高血压患者视网膜微循环改变与全身靶器官损害关系的研究进展

Research Progress on the Relationship between the Changes of Retinal Microcirculation and Systemic Target Organ Damage in Patients with Hypertension

摘要: 高血压是一种以体循环动脉压升高为主要临床表现的心血管综合征。急性或慢性的血压升高容易引起心脏、脑、肾脏、眼、外周血管等重要靶器官的结构和功能发生损害。高血压性视网膜病变是眼部最常见的表现，由于视网膜血管与体内其他血管具有相似的胚胎起源，高血压视网膜病变一直被认为是高血压损害其他靶器官的重要标志之一。光学相干断层血管成像(OCTA)是近年来迅速发展并广泛应用于临床的一种非侵入性、高分辨率、可重复的实时光学成像技术，能够无创地对视网膜微循环进行成像并评估眼部微循环状态。相信随着技术的不断进步、数据更精确的分析，OCTA能够为评估全身靶器官损伤提供更多新思路。

Abstract: Hypertension is a cardiovascular syndrome characterized by increased systemic arterial pressure. Acute or chronic increase in blood pressure can easily cause damage to the structure and function of important target organs such as heart, brain, kidney, eye, peripheral blood vessels and so on. Hy-pertensive retinopathy is the most common manifestation of the eye, because the retinal vessels have similar embryonic origin to other blood vessels in the body, hypertensive retinopathy has al-ways been regarded as one of the important signs of hypertensive damage to other target organs. Optical coherence tomography (OCTA) is a non-invasive, high-resolution, repeatable real-time opti-cal imaging technique that has been rapidly developed in recent years and widely used in clinic. It can non-invasively image retinal microcirculation and evaluate the state of ocular microcirculation. It is believed that with the continuous progress of technology and more accurate analysis of the da-ta, OCTA can provide more new ideas for the assessment of systemic target organ damage.