多模态超声模型对子宫内膜癌的研究进展

Research Progress of Multimodal Ultrasound Model on Endometrial Cancer

摘要: 子宫内膜癌(Endometrial cancer, EC)其发病率在全球范围内呈上升趋势，早期诊断EC可以改善患者的长期预后，寻找确切可靠的早期评价指标指导临床EC的治疗显得尤为重要。临床因素、超声特征(二维超声、多普勒超声等)及血清学肿瘤标志物对EC都具有良好的诊断价值，既有采用单一指标，也有多因素联合诊断，多模态超声模型也被证实可有效提高EC的诊断率，但是目前仍没有统一的共识。多模态超声模型在区别宫腔良恶性、预测淋巴结转移、预测子宫肌层浸润深度方面有较好的应用，可优化EC的生存率，在评估预后情况、治疗方案制定上发挥作用。本文对EC的影响因素及多模态超声模型在EC应用中的研究进展等相关问题进行综述。

Abstract: The incidence rate of endometrial cancer (EC) is on the rise worldwide. Early diagnosis of EC can improve the long-term prognosis of patients. It is particularly important to find accurate and relia-ble early evaluation indicators to guide clinical treatment of EC. Clinical treatment, ultrasound fea-tures (such as two-dimensional ultrasound, Doppler ultrasound, etc.), and serological tumor mark-ers all have good diagnostic value for EC. There are both single indicators and multi factor joint di-agnoses, and multimodal ultrasound models have been proven to effectively improve the diagnostic rate of EC. However, there is currently no unified consensus. The multimodal ultrasound model has good applications in distinguishing between benign and malignant uterine cavities, predicting lymph node metastasis, and predicting the depth of uterine myometrial invasion. It can optimize the survival rate of EC and play a role in evaluating prognosis and formulating treatment plans. This article reviews the influencing factors of EC and the research progress of multimodal ultrasound models in the application of EC.