TyG指数及肥胖评价指标对急性胰腺炎病情及预后评估的研究现状
The Research Status of TyG Index and Obesity Evaluation Index in the Evaluation of the Condition and Prognosis of Acute Pancreatitis
DOI: 10.12677/ACM.2024.142513, PDF,    科研立项经费支持
作者: 何云华*, 施荣杰#, 龚佳佳, 牛雨薇:大理大学第一附属医院消化内科,云南 大理
关键词: 急性胰腺炎肥胖TyG指数肥胖评价指标改良TyG指数Acute Pancreatitis Obesity TyG Index Obesity Evaluation Index Modified TyG Index
摘要: 急性胰腺炎(AP)是一种常见的临床问题,由胰腺炎症引起,大部分急性胰腺炎患者症状较轻,且具有自限性,但严重急性胰腺炎的死亡率较高,治疗成本高,因此,早期诊断和正确的治疗至关重要。近年来,国内外关于预测急性胰腺炎病情严重程度及预后的指标被大量报道,试图通过早期采取准确的诊断手段,并及时采取预防措施,来改善患者的预后,减少病死率。TyG指数及肥胖评价相关指标对急性胰腺炎的病情具有一定的预测价值。本文对近年来国内TyG指数及肥胖评价相关指标对急性胰腺炎病情及预后评估方面的研究进行综述。
Abstract: Acute pancreatitis (AP) is a common clinical problem caused by pancreatic inflammation. Most acute pancreatitis is acute pancreatitis and self-limited, but severe acute pancreatitis has a high mortality rate and high treatment costs. Therefore, early diagnosis and correct treatment are es-sential. In recent years, a large number of indicators for predicting the severity and prognosis of acute pancreatitis have been reported at home and abroad. Attempts are made to improve the prognosis of patients and reduce the mortality rate by taking accurate diagnostic measures at an early stage and taking preventive measures in a timely manner. TyG index and obesity evaluation index have certain predictive value for acute pancreatitis. This article reviews the research on the assessment of the condition and prognosis of acute pancreatitis by TyG index and obesity evaluation indicators in China in recent years.
文章引用:何云华, 施荣杰, 龚佳佳, 牛雨薇. TyG指数及肥胖评价指标对急性胰腺炎病情及预后评估的研究现状[J]. 临床医学进展, 2024, 14(2): 3675-3684. https://doi.org/10.12677/ACM.2024.142513

参考文献

[1] Li, C.L., Jiang, M., Pan, C.Q., et al. (2021) The Global, Regional, and National Burden of Acute Pancreatitis in 204 Countries and Territories, 1990-2019. BMC Gastroenterology, 21, Article No. 332. [Google Scholar] [CrossRef] [PubMed]
[2] Garg, S., et al. (2019) Incidence, Admission Rates, and Predic-tors, and Economic Burden of Adult Emergency Visits for Acute Pancreatitis: Data from the National Emergency De-partment Sample, 2006 to 2012. Journal of Clinical Gastroenterology, 53, 220-225. [Google Scholar] [CrossRef
[3] Banks, P.A., Bollen, T.L., Dervenis, C., et al. (2013) Classification of Acute Pancreatitis—2012: Revision of the Atlanta Classification and Definitions by International Consensus. Gut, 62, 102-111. [Google Scholar] [CrossRef] [PubMed]
[4] Andriushchenko, V.P. and Kunovskyi, V.V. (2016) Multicom-ponent Hyperosmolar Colloidal Solutions as an Effective Component of Infusion Therapy in Patients with Acute Pan-creatitis. Emergency Medicine Australasia, 6, 59-64.
[5] Krishna, S., et al. (2017) The Changing Epidemiology of Acute Pancreatitis Hospitalizations: A Decade of Trends and the Impact of Chronic Pancreatitis. Pancreas, 46, 482-488. [Google Scholar] [CrossRef
[6] Lankisch, P.G., Apte, M. and Banks, P.A. (2015) Acute Pancreatitis. The Lancet, 386, 85-96. [Google Scholar] [CrossRef
[7] 商和振, 唐楠, 陈增银, 等. 重症急性胰腺炎评分量表及诊疗进展[J]. 腹部外科, 2024, 37(1): 32-37.
[8] 郭喆, 关键. 重症急性胰腺炎预防与阻断急诊专家共识[J]. 中国急救医学, 2022, 42(5): 369-379.
[9] 张芳, 朱清, 马小芬, 等. 重症胰腺炎消化内科治疗的临床探讨[C]//国际数字医学会. 2017国际数字医学会数字中医药分会论文集. 南京: 解放军第四五四医院消化内科, 2017: 1.
[10] Chen, Z.P., Huang, H.P., He, X.Y., et al. (2022) Early Continuous Blood Purification Affects TNF-Alpha, IL-1beta, and IL-6 in Patients with Severe Acute Pancreatitis via Inhibiting TLR4 Signaling Pathway. The Kaohsiung Journal of Medical Sciences, 38, 479-485. [Google Scholar] [CrossRef] [PubMed]
[11] 张伟玲, 龚晓兵. 生化指标对急性胰腺炎病情及预后评估的研究现状[J]. 中国现代医生, 2023, 61(14): 136-140.
[12] Ormazabal, V., Nair, S., Elfeky, O., et al. (2018) Association between Insulin Resistance and the Development of Cardiovascular Disease. Car-diovascular Diabetology, 17, Article No. 122. [Google Scholar] [CrossRef] [PubMed]
[13] DeFronzo, R.A., Tobin, J.D. and Andres, R. (1979) Glucose Clamp Technique: A Method for Quantifying Insulin Secretion and Re-sistance. American Journal of Physiology, 237, e214-e223. [Google Scholar] [CrossRef
[14] Borai, A., Livingstone, C. and Ferns, G.A. (2007) The Bi-ochemical Assessment of Insulin Resistance. Annals of Clinical Biochemistry, 44, 324-342. [Google Scholar] [CrossRef] [PubMed]
[15] Bajpai, J., Kumar, R., Sreenivas, V., et al. (2011) Prediction of Chemotherapy Response by PET-CT in Osteosarcoma: Correlation with Histologic Necrosis. Journal of Pediatric Hematology/Oncology, 33, e271-e278. [Google Scholar] [CrossRef
[16] Chueire, V.B. and Muscelli, E. (2021) Effect of Free Fatty Acids on Insulin Secretion, Insulin Sensitivity and Incretin Effect—A Narrative Review. Archives of Endocrinology and Metabolism, 65, 24-31. [Google Scholar] [CrossRef] [PubMed]
[17] Castela, I., Morais, J., Barreiros-Mota, I., et al. (2023) De-creased Adiponectin/Leptin Ratio Relates to Insulin Resistance in Adults with Obesity. American Journal of Physiolo-gy-Endocrinology and Metabolism, 324, e115-e119. [Google Scholar] [CrossRef] [PubMed]
[18] Liakh, I., Proczko-Stepaniak, M., Sledzinski, M., et al. (2022) Serum Free Fatty Acid Levels and Insulin Resistance in Patients Undergoing One-Anastomosis Gastric Bypass. Wideochirurgia I Inne Techniki Maloinwazyjne, 17, 194-198. [Google Scholar] [CrossRef] [PubMed]
[19] 李好杰. 中老年人胰岛素抵抗的早期评估与研究[D]: [硕士学位论文]. 海口: 海南医学院, 2023.
[20] Matthews, D.R., Hosker, J.P., Rudenski, A.S., et al. (1985) Homeostasis Model Assessment: Insulin Resistance and Beta-Cell Function from Fasting Plasma Glucose and Insulin Concentrations in Man. Diabetologia, 28, 412-419. [Google Scholar] [CrossRef
[21] Toro-Huamanchumo, C.J., Urrunaga-Pastor, D., Guarnizo-Poma, M., et al. (2019) Triglycerides and Glucose Index as an Insulin Resistance Marker in a Sample of Healthy Adults. Diabetology Metabolic Syndrome, 13, 272-277. [Google Scholar] [CrossRef] [PubMed]
[22] Singh, B. and Saxena, A. (2010) Surrogate Markers of Insulin Re-sistance: A Review. World Journal of Diabetes, 1, 36-47. [Google Scholar] [CrossRef] [PubMed]
[23] Simental-Mendia, L.E., Rodriguez-Moran, M. and Guerrero-Romero, F. (2008) The Product of Fasting Glucose and Triglycerides as Surrogate for Identifying Insulin Resistance in Apparently Healthy Subjects. Metabolic Syndrome and Related Disorders, 6, 299-304. [Google Scholar] [CrossRef] [PubMed]
[24] Vasques, A.C., Novaes, F.S., De Oliveira, M.S., et al. (2011) TyG Index Performs Better Than HOMA in a Brazilian Population: A Hyperglycemic Clamp Validated Study. Diabetes Research and Clinical Practice, 93, e98-e100. [Google Scholar] [CrossRef] [PubMed]
[25] Jeong, S. and Lee, J.H. (2021) The Verification of the Reliability of a Triglyceride-Glucose Index and Its Availability as an Advanced Tool. Metabolomics, 17, Article No. 97. [Google Scholar] [CrossRef] [PubMed]
[26] Niknam, R., Moradi, J., Jahanshahi, K.A., et al. (2020) Associ-ation between Metabolic Syndrome and Its Components with Severity of Acute Pancreatitis. Diabetes, Metabolic Syn-drome and Obesity, 13, 1289-1296. [Google Scholar] [CrossRef
[27] Shen, Z., Wang, X., Zhen, Z., et al. (2021) Metabolic Syndrome Components and Acute Pancreatitis: A Case-Control Study in China. BMC Gastroenterology, 21, Article No. 17. [Google Scholar] [CrossRef] [PubMed]
[28] Szentesi, A., Parniczky, A., Vincze, A., et al. (2019) Multiple Hits in Acute Pancreatitis: Components of Metabolic Syndrome Synergize Each Other’s Deteriorating Effects. Frontiers in Physiology, 10, Article 1202. [Google Scholar] [CrossRef] [PubMed]
[29] Aune, D., Mahamat-Saleh, Y., Norat, T., et al. (2020) Diabetes Mellitus and the Risk of Pancreatitis: A Systematic Review and Meta-Analysis of Cohort Studies. Pancreatology, 20, 602-607. [Google Scholar] [CrossRef] [PubMed]
[30] Xue, E., Shi, Q., Guo, S., et al. (2022) Preexisting Dia-betes, Serum Calcium and D-Dimer Levels as Predictable Risk Factors for Pancreatic Necrosis of Patients with Acute Pancreatitis: A Retrospective Study. Expert Review of Gastroenterology & Hepatology, 16, 913-921. [Google Scholar] [CrossRef] [PubMed]
[31] Ioannis, P., Pedram, P., Marie, T., et al. (2021) Association of Serum Triglyceride Levels with Severity in Acute Pancreatitis: Results from an International, Multicenter Cohort Study. Digestion, 102, 809-813. [Google Scholar] [CrossRef] [PubMed]
[32] Yang, X., He, J., Ma, S., et al. (2021) The Role of Comorbid Hypertri-glyceridemia and Abdominal Obesity in the Severity of Acute Pancreatitis: A Retrospective Study. Lipids in Health and Disease, 20, Article No. 171. [Google Scholar] [CrossRef] [PubMed]
[33] Huang, Q., Wu, Z., Zhang, Y., et al. (2023) Obesity Exacerbates Acute Gastrointestinal Injury and Intestinal Barrier Dysfunction in Early-Stage Acute Pancreatitis. The Turkish Journal of Gastroenterology: The Official Journal of Turkish Society of Gastroenterology, 34, 421-426. [Google Scholar] [CrossRef] [PubMed]
[34] Placzkowska, S., Pawlik-Sobecka, L., Kokot, I., et al. (2019) Indirect Insulin Resistance Detection: Current Clinical Trends and Laboratory Limitations. Biomedical Papers of the Medical Faculty of the University Palacky, Olomouc, Czech Republic, 163, 187-199. [Google Scholar] [CrossRef] [PubMed]
[35] Cho, S.K., Huh, J.H., Yoo, J.S., et al. (2019) HOMA-Estimated Insulin Resistance as an Independent Prognostic Factor in Patients with Acute Pancreatitis. Scientific Reports, 9, Article No. 14894. [Google Scholar] [CrossRef] [PubMed]
[36] Mosztbacher, D., Hanak, L., Farkas, N., et al. (2020) Hypertri-glyceridemia-Induced Acute Pancreatitis: A Prospective, Multicenter, International Cohort Analysis of 716 Acute Pan-creatitis Cases. Pancreatology, 20, 608-616. [Google Scholar] [CrossRef] [PubMed]
[37] Nagy, A., Juhasz, M.F., Gorbe, A., et al. (2021) Glucose Levels Show Independent and Dose-Dependent Association with Worsening Acute Pancreatitis Outcomes: Post-Hoc Analysis of a Prospective, International Cohort of 2250 Acute Pancreatitis Cases. Pancreatology, 21, 1237-1246. [Google Scholar] [CrossRef] [PubMed]
[38] Leung, P.S. and Chan, Y.C. (2009) Role of Oxidative Stress in Pancreatic Inflammation. Antioxidants & Redox Signaling, 11, 135-165. [Google Scholar] [CrossRef] [PubMed]
[39] McCracken, E., Monaghan, M. and Sreenivasan, S. (2018) Patho-physiology of the Metabolic Syndrome. Clinics in Dermatology, 36, 14-20. [Google Scholar] [CrossRef] [PubMed]
[40] 陈旭, 马佳丽, 周玉玲, 等. 甘油三酯-葡萄糖指数对急性胰腺炎严重程度的早期预测价值[J]. 中日友好医院学报, 2021, 35(5): 280-283.
[41] Cho, S.K., Jung, S., Lee, K.J., et al. (2018) Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio Can Predict the Severity of Gall-stone Pancreatitis. BMC Gastroenterology, 18, Article No. 18. [Google Scholar] [CrossRef] [PubMed]
[42] Park, J.M., Shin, S.P., Cho, S.K., et al. (2020) Triglyceride and Glucose (TyG) Index Is an Effective Biomarker to Identify Severe Acute Pancreatitis. Pancreatology, 20, 1587-1591. [Google Scholar] [CrossRef] [PubMed]
[43] 樊潇潇, 肖华, 朱炳喜. TyG指数联合NLR对急性胰腺炎严重程度的预测价值. 医学研究杂志, 2023, 52(4): 133-138.
[44] 李书贺. 甘油三酯葡萄糖指数对急性胰腺炎严重程度的预测价值[D]: [硕士学位论文]. 乌鲁木齐: 新疆医科大学, 2023.
[45] 王惠雨. TyG-BMI指数、α-HBDH对急性胰腺炎严重程度的预测价值[D]: [硕士学位论文]. 兰州: 兰州大学, 2023.
[46] 李光耀, 韩菲, 姜鑫, 等. 甘油三酯葡萄糖指数在急性胰腺炎评估中的应用价值[J]. 胃肠病学和肝病学杂志, 2022, 31(6): 619-624.
[47] 魏怡敏. 甘油三酯葡萄糖指数评估急性胰腺炎严重程度的临床研究[D]: [硕士学位论文]. 济南: 山东大学, 2022.
[48] 满加美. TyG指数在急性胰腺炎严重程度评估中的价值[D]: [硕士学位论文]. 大理: 大理大学, 2022.
[49] Wei, Y. and Guo, J. (2023) High Triglyceride-Glucose Index Is Associated with Poor Prognosis in Patients with Acute Pancre-atitis. Digestive Diseases and Sciences, 68, 978-987. [Google Scholar] [CrossRef] [PubMed]
[50] Song, K., Park, G., Lee, H.S., et al. (2021) Prediction of Insulin Resistance by Modified Triglyceride Glucose Indices in Youth. Life (Basel), 11, Article 286. [Google Scholar] [CrossRef] [PubMed]
[51] Zheng, S., Shi, S., Ren, X., et al. (2016) Triglyceride Glucose-Waist Circumference, a Novel and Effective Predictor of Diabetes in First-Degree Relatives of Type 2 Diabetes Patients: Cross-Sectional and Prospective Cohort Study. Journal of Translational Medicine, 14, Article No. 260. [Google Scholar] [CrossRef] [PubMed]
[52] Khan, S.H., Sobia, F., Niazi, N.K., et al. (2018) Metabolic Clustering of Risk Factors: Evaluation of Triglyceride-Glucose Index (TyG Index) for Evaluation of Insulin Resistance. Diabetology Metabolic Syndrome, 10, Article No. 74. [Google Scholar] [CrossRef] [PubMed]
[53] Er, L.K., Wu, S., Chou, H.H., et al. (2016) Triglyceride Glu-cose-Body Mass Index Is a Simple and Clinically Useful Surrogate Marker for Insulin Resistance in Nondiabetic Indi-viduals. PLOS ONE, 11, e149731. [Google Scholar] [CrossRef] [PubMed]
[54] Khamseh, M.E., Malek, M., Abbasi, R., et al. (2021) Triglyc-eride Glucose Index and Related Parameters (Triglyceride Glucose-Body Mass Index and Triglyceride Glucose-Waist Circumference) Identify Nonalcoholic Fatty Liver and Liver Fibrosis in Individuals with Overweight/Obesity. Metabolic Syndrome and Related Disorders, 19, 167-173. [Google Scholar] [CrossRef] [PubMed]
[55] Martinez-Iglesias, O., Naidoo, V., Cacabelos, N., et al. (2021) Epi-genetic Biomarkers as Diagnostic Tools for Neurodegenerative Disorders. International Journal of Molecular Sciences, 23, Article 13. [Google Scholar] [CrossRef] [PubMed]
[56] Sheng, G., Lu, S., Xie, Q., et al. (2021) The Usefulness of Obesity and Lipid-Related Indices to Predict the Presence of Non-Alcoholic Fatty Liver Disease. Lipids in Health and Disease, 20, Article No. 134. [Google Scholar] [CrossRef] [PubMed]
[57] (2000) Obesity: Preventing and Managing the Global Epidemic. Report of a WHO Consultation. World Health Organization Technical Report Series, 894, 1-253.
[58] Arvanitakis, M., Gkolfakis, P. and Fernandez, Y.V.M. (2021) Nutrition in Acute Pancreatitis. Current Opinion in Clinical Nutrition & Metabolic Care, 24, 428-432. [Google Scholar] [CrossRef
[59] Lee, P.J., Lahooti, A., Culp, S., et al. (2023) Obesity and Alcoholic Etiology as Risk Factors for Multisystem Organ Failure in Acute Pancreatitis: Multinational Study. United European Gastroenterology Journal, 11, 383-391. [Google Scholar] [CrossRef] [PubMed]
[60] McGuire, S.P., Keller, S.L., Maatman, T.K., et al. (2022) Obesity Worsens Local and Systemic Complications of Necrotizing Pancreatitis and Prolongs Disease Course. Journal of Gas-trointestinal Surgery, 26, 2128-2135. [Google Scholar] [CrossRef] [PubMed]
[61] Shin, K.Y., Lee, W.S., Chung, D.W., et al. (2011) Influence of Obesity on the Severity and Clinical Outcome of Acute Pancreatitis. Gut and Liver, 5, 335-339. [Google Scholar] [CrossRef] [PubMed]
[62] Sakai, N.S., Taylor, S.A. and Chouhan, M.D. (2018) Obesity, Metabolic Disease and the Pancreas-Quantitative Imaging of Pancreatic Fat. The British Journal of Radiology, 91, Article 20180267. [Google Scholar] [CrossRef] [PubMed]
[63] Fain, J.N., Madan, A.K., Hiler, M.L., et al. (2004) Comparison of the Release of Adipokines by Adipose Tissue, Adipose Tissue Matrix, and Adipocytes from Visceral and Subcutaneous Abdominal Adipose Tissues of Obese Humans. Endocrinology, 145, 2273-2282. [Google Scholar] [CrossRef] [PubMed]
[64] Li, Z., Yu, X., Werner, J., et al. (2019) The Role of Interleukin-18 in Pancreatitis and Pancreatic Cancer. Cytokine & Growth Factor Reviews, 50, 1-12. [Google Scholar] [CrossRef] [PubMed]
[65] Hegyi, P., Szakacs, Z. and Sahin-Toth, M. (2020) Lipotoxicity and Cytokine Storm in Severe Acute Pancreatitis and COVID-19. Gastroenterology, 159, 824-827. [Google Scholar] [CrossRef] [PubMed]
[66] Noel, P., Patel, K., Durgampudi, C., et al. (2016) Peripancreatic Fat Necrosis Worsens Acute Pancreatitis Independent of Pancreatic Necrosis via Unsaturated Fatty Acids Increased in Human Pancreatic Necrosis Collections. Gut, 65, 100-111. [Google Scholar] [CrossRef] [PubMed]
[67] Khatua, B., El-Kurdi, B. and Singh, V.P. (2017) Obesity and Pancreatitis. Current Opinion in Gastroenterology, 33, 374-382. [Google Scholar] [CrossRef
[68] Panek, J., Sztefko, K. and Drozdz, W. (2001) Composition of Free Fatty Acid and Triglyceride Fractions in Human Necrotic Pancreatic Tissue. Medical Science Monitor, 7, 894-898.
[69] Patel, K., Trivedi, R.N., Durgampudi, C., et al. (2015) Lipolysis of Visceral Adipocyte Triglyceride by Pancreatic Lipases Converts Mild Acute Pancreatitis to Severe Pancreatitis Independent of Necrosis and Inflammation. The American Journal of Pathology, 185, 808-819. [Google Scholar] [CrossRef] [PubMed]
[70] Navina, S., Acharya, C., DeLany, J.P., et al. (2011) Lipotoxicity Causes Multisystem Organ Failure and Exacerbates Acute Pan-creatitis in Obesity. Science Translational Medicine, 3, 107ra110. [Google Scholar] [CrossRef] [PubMed]
[71] Zheng, Z.X., Bi, J.T., Cai, X., et al. (2022) The Clinical Sig-nificance of Body Mass Index in the Early Evaluation of Acute Biliary Pancreatitis. Heliyon, 8, e12003. [Google Scholar] [CrossRef] [PubMed]
[72] 王贤柱, 王梓阳, 赖奕辉, 等. 体重指数与急性胰腺炎患者严重程度及预后相关性的Meta分析[J]. 中国医药科学, 2021, 11(10): 31-35.
[73] Lam, B.C., Koh, G.C., Chen, C., et al. (2015) Comparison of Body Mass Index (BMI), Body Adiposity Index (BAI), Waist Circumference (WC), Waist-to-Hip Ratio (WHR) and Waist-to-Height Ratio (WHtR) as Predictors of Cardiovascular Disease Risk Factors in an Adult Population in Singapore. PLOS ONE, 10, e122985. [Google Scholar] [CrossRef] [PubMed]
[74] Fan, Y., He, D., Liu, S., et al. (2021) Association between Visceral Adipose Index and Risk of Hypertension in a Middle-Aged and Elderly Chinese Population. Nutrition, Me-tabolism and Cardiovascular Diseases, 31, 2358-2365. [Google Scholar] [CrossRef] [PubMed]
[75] 王强梅. 肥胖评价指标VAI、LAP和BRI对2型糖尿病发病的预测价值[D]: [硕士学位论文]. 兰州: 兰州大学, 2021.
[76] Sadr-Azodi, O., Orsini, N., Andren-Sandberg, A., et al. (2013) Abdominal and Total Adiposity and the Risk of Acute Pancreatitis: A Population-Based Prospective Cohort Study. American Journal of Gastroenterology, 108, 133-139. [Google Scholar] [CrossRef] [PubMed]
[77] Sawalhi, S., Al-Maramhy, H., Abdelrahman, A.I., et al. (2014) Does the Presence of Obesity and/or Metabolic Syndrome Affect the Course of Acute Pancreatitis?: A Prospective Study. Pancreas, 43, 565-570. [Google Scholar] [CrossRef
[78] Aune, D., Mahamat-Saleh, Y., Norat, T., et al. (2021) High Body Mass Index and Central Adiposity Is Associated with Increased Risk of Acute Pancreatitis: A Meta-Analysis. Digestive Diseases and Sciences, 66, 1249-1267. [Google Scholar] [CrossRef] [PubMed]
[79] Ge, Q., Qi, Z., Xu, Z., et al. (2021) Comparison of Different Obesity Indices Related with Hypertension among Different Sex and Age Groups in China. Nutrition, Metabolism and Cardiovascular Diseases, 31, 793-801. [Google Scholar] [CrossRef] [PubMed]
[80] Kotsis, V., Nilsson, P., Grassi, G., et al. (2015) New Devel-opments in the Pathogenesis of Obesity-Induced Hypertension. Journal of Hypertension, 33, 1499-1508. [Google Scholar] [CrossRef
[81] 王志洋. 腰围身高比值对早期预测急性胰腺炎严重程度的价值[D]: [硕士学位论文]. 南昌: 南昌大学, 2020.
[82] Amato, M.C., Giordano, C., Galia, M., et al. (2010) Vis-ceral Adiposity Index: A Reliable Indicator of Visceral Fat Function Associated with Cardiometabolic Risk. Diabetes Care, 33, 920-922. [Google Scholar] [CrossRef] [PubMed]
[83] Yashima, Y., Isayama, H., Tsujino, T., et al. (2011) A Large Volume of Visceral Adipose Tissue Leads to Severe Acute Pancreatitis. Journal of Gastroenterology, 46, 1213-1218. [Google Scholar] [CrossRef] [PubMed]
[84] Xia, W., Yu, H., Huang, Y., et al. (2022) The Vis-ceral Adiposity Index Predicts the Severity of Hyperlipidaemic Acute Pancreatitis. Internal and Emergency Medicine, 17, 417-422. [Google Scholar] [CrossRef] [PubMed]
[85] 王婷婷. 内脏脂肪指数在急性胰腺炎病情严重程度及预后评估中的价值[D]: [硕士学位论文]. 大连: 大连医科大学, 2022.
[86] Henry, K. (2006) Correction: The “Lipid Accumulation Product” Performs Better Than the Body Mass Index for Recognizing Cardiovascular Risk: A Population-Based Comparison. BMC Cardiovascular Disorders, 6, Article No. 5. [Google Scholar] [CrossRef
[87] 段绍杰, 刘尊敬, 陈佳良, 等. 脂质蓄积指数、内脏脂肪指数对非酒精性脂肪性肝病的预测价值[J]. 临床肝胆病杂志, 2022, 38(1): 129-134.
[88] Krakauer, N.Y. and Krakauer, J.C. (2012) A New Body Shape Index Predicts Mortality Hazard Independently of Body Mass Index. PLOS ONE, 7, e39504. [Google Scholar] [CrossRef] [PubMed]
[89] Guerrero-Romero, F. and Rodriguez-Moran, M. (2003) Abdominal Volume Index. An Anthropometry-Based Index for Estimation of Obesity Is Strongly Related to Impaired Glucose Tolerance and Type 2 Diabetes Mellitus. Archives of Medical Research, 34, 428-432. [Google Scholar] [CrossRef
[90] Thomas, D.M., Bredlau, C., Bosy-Westphal, A., et al. (2013) Relationships between Body Roundness with Body Fat and Visceral Adipose Tissue Emerging from a New Geometrical Model. Obesity (Silver Spring), 21, 2264-2271. [Google Scholar] [CrossRef] [PubMed]
[91] Ye, J., Hu, Y., Chen, X., et al. (2023) Association between the Weight-Adjusted Waist Index and Stroke: A Cross- Sectional Study. BMC Public Health, 23, Article No. 1689. [Google Scholar] [CrossRef] [PubMed]