|
[1]
|
中国医师协会神经内科分会认知障碍专业委员会, 《中国血管性认知障碍诊治指南》编写组. 2019年中国血管性认知障碍诊治指南[J]. 中华医学杂志, 2019, 99(35): 2737-2744.
|
|
[2]
|
陈亦豪, 吴昊, 魏俊吉. 血脑屏障损伤诱发神经病变的评估方法及机制研究进展[J]. 基础医学与临床, 2019, 39(1): 120-124.
|
|
[3]
|
Truettner, J.S., Alonso, O.F. and Dietrich, W.D. (2005) Influence of Therapeutic Hypothermia on Matrix Metalloproteinase Activity after Trau-matic Brain Injury in Rats. Journal of Cerebral Blood Flow & Metabolism, 25, 1505-1516. [Google Scholar] [CrossRef] [PubMed]
|
|
[4]
|
Skillbäck, T., Delsing, L., Synnergren, J., et al. (2017) CSF/Serum Albumin Ratio in Dementias: A Cross-Sectional Study on 1861 Patients. Neurobiology of Aging, 59, 1-9. [Google Scholar] [CrossRef] [PubMed]
|
|
[5]
|
Ueno, M., Chiba, Y., Murakami, R., et al. (2019) Dis-turbance of Intracerebral Fluid Clearance and Blood-Brain Barrier in Vascular Cognitive Impairment. International Jour-nal of Molecular Sciences, 20, Article 2600. [Google Scholar] [CrossRef] [PubMed]
|
|
[6]
|
Tang, H., Gao, Y., Zhang, Q., et al. (2017) Chronic Cerebral Hy-poperfusion Independently Exacerbates Cognitive Impairment within the Pathopoiesis of Parkinson’s Disease via Micro-vascular Pathologys. Behavioural Brain Research, 333, 286-294. [Google Scholar] [CrossRef] [PubMed]
|
|
[7]
|
Himi, N., Takahashi, H., Okabe, N., et al. (2016) Exercise in the Early Stage after Stroke Enhances Hippocampal Brain-Derived Neurotrophic Factor Expression and Memory Function Recovery. Journal of Stroke and Cerebrovascular Diseases, 25, 2987-2994. [Google Scholar] [CrossRef] [PubMed]
|
|
[8]
|
Shu, Y., Zhang, H., Kang, T., et al. (2013) PI3K/Akt Signal Pathway Involved in the Cognitive Impairment Caused by Chronic Cerebral Hypoperfusion in Rats. PLOS ONE, 8, e81901. [Google Scholar] [CrossRef] [PubMed]
|
|
[9]
|
Poh, L., Fann, D.Y., Wong, P., et al. (2021) AIM2 Inflammasome Mediates Hallmark Neuropathological Alterations and Cognitive Impairment in a Mouse Model of Vascular Dementia. Molecular Psychiatry, 26, 4544-4560. [Google Scholar] [CrossRef] [PubMed]
|
|
[10]
|
Bennett, S., Grant, M.M. and Aldred, S. (2009) Oxidative Stress in Vascular Dementia and Alzheimer’s Disease: A Common Pathology. Journal of Alzheimer’s Disease, 17, 245-257. [Google Scholar] [CrossRef]
|
|
[11]
|
Ter Telgte, A., Van Leijsen, E., Wiegertjes, K., et al. (2018) Cerebral Small Vessel Disease: From a Focal to a Global Perspective. Nature Reviews Neurology, 14, 387-398. [Google Scholar] [CrossRef] [PubMed]
|
|
[12]
|
Etherton, M.R., Wu, O. and Rost, N.S. (2016) Recent Advances in Leukoaraiosis: White Matter Structural Integrity and Functional Outcomes after Acute Ischemic Stroke. Current Car-diology Reports, 18, Article No. 123. [Google Scholar] [CrossRef] [PubMed]
|
|
[13]
|
Hu, H.Y., Ou, Y.N., Shen, X.N., et al. (2021) White Matter Hy-perintensities and Risks of Cognitive Impairment and Dementia: A Systematic Review and Meta-Analysis of 36 Prospec-tive Studies. Neuroscience & Biobehavioral Reviews, 120, 16-27. [Google Scholar] [CrossRef] [PubMed]
|
|
[14]
|
Rizvi, B., Narkhede, A., Last, B.S., et al. (2018) The Effect of White Matter Hyperintensities on Cognition Is Mediated by Cortical Atrophy. Neurobiology of Aging, 64, 25-32. [Google Scholar] [CrossRef] [PubMed]
|
|
[15]
|
Bell, R.D., Deane, R., Chow, N., et al. (2009) SRF and Myocardin Regulate LRP-Mediated Amyloid-Beta Clearance in Brain Vascular Cells. Nature Cell Biology, 11, 143-153. [Google Scholar] [CrossRef] [PubMed]
|
|
[16]
|
Akoudad, S., De Groot, M., Koudstaal, P.J., et al. (2013) Cerebral Mi-crobleeds Are Related to Loss of White Matter Structural Integrity. Neurology, 81, 1930-1937. [Google Scholar] [CrossRef] [PubMed]
|
|
[17]
|
Christ, N., Mocke, V. and Fluri, F. (2019) Cerebral Microbleeds Are Associated with Cognitive Decline Early after Ischemic Stroke. Journal of Neurology, 266, 1091-1094. [Google Scholar] [CrossRef] [PubMed]
|
|
[18]
|
Chung, C.P., Chou, K.H., Chen, W.T., et al. (2016) Strictly Lo-bar Cerebral Microbleeds Are Associated with Cognitive Impairment. Stroke, 47, 2497-2502. [Google Scholar] [CrossRef]
|
|
[19]
|
Yakushiji, Y., Noguchi, T., Hara, M., et al. (2012) Dis-tributional Impact of Brain Microbleeds on Global Cognitive Function in Adults without Neurological Disorder. Stroke, 43, 1800-1805. [Google Scholar] [CrossRef]
|
|
[20]
|
Werring, D.J., Frazer, D.W., Coward, L.J., et al. (2004) Cognitive Dysfunction in Patients with Cerebral Microbleeds on T2*-Weighted Gradient-Echo MRI. Brain, 127, 2265-2275. [Google Scholar] [CrossRef] [PubMed]
|
|
[21]
|
Lee, H.G., Wheeler, M.A. and Quintana, F.J. (2022) Func-tion and Therapeutic Value of Astrocytes in Neurological Diseases. Nature Reviews Drug Discovery, 21, 339-358. [Google Scholar] [CrossRef] [PubMed]
|
|
[22]
|
Lee, K.M., Bang, J., Kim, B.Y., et al. (2015) Fructus Mume Al-leviates Chronic Cerebral Hypoperfusion-Induced White Matter and Hippocampal Damage via Inhibition of Inflammation and Downregulation of TLR4 and P38 MAPK Signaling. BMC Complementary and Alternative Medicine, 15, Article No. 125. [Google Scholar] [CrossRef] [PubMed]
|
|
[23]
|
Anderson, M.F., Blomstrand, F., Blomstrand, C., et al. (2003) Astrocytes and Stroke: Networking for Survival? Neurochemical Research, 28, 293-305. [Google Scholar] [CrossRef]
|
|
[24]
|
Boespflug, E.L., Simon, M.J., Leonard, E., et al. (2018) Targeted Assessment of Enlargement of the Perivascular Space in Alzheimer’s Disease and Vascular Dementia Subtypes Impli-cates Astroglial Involvement Specific to Alzheimer’s Disease. Journal of Alzheimer’s Disease, 66, 1587-1597. [Google Scholar] [CrossRef]
|
|
[25]
|
Nagahara, A.H. and Tuszynski, M.H. (2011) Potential Therapeutic Uses of BDNF in Neurological and Psychiatric Disorders. Nature Reviews Drug Discovery, 10, 209-219. [Google Scholar] [CrossRef] [PubMed]
|
|
[26]
|
Chen, A.Q., Fang, Z., Chen, X.L., et al. (2019) Microglia-Derived TNF-α Mediates Endothelial Necroptosis Aggravating Blood Brain-Barrier Disruption after Ischemic Stroke. Cell Death & Dis-ease, 10, Article No. 487. [Google Scholar] [CrossRef] [PubMed]
|
|
[27]
|
Davalos, D., Ryu, J.K., Merlini, M., et al. (2012) Fibrino-gen-Induced Perivascular Microglial Clustering Is Required for the Development of Axonal Damage in Neuroinflamma-tion. Nature Communications, 3, Article No. 1227. [Google Scholar] [CrossRef] [PubMed]
|
|
[28]
|
Yao, X., Liu, S., Ding, W., et al. (2017) TLR4 Signal Ablation Attenu-ated Neurological Deficits by Regulating Microglial M1/M2 Phenotype after Traumatic Brain Injury in Mice. Journal of Neuroimmunology, 310, 38-45. [Google Scholar] [CrossRef] [PubMed]
|
|
[29]
|
Parkhurst, C.N., Yang, G., Ninan, I., et al. (2013) Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor. Cell, 155, 1596-1609. [Google Scholar] [CrossRef] [PubMed]
|
|
[30]
|
Park, J.S., Kam, T.I., Lee, S., et al. (2021) Blocking Microglial Ac-tivation of Reactive Astrocytes Is Neuroprotective in Models of Alzheimer’s Disease. Acta Neuropathologica Commu-nications, 9, Article No. 78. [Google Scholar] [CrossRef] [PubMed]
|
|
[31]
|
Ma, J., Bo, S, H., Lu, X, T., et al. (2016) Protective Effects of Carnosine on White Matter Damage Induced by Chronic Cerebral Hypoperfusion. Neural Regeneration Research, 11, 1438-1444. [Google Scholar] [CrossRef] [PubMed]
|
|
[32]
|
顾雨铖, 徐运. 脑小血管病与血管性认知损害: 关注神经影像学[J]. 国际脑血管病杂志, 2017, 25(3): 244-250.
|
|
[33]
|
Malferrari, G., Bertolino, C., Casoni, F., et al. (2007) The Eligible Study: Ultrasound Assessment in Acute Ischemic Stroke within 3 Hours. Cerebrovascular Diseases, 24, 469-476. [Google Scholar] [CrossRef] [PubMed]
|
|
[34]
|
Sachdev, P., Kalaria, R., O’Brien, J., et al. (2014) Diagnostic Criteria for Vascular Cognitive Disorders: A VASCOG Statement. Alzheimer Disease & Associated Disorders, 28, 206-218. [Google Scholar] [CrossRef]
|
|
[35]
|
Carnevale, L. and Lembo, G. (2019) Innovative MRI Techniques in Neuroimaging Approaches for Cerebrovascular Diseases and Vascular Cognitive Impairment. Inter-national Journal of Molecular Sciences, 20, Article No. 2656. [Google Scholar] [CrossRef] [PubMed]
|
|
[36]
|
Du, J. and Xu, Q. (2019) Neuroimaging Studies on Cognitive Impair-ment Due to Cerebral Small Vessel Disease. Stroke and Vascular Neurology, 4, 99-101. [Google Scholar] [CrossRef] [PubMed]
|
|
[37]
|
杨丹, 徐运. 弥散张量成像和静息态功能磁共振在脑白质损伤相关性认知障碍早期诊断中的作用[J]. 华西医学, 2019, 34(10): 1087-1090.
|
|
[38]
|
Fruhwirth, V., Enzinger, C., Fandler-Höfler, S., et al. (2021) Baseline White Matter Hyperintensities Affect the Course of Cognitive Function after Small Vessel Disease-Related Stroke: A Prospective Observational Study. European Journal of Neurology, 28, 401-410. [Google Scholar] [CrossRef] [PubMed]
|
|
[39]
|
Wardlaw, J.M., Smith, E.E., Biessels, G.J., et al. (2013) Neuroimaging Standards for Research into Small Vessel Disease and Its Contribution to Ageing and Neurodegeneration. The Lancet Neurology, 12, 822-838. [Google Scholar] [CrossRef]
|
|
[40]
|
Benjamin, P., Trippier, S., Lawrence, A.J., et al. (2018) La-cunar Infarcts, but Not Perivascular Spaces, Are Predictors of Cognitive Decline in Cerebral Small-Vessel Disease. Stroke, 49, 586-593. [Google Scholar] [CrossRef]
|
|
[41]
|
Akoudad, S., Wolters, F.J., Viswanathan, A., et al. (2016) Association of Cerebral Microbleeds with Cognitive Decline and Dementia. JAMA Neurology, 73, 934-943. [Google Scholar] [CrossRef] [PubMed]
|
|
[42]
|
Charidimou, A., Shakeshaft, C. and Werring, D.J. (2012) Cere-bral Microbleeds on Magnetic Resonance Imaging and Anticoagulant-Associated Intracerebral Hemorrhage Risk. Fron-tiers in Neurology, 3, Article 133. [Google Scholar] [CrossRef] [PubMed]
|
|
[43]
|
Debette, S., Schilling, S., Duperron, M.G., et al. (2019) Clinical Significance of Magnetic Resonance Imaging Markers of Vascular Brain Injury: A Systematic Review and Me-ta-Analysis. JAMA Neurology, 76, 81-94. [Google Scholar] [CrossRef] [PubMed]
|
|
[44]
|
林霖. 皮质下缺血性血管病患者的扩散张量成像分析和认知功能相关研究[D]: [硕士学位论文]. 福州: 福建医科大学, 2014.
|
|
[45]
|
潘永进, 曹茂红, 周树虎, 等. 皮质下缺血性血管性痴呆患者大脑联络纤维弥散张量成像研究[J]. 脑与神经疾病杂志, 2015(2): 101-105.
|
|
[46]
|
衣立业. 皮层下血管型轻度认知功能障碍的多模态磁共振研究[D]: [硕士学位论文]. 哈尔滨: 哈尔滨医科大学, 2012.
|
|
[47]
|
Frantellizzi, V., Conte, M. and De Vincentis, G. (2021) Hybrid Imaging of Vascular Cognitive Impairment. Seminars in Nuclear Medicine, 51, 286-295. [Google Scholar] [CrossRef] [PubMed]
|
|
[48]
|
Feng, L., Isaac, V., Sim, S., et al. (2013) Associations between Elevated Homocysteine, Cognitive Impairment, and Reduced White Matter Volume in Healthy Old Adults. The American Journal of Geriatric Psychiatry, 21, 164-172. [Google Scholar] [CrossRef] [PubMed]
|
|
[49]
|
Kuo, H.K., Yen, C.J., Chang, C.H., et al. (2005) Relation of C-Reactive Protein to Stroke, Cognitive Disorders, and Depression in the General Population: Systematic Review and Meta-Analysis. The Lancet Neurology, 4, 371-380. [Google Scholar] [CrossRef]
|
|
[50]
|
陈粤瑛, 宋晓楠, 杨树龙. 炎症相关因子在血管性痴呆发病机制中的作用[J]. 中国生物化学与分子生物学报, 2019, 35(7): 693-699.
|
|
[51]
|
Dao, E., Hsiung, G.Y., Sossi, V., et al. (2015) Exploring the Effects of Coexisting Amyloid in Subcortical Vascular Cognitive Impairment. BMC Neurolo-gy, 15, Article No. 197. [Google Scholar] [CrossRef] [PubMed]
|
|
[52]
|
方宇, 张璐, 朱红灿, 等. 脑脊液磷酸化Tau蛋白及β淀粉样蛋白检测在老年期痴呆患者早期鉴别诊断中的价值[J]. 中国老年学杂志, 2011, 31(13): 2561-2562.
|
|
[53]
|
Ravaglia, S., Bini, P., Sinforiani, E., et al. (2008) Cerebrospinal Fluid Levels of Tau Phosphorylated at Threonine 181 in Patients with Alzheimer’s Disease and Vascular Dementia. Neurological Sciences, 29, 417-423. [Google Scholar] [CrossRef] [PubMed]
|
|
[54]
|
Tucek, S. (1984) Problems in the Organization and Control of Acetylcholine Synthesis in Brain Neurons. Progress in Biophysics and Molecular Biology, 44, 1-46. [Google Scholar] [CrossRef] [PubMed]
|
|
[55]
|
周广安, 王安民. 依达拉奉对血管性痴呆患者脑脊液中乙酰胆碱和胆碱含量的影响[J]. 社区医学杂志, 2012, 10(2): 10-11.
|
|
[56]
|
Fanning, J.P., Wong, A.A. and Fraser, J.F. (2014) The Epidemiology of Silent Brain Infarction: A Systematic Review of Population-Based Cohorts. BMC Medicine, 12, Article No. 119. [Google Scholar] [CrossRef] [PubMed]
|
|
[57]
|
Strachan, M.W. (2011) R D Lawrence Lec-ture 2010. The Brain as a Target Organ in Type 2 Diabetes: Exploring the Links with Cognitive Impairment and Dementia. Diabetic Medicine, 28, 141-147. [Google Scholar] [CrossRef] [PubMed]
|
|
[58]
|
Almaguer-Melian, W., Cruz-Aguado, R., Riva Cde, L., et al. (2005) Effect of LTP-Reinforcing Paradigms on Neurotransmitter Release in the Dentate Gyrus of Young and Aged Rats. Biochemical and Biophysical Research Communications, 327, 877-883. [Google Scholar] [CrossRef] [PubMed]
|
|
[59]
|
Xu, G., Zhang, H., Zhang, S., et al. (2008) Plasma Fibrinogen Is Associated with Cognitive Decline and Risk for Dementia in Patients with Mild Cognitive Impairment. International Journal of Clinical Practice, 62, 1070-1075. [Google Scholar] [CrossRef] [PubMed]
|
|
[60]
|
Folsom, A.R., Nambi, V., Bell, E.J., et al. (2013) Troponin T, N-Terminal Pro-B-Type Natriuretic Peptide, and Incidence of Stroke: The Atherosclerosis Risk in Communities Study. Stroke, 44, 961-967. [Google Scholar] [CrossRef]
|
|
[61]
|
张华, 左军杰, 刘顺达, 等. 血浆生长抑素与血管性痴呆的发病部位及其特点的相关性研究[J]. 中华脑血管病杂志(电子版), 2011, 5(6): 488-493.
|
|
[62]
|
陈伟. 血管性痴呆患者血清生长抑素、精氨酸加压素的含量变化及其临床意义[J]. 中风与神经疾病杂志, 2012, 29(12): 1115-1116.
|
|
[63]
|
Pettigrew, C. and Soldan, A. (2019) Defining Cognitive Reserve and Implications for Cognitive Aging. Current Neurology and Neuroscience Reports, 19, Article No. 1. [Google Scholar] [CrossRef] [PubMed]
|
|
[64]
|
Dichgans, M. and Zietemann, V. (2012) Prevention of Vascular Cognitive Impairment. Stroke, 43, 3137-3146. [Google Scholar] [CrossRef]
|
|
[65]
|
张立, 赵小娟, 张继瑶, 等. 脑卒中后认知障碍康复治疗进展[J]. 辽宁中医药大学学报, 2021, 23(11): 179-183.
|
|
[66]
|
Iadecola, C. and Gottesman, R.F. (2019) Neurovascu-lar and Cognitive Dysfunction in Hypertension. Circulation Research, 124, 1025-1044. [Google Scholar] [CrossRef]
|
|
[67]
|
李森, 徐万鹏. 他汀类药物治疗血管性认知障碍的Meta分析[J]. 中国组织工程研究, 2013(50): 8769-8774.
|
|
[68]
|
刘小梅, 陶琼瑶, 陈治秀, 等. 糖尿病认知障碍影响因素的研究进展[J]. 基层医学论坛, 2021, 25(19): 2785-2786.
|
|
[69]
|
Broe, G.A., Grayson, D.A., Creasey, H.M., et al. (2000) Anti-Inflammatory Drugs Protect against Alzheimer Disease at Low Doses. Archives of Neurology, 57, 1586-1591. [Google Scholar] [CrossRef] [PubMed]
|
|
[70]
|
凌佳, 张宗奇, 李清华, 等. 治疗血管性认知障碍的中药有效成分研究进展[J]. 临床内科杂志, 2021, 38(11): 734-737.
|
|
[71]
|
贾建平, 陈生弟. 神经病学[M]. 第8版. 北京: 人民卫生出版社, 2018: 234.
|
|
[72]
|
杨志杰, 高宗恩, 张立功, 等. 支架成形术对伴轻度认知损害的无症状性颈内动脉重度狭窄患者认知功能的影响[J]. 中国现代神经疾病杂志, 2019, 19(10): 743-748.
|
|
[73]
|
Tani, N., Yaegaki, T., Nishino, A., et al. (2018) Functional Connectivity Analysis and Prediction of Cognitive Change after Carot-id Artery Stenting. Journal of Neurosurgery, 131, 1709-1715. [Google Scholar] [CrossRef]
|
|
[74]
|
Guillaume, D.J., Doolittle, N.D., Gahramanov, S., et al. (2010) In-tra-Arterial Chemotherapy with Osmotic Blood-Brain Barrier Disruption for Aggressive Oligodendroglial Tumors: Re-sults of a Phase I Study. Neurosurgery, 66, 48-58; Discussion 58.
|
|
[75]
|
Chida, K., Ogasawara, K., Suga, Y., et al. (2009) Postoperative Cortical Neural Loss Associated with Cerebral Hyperperfusion and Cognitive Impairment after Ca-rotid Endarterectomy: 123I-Iomazenil SPECT Study. Stroke, 40, 448-453. [Google Scholar] [CrossRef]
|
|
[76]
|
余盼, 唐纯志. 基于数据挖掘技术分析针灸治疗血管性认知障碍的选穴规律[J]. 广州中医药大学学报, 2021, 38(12): 2694-2700.
|
|
[77]
|
王年花, 孙瑞, 章志超, 等. 脑卒中后认知障碍患者高压氧治疗的研究进展[J]. 江苏医药, 2023, 49(11): 1170- 1174.
|
|
[78]
|
李小云, 潘娟. SGB对血管性痴呆患者认知功能的疗效观察[J]. 中国现代药物应用, 2016, 10(19): 40-41.
|