脊柱结核术后复发危险因素的研究进展

Research Progress on Risk Factors of Postoperative Recurrence of Spinal Tuberculosis

摘要: 脊柱结核是全世界范围内发病率较高的疾病，对于病情较重或合并有并发症的脊柱结核患者，手术治疗是第一选择。脊柱结核病灶清除植骨融合内固定作为目前公认的治疗脊柱结核的手术方法，其治疗效果得到了越来越多的认可，内固定的广泛应用更使得脊柱结核的治疗效果大大提高。但由于结核病具有难治性和易复发性等特点，以及耐药菌株的出现、不规律化疗或病灶清除不彻底等原因，脊柱结核手术治疗后结核病灶复发率仍较高，复发作为脊柱结核患者术后较为常见的并发症之一，该并发症的发生意味着患者要再次经历手术，延长病程。本文重点讨论影响脊柱结核术后复发的危险因素。

Abstract: Spinal tuberculosis is a disease with a high incidence rate worldwide. Spinal tuberculosis is a dis-ease with a high incidence worldwide. Surgical treatment is the first choice for patients with severe or complicated spinal tuberculosis. Spinal tuberculosis focus debridement, bone graft fusion and internal fixation is currently recognized as a surgical method for the treatment of spinal tuberculo-sis, its therapeutic effect has been more and more recognized, and the wide application of internal fixation has greatly improved the therapeutic effect of spinal tuberculosis. However, because tu-berculosis is difficult to treat and easy to recur, as well as the emergence of drug-resistant strains, irregular chemotherapy or incomplete focus debridement and other reasons, the recurrence rate of spinal tuberculosis after surgical treatment is still high. Recurrence is one of the more common postoperative complications in patients with spinal tuberculosis, which means that patients have to undergo surgery again and prolong the course of the disease. This article focuses on the risk factors of postoperative recurrence of spinal tuberculosis.