糖皮质激素在不完全性川崎病中的研究进展
Research Progress of Glucocorticoids in Incomplete Kawasaki Disease
DOI: 10.12677/ACM.2024.142337, PDF,   
作者: 张娟娟, 简康欣:西安医学院研工部,陕西 西安;王杰民*:陕西省人民医院儿童病院,陕西 西安
关键词: 不完全川崎病糖皮质激素免疫球蛋白Incomplete Kawasaki Disease Glucocorticoid Immunoglobulin
摘要: 不完全川崎病(IKD)是一种可导致冠状动脉病变(CAL)并发症的系统性血管炎,及时诊断和静脉注射免疫球蛋白(IVIG)是改善预后的关键。糖皮质激素由于它的抗炎性,通常也作为临床治疗的一种方法。
Abstract: Incomplete Kawasaki disease is a systemic vasculitis that can lead to complications of coronary ar-tery disease (CAL), and timely diagnosis and intravenous immunoglobulin (IVIG) are keys to im-proving prognosis. Because of its anti-inflammatory properties, glucocorticoids are also commonly used as a method of clinical treatment.
文章引用:张娟娟, 王杰民, 简康欣. 糖皮质激素在不完全性川崎病中的研究进展[J]. 临床医学进展, 2024, 14(2): 2404-2409. https://doi.org/10.12677/ACM.2024.142337

参考文献

[1] 范雪, 徐明国. 川崎病发病机制及治疗研究进展[J]. 中国实用儿科杂志, 2021, 36(5): 339-344.
[2] 李天颂, 林炎浩, 刁仕明. 儿童不完全川崎病与完全川崎病临床特点对比分析[J]. 基层医学论坛, 2022, 26(8): 148-150.
[3] Chang, L., Yang, H.W., Lin, T/Y and Yang, K.D. (2021) Perspective of Immunopathogenesis and Im-munotherapies for Kawasaki Disease. Frontiers in Pediatrics, 9, Article 697632. [Google Scholar] [CrossRef] [PubMed]
[4] 董彤. 病原体感染与川崎病发病机制关系的研究进展[J]. 国际儿科学杂志, 2020, 47(1): 18-21.
[5] 李瑞燕, 李晓辉, 吴泰相. 川崎病与病原微生物关系的Meta分析[J]. 临床儿科杂志, 2013, 31(1): 69-72.
[6] 董明星, 王喜霞, 焦富勇, 张维华. 川崎病基因多态性的研究进展[J]. 中国当代儿科杂志, 2023, 25(12): 1234- 1238.
[7] 樊志丹, 俞海国, 胡坚, 赖建铭. 中国儿童血管炎诊断与治疗系列专家共识之四——川崎病[J]. 中国实用儿科杂志, 2023(7): 481-488.
[8] Sharma, C., Ganigara, M., Galeotti, C., et al. (2021) Multisystem Inflammatory Syndrome in Children and Kawasaki Disease: A Critical Comparison. Nature Reviews Rheumatology, 17, 731-748. [Google Scholar] [CrossRef] [PubMed]
[9] 焦富勇, 穆志龙, 杜忠东, 杨晓东, 沈捷, 向伟, 王虹. 儿童不完全性川崎病的诊治[J]. 中国当代儿科杂志, 2023, 25(3): 238-243.
[10] Furusho, K., Kamiya, T., Nakano, H, et al. (1984) High-Dose Intravenous Gammaglobulin for Kawasaki Disease. Lancet, 2, 1055-1058. [Google Scholar] [CrossRef
[11] McCrindle, B.W., Rowley, A.H., Newburger, J.W., et al. (2017) Diagnosis, Treatment, and Long-Term Management of Kawasaki Disease: A Scientific Statement for Health Pro-fessionals from the American Heart Association. Circulation, 135, e927-e999. [Google Scholar] [CrossRef
[12] Guiducci, C., Gong, M., Xu, Z., et al. (2010) TLR Recogni-tion of Self Nucleic Acids Hampers Glucocorticoid Activity in Lupus. Nature, 465, 937-941. [Google Scholar] [CrossRef] [PubMed]
[13] Moszyński, K.W. (1970) Sprawie rozpoznawania i leczenia zatoru powietrznego [Diagnosis and Treatment of Air Embolism]. Neurologia i Neurochirurgia Polska, 4, 483-485.
[14] Dominguez, S.R., Birkholz, M., Anderson, M.S., et al. (2019) Diagnostic and Treatment Trends in Chil-dren with Kawasaki Disease in the United States, 2006-2015. The Pediatric Infectious Disease Journal, 38, 1010-1014. [Google Scholar] [CrossRef
[15] Mahieu, P., Bonduelle, Y., Bernard, A., et al. (1984) Acute Diquat Intoxicatio. Interest of Its Repeated Determination in Urine and the Evaluation of Renal Proximal Tubule Integrity. Journal of Toxicology: Clinical Toxicology, 22, 363-369. [Google Scholar] [CrossRef] [PubMed]
[16] Wooditch, A.C. and Aronoff, S.C. (2005) Effect of Initial Cor-ticosteroid Therapy on Coronary Artery Aneurysm Formation in Kawasaki Disease: A Meta-Analysis of 862 Children. Pediatrics, 116, 989-995. [Google Scholar] [CrossRef] [PubMed]
[17] Chen, S., Dong, Y., Kiuchi, M.G., et al. (2016) Coronary Artery Complication in Kawasaki Disease and the Importance of Early Intervention: A Systematic Review and Meta-Analysis. JAMA Pediatrics, 170, 1156-1163. [Google Scholar] [CrossRef] [PubMed]
[18] Green, J., Wardle, A.J. and Tulloh, R.M. (2022) Cortico-steroids for the Treatment of Kawasaki Disease in Children. Cochrane Database of Systematic Reviews, 5, CD011188. [Google Scholar] [CrossRef
[19] Zhao, C.N., Du, Z.D. and Gao, L.L. (2016) Corticosteroid Therapy Might Be Associated with the Development of Coronary Aneurysm in Children with Kawasaki Disease. Chi-nese Medical Journal, 129, 922-928. [Google Scholar] [CrossRef] [PubMed]
[20] Yang, T.J., Lin, M.T., Lu, C.Y., et al. (2018) The Prevention of Coronary Arterial Abnormalities in Kawasaki Disease: A Meta-Analysis of the Corticosteroid Effectiveness. Journal of Microbiology, Immunology and Infection, 51, 321-331. [Google Scholar] [CrossRef] [PubMed]
[21] Franchin, G. and Diamond, B. (2006) Pulse Steroids: How Much Is Enough? Autoimmunity Reviews, 5, 111-113. [Google Scholar] [CrossRef] [PubMed]
[22] Guiducci, C., Gong, M., Xu, Z., et al. (2010) TLR Recognition of Self Nucleic Acids Hampers Glucocorticoid Activity in Lupus. Nature, 465, 937-941. [Google Scholar] [CrossRef] [PubMed]
[23] Newburger, J.W., Sleeper, L.A., McCrindle, B.W., et al. (2007) Ran-domized Trial of Pulsed Corticosteroid Therapy for Primary Treatment of Kawasaki Disease. The New England Journal of Medicine, 356, 663-675. [Google Scholar] [CrossRef
[24] Son, M.B. and Newburger, J.W. (2012) Management of Kawasaki Disease: Corticosteroids Revisited. Lancet, 379, 1571-1572. [Google Scholar] [CrossRef
[25] Singh, S., Sharma, A. and Jiao, F. (2016) Kawasaki Disease: Issues in Diagnosis and Treatment—A Developing Country Perspective. The Indian Journal of Pediatrics, 83, 140-145. [Google Scholar] [CrossRef] [PubMed]
[26] Okubo, Y., Michihata, N., Morisaki, N., et al. (2018) Association between Dose of Glucocorticoids and Coronary Artery Lesions in Kawasaki Disease. Arthritis Care & Research, 70, 1052-1057. [Google Scholar] [CrossRef] [PubMed]
[27] Son, M.B.F., Gauvreau, K., Tremoulet, A.H., et al. (2019) Risk Model Development and Validation for Prediction of Coronary Artery Aneurysms in Kawasaki Disease in a North American Population. Journal of the American Heart Association, 8, e011319. [Google Scholar] [CrossRef
[28] Mitani, M., Ehara, K., Araki, K., Anzo, M. and Bamba, M. (2017) Encephalopathy and Pancreatitis in a 3-Year-Old Girl with Kawasaki Disease. Pediatrics International, 59, 496-498. [Google Scholar] [CrossRef] [PubMed]
[29] Chang, L.S. and Kuo, H.C. (2020) The Role of Corticosteroids in the Treatment of Kawasaki Disease. Expert Review of Anti-Infective Therapy, 18, 155-164. [Google Scholar] [CrossRef] [PubMed]