratoma in children, and to improve the understanding of this dis-ease. Methods: The clinical diagnosis and treatment data of 85 children with ovarian teratoma were analyzed retrospectively, and the clinical characteristics of children with ovarian teratoma were summarized. Results: Of the 85 children with ovarian teratoma, 56 cases (65.88%) were treated with abdominal pain, 9 cases were found with abdominal mass and only physical examination, and 11 cases were treated with irregular menstruation, abdominal distension, dysuria and so on. The levels of alpha-fetoprotein, CA199, CA125 and carcinoembryonic antigen were increased in some children. The detection rate of CT (86.54%) was significantly higher than that of ultrasound (68.83%). In this study, 65 patients (76.47%) underwent laparoscopic surgery, and the intraopera-tive blood loss, incision length and postoperative hospital stay were less than those of open surgery. Three patients were followed up with recurrent teratoma, 2 with mature teratoma and 1 with im-mature teratoma of grade 2 stage IV, accompanied by thoracic metastasis. Conclusion: The clinical manifestations of ovarian teratoma in children are varied, and it is necessary to give related auxil-iary examination for comprehensive analysis. Early diagnosis and early diagnosis can obtain better prognosis. Laparoscopic surgery has the advantages of less trauma and faster recovery, and is the preferred treatment in clinical practice.