以左眼睑下垂为首发症状的SLE一例并文献复习
A Case Report of SLE with Left Blepharoptosis as the First Symptom and Re-view of the Literature
DOI: 10.12677/ACM.2024.143734, PDF,   
作者: 李立娟:大理大学临床医学院,云南 大理;苏 俊*:大理白族自治州人民医院神经外科,云南 大理
关键词: 单侧眼睑下垂免疫异常系统性红斑狼疮病例报告Unilateral Blepharoptosis Immune Abnormality SLE Case Report
摘要: SLE起病隐匿,临床症状多样,早期症状往往不典型。本文报告1例以左眼睑下垂为首发症状的SLE诊治经过。该患者以左眼睑下垂为首发症状,头颅影像学检查未见异常,重症肌无力相关抗体检测阴性,行免疫学相关检查诊断SLE,后经肾上腺皮质激素治疗病情控制。该例的诊治提示,临床工作者应提高对免疫疾病的认识,早期诊断、早期治疗,对改善SLE患者的预后至关重要。
Abstract: The onset of SLE is hidden, the clinical symptoms are various, and the early symptoms are often atypical. This paper reports the diagnosis and treatment of a case of SLE with left blepharoptosis as the first symptom. The patient had left blepharoptosis as the first symptom, no abnormality in cra-nial imaging examination and negative detection of myasthenia gravis-related antibodies. SLE was diagnosed by immunological examination and was controlled by corticosteroid treatment. The di-agnosis and treatment of this case suggest that clinical workers should improve their understand-ing of immune diseases, early diagnosis and early treatment are very important to improve the prognosis of patients with SLE.
文章引用:李立娟, 苏俊. 以左眼睑下垂为首发症状的SLE一例并文献复习[J]. 临床医学进展, 2024, 14(3): 526-530. https://doi.org/10.12677/ACM.2024.143734

参考文献

[1] 李若洁, 叶冬青. 系统性红斑狼疮的全基因组关联研究进展[J]. 中华疾病控制杂志, 2011, 15(7): 614-618.
[2] 胡东艳, 李明. 系统性红斑狼疮病情活动相关因素的研究[J]. 中华皮肤科杂志, 2003(1): 21-24.
[3] Rai, R., Chauhan, S.K., Singh, V.V., et al. (2016) RNA-Seq Analysis Reveals Unique Transcriptome Signatures in Systemic Lupus Erythematosus Patients with Distinct Autoantibody Specificities. PLOS ONE, 11, e0166312. [Google Scholar] [CrossRef] [PubMed]
[4] Durcan, L., O’dwyer, T. and Petri, M. (2019) Management Strategies and Future Directions for Systemic Lupus Erythematosus in Adults. Lancet, 393, 2332-2343. [Google Scholar] [CrossRef
[5] 李静, 高莹莹. 系统性红斑狼疮的眼部表现及治疗进展[J]. 中华临床医师杂志(电子版), 2011, 5(12): 3581-3584.
[6] 谢长好, 李志军. 系统性红斑狼疮的诊断与治疗[J]. 中华全科医学, 2020, 18(4): 527-528.
[7] 席海英. 系统性红斑狼疮患者临床发病特点分析[J]. 中国实用医药, 2011, 6(31): 71-72.
[8] Palejwala, N.V., Walia, H.S. and Yeh, S. (2012) Ocular Manifestations of Systemic Lupus Er-ythematosus: A Review of the Literature. Autoimmune Diseases, 2012, Article ID 290898. [Google Scholar] [CrossRef] [PubMed]
[9] 莫蓉, 刘卫彬, 邱力, 等. 重症肌无力胸腺切除术后伴发系统性红斑狼疮一例报道[J]. 中国神经免疫学和神经病学杂志, 2014, 21(6): 447.
[10] 常婷. 中国重症肌无力诊断和治疗指南(2020版) [J]. 中国神经免疫学和神经病学杂志, 2021, 28(1): 1-12.
[11] 曹思曼, 文军, 宋广梅, 等. SLE伴颅内动脉瘤致右眼睑下垂一例[J]. 新医学, 2023, 54(1): 75-79.
[12] 果海. 以眼睑水肿为突出表现的系统性红斑狼疮1例[J]. 中国实用内科杂志, 1999(4): 39.
[13] 张永文, 沈思钰, 蔡辉. 以眼睑及面部肿胀为首发症状的系统性红斑狼疮1例[J]. 山西医科大学学报, 2009, 40(6): 567-568.
[14] 张炜. SLE的眼眶周围水肿[J]. 国外医学皮肤病学分册, 1984(1): 34.