高强度聚焦超声治疗晚期胰腺癌的研究进展
Research Progress of High-Intensity Focused Ultrasound in the Treatment of Advanced Pancreatic Cancer
DOI: 10.12677/ACM.2024.141066, PDF,   
作者: 刘 畅, 陈 庆, 王槐志*：重庆医科大学，重庆；中国科学院重庆绿色智能技术研究院，重庆；中国科学院大学重庆学院，重庆；重庆市人民医院肝胆胰腺外科，重庆
关键词: 高强度聚焦超声；晚期胰腺癌；生存获益；High-Intensity Focused Ultrasound (HIFU)； Advanced Pancreatic Cancer； Survival Benefit
摘要: 高强度聚焦超声(HIFU)在胰腺癌治疗中的应用受到越来越广泛的关注。利用快速升温至破坏肿瘤细胞水平的超声束，HIFU可以选择性地切除目标病变且极小程度地损伤胰腺周围正常组织。大量研究表明了HIFU治疗的安全性、有效性，可以单独使用或结合全身放化疗治疗晚期胰腺癌。它能有效缓解胰腺癌相关腹痛，带来额外的生存获益，且很少有明显的并发症。本文就HIFU技术进行了简要概述，描述了其在晚期胰腺癌治疗中的临床应用，总结了近年来针对HIFU治疗晚期胰腺癌的多项研究，并讨论了HIFU在晚期胰腺癌应用中的未来展望及挑战。
Abstract: The application of high intensity focused ultrasound (HIFU) in the treatment of pancreatic cancer has attracted more and more attention. HIFU can selectively remove the target lesions and mini-mally damage the normal tissues around the pancreas by using the ultrasound beam that rapidly heats up to the level of destroying tumor cells. A large number of studies have shown that HIFU is safe and effective in the treatment of advanced pancreatic cancer. HIFU can be used alone or in combination with systemic radiotherapy and chemotherapy. It can effectively alleviate pancreatic cancer related abdominal pain, bring additional survival benefits, and rarely have obvious compli-cations. This paper gives a brief overview of HIFU, describes its clinical application in the treatment of advanced pancreatic cancer, summarizes a number of studies on HIFU in the treatment of ad-vanced pancreatic cancer in recent years, and discusses the future prospects and challenges of HIFU in the application of advanced pancreatic cancer.
文章引用：刘畅, 陈庆, 王槐志. 高强度聚焦超声治疗晚期胰腺癌的研究进展[J]. 临床医学进展, 2024, 14(1): 456-465. https://doi.org/10.12677/ACM.2024.141066

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