不同压力高压氧治疗重型颅脑创伤后昏迷患者的疗效研究

Effects of Hyperbaric Oxygen at Different Pressures on Coma Patients with Severe Traumatic Brain Injury

摘要: 目的：比较0.16 MPa和0.20 MPa两种压力高压氧治疗对重型颅脑创伤后昏迷者的疗效。方法：回顾性分析78例接受0.16 MPa高压氧治疗和41例接受0.20 MPa高压氧治疗的重型颅脑创伤后昏迷患者，比较两组患者治疗前后GCS评分、ADL评分、GOS评分的变化。结果：两组治疗后评分均有不同程度提高，0.16 MPa治疗组在GCS评分3~4分的极重型患者疗效优于0.20 MPa组(P < 0.05)。结论：0.16 MPa高压氧治疗可提高重型颅脑创伤后昏迷患者，尤其是极重型患者的疗效。

Abstract: Objective: To compare the effects of hyperbaric oxygen (HBO) at 0.16 MPa and 0.20 MPa pressure on coma patients after severe traumatic brain injury. Methods: This is a retrospective analysis. A total of 78 coma patients with severe traumatic brain injury were treated with 0.16 MPa hyperbaric oxygen therapy and 41 patients were treated with 0.20 MPa hyperbaric oxygen therapy. We compared the changes in GCS score, ADL score and GOS score before and after treatment between the two groups. Results: The GCS scores of the two groups increased to varying degrees after treatment, and the curative effect of the 0.16 MPa treatment group was better than that of the 0.20 MPa treatment group in the very severe patients with GCS scores of 3~4 (P < 0.05). Conclusion: 0.16 MPa hyperbaric oxygen therapy can improve the efficacy of coma patients after severe traumatic brain injury, especially for very severe patients.