血清CA125与心力衰竭患者的相关性分析
Correlation Analysis between Serum CA125 and Patients with Heart Failure
DOI: 10.12677/ACM.2024.143738, PDF,   
作者: 茹则古丽·图尔荪*：新疆医科大学第一附属医院，心血管内科，新疆 乌鲁木齐；郑颖颖#：新疆医科大学第一附属医院，新疆 乌鲁木齐
关键词: 血清CA125；心力衰竭；相关性；Serum CA125； Heart Failure； Correlation
摘要: 心血管系统疾病是引起死亡的主要疾病，心力衰竭的发病率呈逐年上升的趋势。心衰治疗越早明确病因，及时干预疾病，对提高治疗效果及患者生活质量有着不容小觑的意义。本文通过介绍心力衰竭背景、现状和CA125的情况，从而进一步探讨血清CA125与心力衰竭患者的相关性分析。期望进一步深入了解血清CA125与心力衰竭患者的关系。
Abstract: Cardiovascular system diseases are the main causes of death, and the incidence of heart failure is increasing year by year. The earlier the cause of heart failure is clarified and the disease is inter-vened in a timely manner, the greater the significance of improving the treatment effect and the patient’s quality of life cannot be underestimated. This article introduces the background, current situation and CA125 status of heart failure to further explore the correlation between serum CA125 and heart failure patients. We hope to further understand the relationship between serum CA125 and patients with heart failure.
文章引用：茹则古丽·图尔荪, 郑颖颖. 血清CA125与心力衰竭患者的相关性分析[J]. 临床医学进展, 2024, 14(3): 555-560. https://doi.org/10.12677/ACM.2024.143738

参考文献

[1] 管惠静, 杜丹, 孙明祎, 等. 四君子汤加减治疗慢性心力衰竭气虚痰瘀证的临床效果[J]. 世界中医药, 2019, 14(7): 1817-1820.
[2] 石娓霞. 温阳活血益心方联合西药治疗慢性心力衰竭的临床观察[J]. 中国民间疗法, 2021, 29(10): 89-92.
[3] 国家心血管病医疗质量控制中心专家委员会心力衰竭专家工作组. 2020中国心力衰竭医疗质量控制报告[J]. 中国循环杂志, 2021, 36(3): 221-238.
[4] Roger, V.L. (2021) Epidemiology of Heart Failure: A Contemporary Perspective. Circulation Research, 128, 1421-1434. [Google Scholar] [CrossRef] 
[5] Zhang, Y.H., Zhang, J., Butler, J., et al. (2017) Contem-porary Epidemiology, Management, and Outcomes of Patients Hospitalized for Heart Failure in China: Results from the China Heart Failure (China-HF) Registry. Journal of Cardiac Failure, 23, 868-875. [Google Scholar] [CrossRef] [PubMed]
[6] Mcdonagh, T.A., Metra, M., Adamo, M., et al. (2021) 2021 ESC Guidelines for the Diagnosis and Treatment of Acute and Chronic Heart Failure. European Heart Journal, 42, 3599-3726.
[7] 李爱玲, 王万庆, 许永梅. 慢性充血性心力衰竭患者血清CA125、cTnT和BNP水平变化及临床诊断意义[J]. 国际医药卫生导报, 2018, 24(23): 3569-3572.
[8] Belknap, R.W. (2019) Current Medical Man-agement of Pulmonary Tuberculosis. Thoracic Surgery Clinics, 29, 27-35. [Google Scholar] [CrossRef] [PubMed]
[9] Perez, B.H. and Gipson, I.K. (2008) Focus on Molecules: Human Mucin MUC16. Thoracic Surgery Clinics, 87, 400-401. [Google Scholar] [CrossRef] [PubMed]
[10] Bast Jr., R.C., Feeney, M., Lazarus, H., et al. (1981) Reactivity of a Monoclonal Antibody with Human Ovarian Carcinoma. Journal of Clinical Investigation, 68, 1331-1337. [Google Scholar] [CrossRef] 
[11] Sikaris, K.A. (2011) CA125—A Test with a Change of Heart. Heart, Lung and Circulation, 20, 634-640. [Google Scholar] [CrossRef] [PubMed]
[12] Turgut, O., tandogan, L., Yilmaz, M.B., et al. (2011) CA125 in Heart Failure: Implications for Immunoinflammatoty Activity. International Journal of Cardiology, 146, 99-100. [Google Scholar] [CrossRef] [PubMed]
[13] Huang, F., Chen, J., Liu, Y., et al. (2012) New Mechanism of Elevated CA125 in Heart Failure: The Mechanical Stress and Inflammatory Stimuli Initiate CA125 Synthesis. Medical Hypotheses, 79, 381-383. [Google Scholar] [CrossRef] [PubMed]
[14] 赵龙, 张惠卿, 王前, 等. STMN1及UBE2C在胃癌组织中的表达及其临床意义[J]. 现代肿瘤医学, 2021, 29(7): 1187-1191
[15] 贺玲玲. 肝细胞癌中UBE2C及STMN1的表达及意义[D]: [硕士学位论文]. 承德: 承德医学院, 2021.
[16] Frump, A.L., Bonnet, S., De Jesus, P.V., et al. (2018) The Emerging Role of Angiogenesis in Adaptive and Maladaptive Right Ventricular Remodeling in Pulmonary Hyper-tension. American Journal of Physiology-Lung Cellular and Molecular Physiology, 314, L443-L460. [Google Scholar] [CrossRef] [PubMed]
[17] Nagele, H., Bahlo, M., Klapdor, R., et al. (1999) CA125 and Its Relation to Cardiac Function. American Heart Journal, 137, 1044-1049. [Google Scholar] [CrossRef] 
[18] Faggiano, P., D’Aloia, A., Brentana, L., et al. (2005) Serum Levels of Different Tumour Markers in Patients with Chronic Heart Failure. European Journal of Heart Failure, 7, 57-61. [Google Scholar] [CrossRef] [PubMed]
[19] Kosar, F., Aksoy, Y., Ozguntekin, G., et al. (2006) Rela-tionship between Cytokines and Tumour Markers in Patients with Chronic Heart Failure. European Journal of Heart Failure, 8, 270-274. [Google Scholar] [CrossRef] [PubMed]
[20] Kokilambigai, K.S., Lakshmi, K.S., Sai Susmitha, A., et al. (2020) Linezolid—A Review of Analytical Methods in Pharmaceuticals and Biological Matrices. Critical Reviews in Analytical Chemistry, 50, 179-188. [Google Scholar] [CrossRef] [PubMed]
[21] Huang, F., Chen, J., Liu, Y., et al. (2012) New Mechanism of Elevated CA125 in Heart Failure: The Mechanical Stress and Inflammatory Stimuli Initiate CA125 Synthesis. Medical Hypotheses, 79, 381-383. [Google Scholar] [CrossRef] [PubMed]
[22] Faggiano, P., D’aloia, A., Brentana, L., et al. (2014) Serum Levels of Different Tumour Markers in Patients with Chronic Heart Failure. European Journal of Heart Failure, 7, 57-61. [Google Scholar] [CrossRef] [PubMed]
[23] 陈琳. 急性心肌梗死(AMI)患者CA125 水平与心功能状态之间的关系分析[J]. 智慧健康, 2020, 6(2): 14-15.
[24] 邢国庆. 血清HSP27 CA125UA水平变化与老年慢性心力衰竭患者心功能的关联性[J]. 内蒙古医学杂志, 2020, 52(3): 318-319.
[25] Espriella, R., Miana, G., Santas, E., et al. (2021) Effects of Empagliflozin on CA125 Trajectory in Patients with Chronic Congestive Heart Failure. International Journal of Cardiology, 7, 521-522. [Google Scholar] [CrossRef] [PubMed]
[26] 马锦玲, 刘宏伟, 程友琴. 影响老年充血性心力衰竭患者血清CA125的相关因素分析[J]. 中国综合临床, 2011, 27(3): 252-255.
[27] Ming, Z., Shenwen, F.U., Aixia, L., et al. (2016) The Relationship between CA125 Levelsand Inflammatory Cytokines in Patients with Chronic Heart Failure. Journal of Electrocardiology, 2, 889-892.
[28] Stanciu, A.E., Stanciu, M.M. and Vatasescu, R.G. (2018) NT-proBNP and CA125 Levels Are Associated with Increased Pro-Inflammatory Cytokines in Coronary Sinus Serum of Patients with Chronic Heart Failure. Cytokines, 111, 13-19. [Google Scholar] [CrossRef] [PubMed]
[29] 张贤, 齐祥, 董忻悦, 等. 小肠细菌过度生长与慢性心力衰竭患者心功能的关系[J]. 江苏大学学报(医学版), 2021, 31(3): 251-256, 276.
[30] Rong, X., Yunke, Z., Guoping, L. and Zhenyue, C. (2015) Clinical and Prognostic Value of Ele-vated CA125 Levels in Patients with Coronary Heart Disease. Herz, 40, 690-694. [Google Scholar] [CrossRef] [PubMed]
[31] Yilmaz, H., Gürel, O.M., Celik, H.T., et al. (2014) CA 125 Levels and Left Ventricular Function in Patients with End-Stage Renal Disease on Maintenance Hemodialysis. Renal Failure, 36, 210-216. [Google Scholar] [CrossRef] 
[32] Hung, C.L., Hung, T.C., Liu, C.C., et al. (2012) Relation of Carbohydrate Antigen-125 to Left Atrial Remodeling and Its Prognostic Usefulness in Patients with Heart Failure and Preserved Left Ventricular Ejection Fraction in Women. The American Journal of Cardiology, 110, 993-1000. [Google Scholar] [CrossRef] [PubMed]
[33] Mansour, I.N., Napan, S., Tarek Alahdab, M., et al. (2010) Carbohydrate Antigen 125 Predicts Long-Term Mortality in African American Patients with Acute Decompensated Heart Failure. Congestive Heart Failure, 16, 15-20. [Google Scholar] [CrossRef] [PubMed]
[34] Ordu, S., Ozhan, H., Alemdar, R., et al. (2012) Carbohy-drate Antigen-125 and N—Terminal Pro-Brain Natriuretic Peptide Levels: Compared in Heart Failure Prognostication. Texas Heart Institute Journal, 39, 30-35.
[35] Antonini-Canterin, F., Popescu, B.A., Popescu, A.C., et al. (2008) Heart Failure in Patients with Aortic Stenosis: Clinical and Prognostic Significance of Carbohydrate Antigen 125 and Brain Natriuretic Peptide Measurement. International Journal of Cardiology, 128, 406-412. [Google Scholar] [CrossRef] [PubMed]
[36] Bulska-Bdkowska, W., Chemecka, E., Owczarek, A.J., et al. (2019) CA125 as a Marker of Heart Failure in the Older Women: Population-Based Analysis. Journal of Clinical Medi-cine, 8, Article 607. [Google Scholar] [CrossRef] [PubMed]
[37] 张胜豪, 刘恒亮, 毛磊, 等. 血清糖类抗原125及脑钠肽水平对心肌梗死后心力衰竭发生及严重程度的预测价值[J]. 中国动脉硬化杂志, 2019, 27(1): 55-60.

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