柴胡加龙骨牡蛎汤治疗失眠的研究进展

Research Progress of Bupleurum chinensis and Keel Oyster Soup in Treating Insomnia

摘要: 失眠为一种睡眠障碍表现，通常出现持续性睡眠困难、难以入睡、间歇性醒等。且在睡眠后出现头晕头痛、浑身乏力、情绪低沉、注意力难以集中的情况，对生活质量带来影响。目前临床的主要治疗方式是药物治疗，镇静催眠药的临床疗效显著，但大多数药物具有嗜睡、头昏、乏力等不良反应。传统中药治疗失眠的方法具有独特优势，柴胡加龙骨牡蛎汤作为《伤寒论》中的经典名方，有和解少阳、泄热通腑、镇惊安神的作用，在治疗失眠及其伴随症状等方面临床疗效相对理想，且不良反应低。本研究对失眠常见的发病原因和柴胡加龙骨牡蛎汤的作用机制展开具体分析。

Abstract: Insomnia is a kind of sleep disorder, which usually has persistent sleep difficulty, difficulty falling asleep, intermittent waking and so on. After sleep, dizziness, headache, fatigue, low mood, and dif-ficulty concentrating have an impact on the quality of life. At present, the main clinical treatment is drug therapy, sedative and hypnotic drugs have remarkable clinical efficacy, but most drugs have drowsiness, dizziness, fatigue and other adverse reactions. Traditional Chinese medicine has unique advantages in the treatment of insomnia. As a classic prescription in “On Febrile Diseases”, Bupleu-rum chinensis and Keel Oyster soup has the functions of soothing Shaoyang, dissipating heat and clearing fu-organs, and calming terrors, with relatively ideal clinical efficacy and low adverse reac-tions in the treatment of insomnia and its accompanying symptoms. This study analyzed the com-mon causes of insomnia and the mechanism of action of Bupleurum chinensis and keel oyster soup.