溃疡性结肠炎中药灌肠疗法的研究进展

Research Progress on Traditional Chinese Medicine Enema Therapy for Ulcerative Colitis

摘要: 溃疡性结肠炎(Ulcerative Colitis, UC)是一种慢性非特异性炎症性肠病，临床以腹痛、黏液血便、腹泻等为主要症状，发病率逐年升高。西医治疗UC主要有氨基水杨酸、生物制剂、糖皮质激素、免疫抑制剂等方式，但价格昂贵、容易复发且不良反应较大。中药灌肠疗法是一种中医特色治疗方法，具有疗效确切，副作用小、复发率低的优势，但其作用机制仍需进一步研究和探讨，本文对中药灌肠、中药灌肠联合其他中医疗法治疗UC的研究进行概括总结，并对中药灌肠在UC的机制研究进行综述，为进一步研究提供参考。

Abstract: Ulcerative colitis (UC) is a chronic nonspecific inflammatory bowel disease. Its main clinical symp-toms are abdominal pain, mucous bloody stool, diarrhea, etc. The incidence rate is increasing year by year. Western medicine mainly treats UC through methods such as aminosalicylic acid, biological agents, glucocorticoids, immunosuppressants, etc., but they are expensive, prone to recurrence, and have significant adverse reactions. Traditional Chinese medicine enema therapy is a unique treat-ment method of traditional Chinese medicine, which has the advantages of definite therapeutic ef-fect, small side effects, and low recurrence rate. However, its mechanism of action still needs further research and exploration. This article summarizes the research on traditional Chinese medicine enema, traditional Chinese medicine enema combined with other traditional Chinese medicine therapies for treating UC, and summarizes the mechanism of traditional Chinese medicine enema in UC, providing reference for further research.