坦度螺酮联合正念认知疗法对焦虑症患者自尊、复原力和应对方式的影响

Effects of Tandospirone Combined with Mindfulness-Based Cognitive Therapy on Self-Esteem, Resilience and Coping Styles in Patients with Anxiety Disorder

摘要: 目的：探讨坦度螺酮联合正念认知疗法对焦虑症患者自尊、复原力和应对方式的影响。方法：将2023年1月~2023年10月在开滦精神卫生中心接受治疗的72例焦虑症患者作为本次研究对象，通过随机数字表法分为研究组和对照组。对照组(n = 36)接受坦度螺酮治疗，研究组(n = 36)在对照组的基础上联合正念认知疗法，两组治疗均持续8周。经过8周治疗后，观察比较两组患者汉密尔顿焦虑量表(HAMA)、自尊量表(SES)、Conner-Davidson量表和应对方式量表(CSQ)评分。结果：1) 与治疗前相比，治疗后患者两组患者HAMA、SES、复原力、CSQ评分明显改善。2) 治疗后，研究组患者HAMA评分低于对照组，SES、复原力评分高于对照组(P < 0.05)；研究组患者应对方式改变显著，解决问题、求助、合理化评分高于对照组，自责、幻想、退避评分低于对照组(P < 0.05)。结论：坦度螺酮联合正念认知疗法能有效提高患者自尊水平和复原力，改变应对方式，从而改善焦虑症状，效果优于单纯药物治疗，值得临床推广。

Abstract: Objective: To investigate the effects of tandospirone combined with mindfulness-based cognitive therapy on self-esteem, resilience and coping style in patients with anxiety disorder. Methods: 72 patients with anxiety disorder who were treated in Kailuan Mental Health Center from January 2023 to October 2023 were divided into study group and control group by random number table method. The control group (n = 36) received tandospirone treatment, and the study group (n = 36) received mindfulness-based cognitive therapy on the basis of the control group. The treatment lasted for 8 weeks in both groups. After 8 weeks of treatment, the scores of Hamilton Anxiety Scale (HAMA), Self-esteem Scale (SES), Conner-Davidson scale and Coping Style Scale (CSQ) were observed and compared between the two groups. Results: 1) Compared with before treatment, HAMA, SES, resilience and CSQ scores of the two groups were significantly improved after treatment. 2) After treatment, HAMA scores in the study group were lower than those in the control group, while SES and resilience scores were higher than those in the control group (P < 0.05); The scores of problem solving, seeking help and rationalization in the study group were higher than those in the control group, and the scores of remorse, fantasy and withdrawal were lower than those in the control group (P < 0.05). Conclusion: Tandospirone combined with mindfulness cognitive therapy can effec-tively improve the self-esteem and resilience of patients, change the coping style, and thus improve the anxiety symptoms. The effect is better than that of drug therapy alone, and it is worthy of clini-cal promotion.