山竹中α-倒捻子素的生物活性研究进展

Research Progress on the Bioactivity of α-Mangostin in Mangosteen

摘要: 山竹(Garcinia mangostana L.)是一种具有营养和药用价值的热带水果，在传统医学中，其果皮常被用于治疗溃疡、炎症、疼痛、腹泻、痢疾和创伤等。山竹广泛的生物活性可能与山竹中的主要活性成分α-倒捻子素有关。α-倒捻子素是山竹果的主要成分，在山竹的多个部位均有分布，包括果壳，果实和树皮等，近年来受到广泛关注。然而，目前还缺乏对α-倒捻子素生物活性的全面总结，这不利于α-倒捻子素的开发。为进一步促进山竹的商业化，本文综述了近年来有关α-倒捻子素生物活性及其分子机制的研究报道，为α-倒捻子素的进一步开发利用提供理论依据。

Abstract: The mangosteen (Garcinia mangostana L.) is a tropical fruit with nutritional and medicinal properties. In traditional medicine, its fruit peel is often used to treat ulcers, inflammation, pain, diarrhea, dysentery and trauma. The wide range of bioactivity of mangosteen may be related to α-mangostin, the main active ingredient in mangosteen. α-Mangostin is the main component of mangosteen, which exists in various parts of mangosteen, including the shell, fruit and bark, etc., and it has received extensive attention in recent years. However, there is a lack of comprehen-sive summary of the ioactivity of α-mangostin, which is not conducive to the development of α-mangostin. In order to further promote the commercialization of mangosteen, the recent reports on the ioactivity and molecular mechanism of α-mangostin were reviewed in this paper, which provided theoretical basis for the further development and utilization of α-mangostin.