不同年龄卒中后癫痫发作的相关影响因素分析

Analysis of Related Influencing Factors of Epilepsy after Stroke at Different Ages

摘要: 目的：分析探讨不同年龄卒中后癫痫发作患者的临床特点，为该病的预防与控制工作提供理论参考。方法：根据不同年龄和是否存在卒中后癫痫发作对1662例卒中患者进行回顾性分析，采用回归分析验证不同年龄卒中后癫痫发作的相关影响因素。结果：1) 卒中后癫痫发作的发生率为14.37%，性别比为1.69:1，年龄22~86 (52.31 ± 16.62)岁。癫痫组与非癫痫组的性别、高血压病史、肺部感染史、病灶部位、病灶范围存在显著统计学差异(P < 0.05)。2) 中青年组与老年组的年龄、高血压病史、心血管病史、肺部感染史、病灶范围存在显著统计学差异(P < 0.05)。3) Logistic回归分析结果显示年龄、高血压病史、心血管病史、肺部感染史、病灶部位、病灶范围与卒中后癫痫发作存在显著关联(P < 0.05)。结论 高龄，有高血压病史、心血管病史、肺部感染史，卒中部位位于皮质、病灶范围大可能是导致卒中后癫痫发作的主要危险因素，在临床实际中对于伴有上述情况的卒中患者应密切关注，积极防治，提高患者生存质量。

Abstract: Objective: To analyze and explore the clinical characteristics of patients with epilepsy after stroke of different ages in Yimeng area, so as to provide theoretical reference for the prevention and control of the disease. Methods: A retrospective analysis of 1662 stroke patients was carried out according to different ages and whether there was post-stroke epilepsy. Regression analysis was used to verify the relevant influencing factors of post-stroke epilepsy in different ages. Results: 1) The incidence of epilepsy after stroke was 14.37%, the sex ratio was 1.69:1, and the age was 22~86 (52.31 ± 16.62) years old. There were significant statistical differences between the epilepsy group and the non-epilepsy group in terms of sex, history of hypertension, history of pulmonary infection, location and scope of focus (P < 0.05). 2) There were significant statistical differences in age, history of hy-pertension, history of cardiovascular disease, history of pulmonary infection and range of lesions between the young and middle-aged groups and the elderly group (P < 0.05). 3) Logistic regression analysis showed that age, history of hypertension, history of cardiovascular disease, history of pul-monary infection, location and scope of focus were significantly associated with post-stroke seizures (P < 0.05). Conclusion: The main risk factors of epilepsy after stroke in Yimeng area may be the el-derly, with a history of hypertension, cardiovascular disease and pulmonary infection, the location of stroke in the cortex, and the large range of focus. In clinical practice, close attention should be paid to stroke patients with the above conditions, active prevention and treatment should be taken to improve the quality of life of patients.