帕金森病与胃饥饿素、瘦素的相关性研究进展
Research Progress of Correlation between Parkinson’s Disease and Ghrelin and Leptin
DOI: 10.12677/ACM.2024.141278, PDF,   
作者: 刘建刚：青海大学研究生院，青海 西宁；朱爱琴*：青海省人民医院老年医学科，青海 西宁
关键词: 帕金森病；胃饥饿素；瘦素；Parkinson’s Disease； Ghrelin； Leptin
摘要: 帕金森病(PD)是一种多见于老年人的神经退行性疾病，以黑质多巴胺能神经元变性、缺失、减少，神经元α-突触核蛋白沉积及路易小体形成为病理特征。胃饥饿素、瘦素具有明确的神经保护作用。本文就PD与胃饥饿素、瘦素的关系进行综述，进一步探讨胃饥饿素、瘦素对PD的影响。
Abstract: Parkinson’s disease (PD) is a neurodegenerative disease that is more common in the elderly. The pathological features of PD are degeneration, loss, and reduction of dopaminergic neurons in the substantia nigra, α-synuclein deposition in neurons, and Lewy body size. Ghrelin and leptin have clear neuroprotective effects. This article reviews the relationship between PD and ghrelin and lep-tin, and further discusses the effects of ghrelin and leptin on PD.
文章引用：刘建刚, 朱爱琴. 帕金森病与胃饥饿素、瘦素的相关性研究进展[J]. 临床医学进展, 2024, 14(1): 1977-1981. https://doi.org/10.12677/ACM.2024.141278

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