血常规、降钙素原、血沉、超敏C反应蛋白及血清淀粉样蛋白在布氏杆菌病临床诊断中应用价值的研究

Study on the Application Value of Routine Blood Count, Procalcitonin, Erythrocyte Sedimentation Rate, Hypersensitive C-Reactive Protein and Serum Amyloid in the Clinical Diagnosis of Brucellosis

摘要: 目的：分析探讨血常规、降钙素原、血沉、超敏C反应蛋白(CRP)及血清淀粉样蛋白(SAA)在布氏杆菌病诊断过程中的应用价值。方法：收集我院2021年1月~2023年12月确诊为布病患者(血培养阳性) 42例的临床病例的血常规、降钙素原、血沉、超敏C反应蛋白(CRP)及血清淀粉样蛋白(SAA)等检验指标。用电阻抗法检测血常规，化学发光法专用试剂盒检测血浆PCT，放射免疫比浊法检测超敏C反应蛋白(CRP)和血清淀粉样蛋白(SAA)，倾斜管法检测血沉。结果：布病患者的白细胞、红细胞、血小板、降钙素原水平基本正常，淋巴细胞比率、血沉、CRP、SAA有增加的趋势，中性粒细胞比率有降低的趋势。

Abstract: Objective: To analyze the application value of routine blood test, procalcitonin, ESR, hypersensitive C-reactive protein (CRP) and serum amyloid (SAA) in the diagnosis of brucellosis. Methods: The blood routine, procalcitonin, erythrocyte sedimentation rate, hypersensitive C-reactive protein (CRP) and serum amyloid (SAA) of 42 clinical patients diagnosed with brucellosis (positive blood culture) in our hospital from January 2021 to December 2023 were collected. Routine blood tests were performed by electrical impedance method, plasma PCT was detected by a special kit for chemiluminescence method, hypersensitive C-reactive protein (CRP) and serum amyloid (SAA) were detected by radioimmunoturbidimetry, and ESR was detected by tilt tube method. Results: The levels of white blood cells, red blood cells, platelets, and procalcitonin were basically normal, and the lymphocyte ratio, erythrocyte sedimentation rate, CRP, and SAA increased, and the neu-trophil ratio decreased.