卵圆孔未闭与偏头痛的研究进展
Advances on the Relationship between Patent Foramen Ovale and Migraine
DOI: 10.12677/ACM.2024.141298, PDF,   
作者: 陈佳莹, 袁忠明*:重庆医科大学附属第二医院老年医学科,重庆
关键词: 卵圆孔未闭偏头痛超声心动图介入封堵术Patent Foramen Ovale Migraine Echocardiogram Interventional Closure
摘要: 卵圆孔是连接心脏右心房和左心房的正常生理性通道,可引导血流绕过肺循环直接从右心房流向左心房。卵圆孔未闭是卵圆孔闭合失败的结果,是最常见的先天性心脏病,在大约20%至30%的成年人中,卵圆孔仍然是开放的。近年来,大量研究表明偏头痛与卵圆孔未闭存在相关性,但PFO致偏头痛的发病机制至今尚不明确。随着医学技术的发展,PFO可以在临床实践中常规检测诊断。目前经皮卵圆孔封堵术成为治疗卵圆孔未闭合并偏头痛的有效治疗手段。该文围绕PFO的解剖、流行病学、与偏头痛的相关性及其发病机制、诊断、治疗展开综述。
Abstract: The foramen ovale is a normal physiological channel that connects the right atrium and left atrium of the heart, guiding blood flow directly from the right atrium to the left atrium, bypassing the pul-monary circulation. Patent foramen ovale is the result of failure of the foramen ovale to close and is the most common congenital heart disease. In about 20% to 30% of adults, the foramen ovale re-mains open. In recent years, a large number of studies have shown that migraine is related to pa-tent foramen ovale, but the pathogenesis of migraine caused by PFO is still unclear. With the de-velopment of medical technology, PFO can be routinely detected and diagnosed in clinical practice. At present, percutaneous foramen ovale closure has become an effective treatment method for the treatment of unclosed foramen ovale and migraine. This article reviews the anatomy, epidemiology, correlation with migraine, and its pathogenesis, diagnosis, and treatment of PFO.
文章引用:陈佳莹, 袁忠明. 卵圆孔未闭与偏头痛的研究进展[J]. 临床医学进展, 2024, 14(1): 2115-2121. https://doi.org/10.12677/ACM.2024.141298

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