散发型克雅病2例并文献复习
Two Cases Report of Sporadic Creutzfeldt-Jakob Disease and Literature Re-view
DOI: 10.12677/ACM.2024.143666, PDF,   
作者: 张娇娇*, 马爱军#：青岛大学附属医院神经内科，山东 青岛
关键词: 克雅病；朊病毒病；病例报告；Creutzfeldt-Jakob Disease； Prion Disease； Case Report
摘要: 目的：探讨克雅病临床特征及诊断。方法：通过对2例克雅病患者的临床表现、诊断、辅助检查等进行分析，并进行文献复习。结果：克雅病症状不典型，结合患者症状及MR“花边征”及脑脊液14-3-3蛋白做出诊断。结论：克雅病诊断困难，目前尚无有效治疗手段，且预后极差，应被临床医生所重视。
Abstract: Objective: To investigate the clinical features and diagnosis of Creutzfeldt-Jakob disease. Methods: The clinical manifestations, diagnosis and auxiliary examination of two patients with Creutz-feldt-Jakob disease were analyzed and literature review was conducted. Results: The symptoms of Creutzfeldt-Jakob disease were atypical, and the diagnosis was made based on the patient’s symp-toms and MR “lace sign” and cerebrospinal fluid 14-3-3 protein. Conclusion: The diagnosis of Creutzfeldt-Jakob disease is difficult, there is no effective treatment method, and the prognosis is very poor, which should be paid attention to by clinicians.
文章引用：张娇娇, 马爱军. 散发型克雅病2例并文献复习[J]. 临床医学进展, 2024, 14(3): 66-72. https://doi.org/10.12677/ACM.2024.143666

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