子宫颈高级别鳞状上皮内病变相关问题的进展

Progress of High-Grade Squamous Intraepithelial Lesion of Cervix

摘要: HSIL (子宫颈高级别鳞状上皮内病变)是一种常见的子宫颈病变，其中CIN (子宫颈鳞状上皮内瘤变)分为2级和3级。它的发生与人类感染高危型人乳头瘤病毒(HPV)有关，通过定期筛查，及时发现CIN，并采取有效的治疗措施，可有效降低子宫颈癌的发病率。在HSIL治疗前评估及治疗后随访过程中推荐HPV、TCT联合阴道镜检测目前，子宫颈环形电极切除术是治疗HSIL的首选方法，但术后仍有可能出现病灶残留、复发或恶化的风险，因此，术后应加强监测，并严格执行HSIL的诊断和治疗，以确保子宫颈癌的有效预防。

Abstract: HSIL (high-grade squamous intraepithelial lesion of the cervix) is a common cervical lesion, CIN (cervical squamous intraepithelial neoplasia) was classified into 2 grades and 3 grades. The occur-rence of CIN is related to human infection with high-risk human papillomavirus (HPV). The inci-dence of cervical cancer can be effectively reduced by regular screening, timely detection of CIN and effective treatment measures. HPV, TCT and colposcopy are recommended in the evaluation of HSIL before treatment and follow-up after treatment. At present, cervical circumferential electrode re-section is the first choice for the treatment of HSIL, however, there is still the risk of residual, recur-rence or deterioration after operation. Therefore, it is necessary to strengthen the monitoring and strictly implement the diagnosis and treatment of HSIL to ensure the effective prevention of cervical cancer.