特鲁索综合征一例并文献复习
Trousseau Syndrome: A Case Report and Literature Review
摘要: 特鲁索综合征(Trousseau syndrome, TS)是一种恶性肿瘤引发体内高凝状态导致血栓栓塞的临床表现,目前发病机制尚未明确,可与恶性肿瘤相继发生,患者易反复发作脑区多血管梗死,D-二聚体水平异常升高,治疗上多给予低分子肝素抗凝,预后多不良。本文报道1例突发脑梗死的肺癌患者病例,并结合相关文献,探讨该病抗肿瘤治疗改善预后的价值,以期提高临床医生对特鲁索综合征的诊疗水平,尽早发现并积极治疗原发病,使患者生存获益。
Abstract: Trousseau syndrome (TS) is a clinical manifestation of thromboembolism caused by hypercoagu-lability in vivo caused by malignant tumor. At present, the pathogenesis is not clear, and it can oc-cur one after another with malignant tumor. Patients are prone to recurrent multi-vessel infarction in the brain area, and the level of D-dimer is abnormally elevated. Low molecular weight heparin is often given for anticoagulation in treatment, resulting in poor prognosis. This paper reports a case of lung cancer with sudden cerebral infarction, and discusses the value of anti-tumor therapy to im-prove the prognosis of the disease, in order to improve the level of clinical diagnosis and treatment of Trousseau syndrome, find and actively treat the primary disease as soon as possible, and benefit the survival of patients.
文章引用:王乐乐, 张传涛, 侯和磊, 张晓春. 特鲁索综合征一例并文献复习[J]. 临床医学进展, 2024, 14(2): 3885-3889. https://doi.org/10.12677/ACM.2024.142540

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