不同主诉干眼症患者与其眼表状态及泪液成分的相关性分析研究
Analysis of Correlation between Ocular Surface Status and Tear Composition in Patients with Different Complaints of Dry Eye
DOI: 10.12677/ACM.2024.143796, PDF,   
作者: 王 佩, 阎晓然*：青岛大学附属青岛市立医院眼科中心，山东 青岛；原江水：青岛大学附属青岛市立医院检验中心，山东 青岛
关键词: 泪液成分；干眼症；主诉症状；电解质；Tear Components； Dry Eye Syndrome； Chief Complaint； Electrolytes
摘要: 目的：观察不同主诉症状的干眼症患者与其眼表状态及泪液成分的相关性研究。方法：选取2023年5月~2023年10月于青岛市市立医院眼科中心门诊就诊患者78例，其中男21例(42只眼)；女57例(114只眼)。填写调查问卷，行眼表综合分析仪及泪液分泌试验检查，并对泪液部分成分进行检测。结果：1) 主诉症状前三位为：干涩、视疲劳、异物感。2) 症状累计评分与非侵入性泪膜破裂时间(NIKBUT)呈负相关，与睑板腺评分呈正相关，与白蛋白含量呈负相关。3) 视疲劳、灼热痛感、视力波动与NIKBUT呈负相关；干涩、视疲劳、异物感、灼热痛感、黏稠分泌物与睑板腺评分呈正相关。4) 视疲劳、眼痒与泪液白蛋白含量呈负相关。结论：干眼症患者不同主诉症状与其眼表状态及泪液成分具有一定的相关性。
Abstract: Objective: To observe the correlation between dry eye patients with different symptoms and their ocular surface status and tear composition. Methods: A total of 78 patients were selected from the outpatient department of the Ophthalmic Center of Qingdao Municipal Hospital from May 2023 to October 2023, including 21 males (42 eyes) and 57 females (114 eyes). The patients with dry eye were selected to fill in the questionnaire, and the comprehensive analysis of ocular surface and Schimer I test (SIT) were performed, and partial components of tear were detected. Results: 1) The top three symptoms of the chief complaint are: dryness, visual fatigue, foreign body sensation. 2) The cumulative score of dry eye symptoms was negatively correlated with non-invasive Kertograph break-up time (NIKBUT), positively correlated with meibomian gland score and negatively corre-lated with tear albumin content. 3) Visual fatigue, burning pain and visual fluctuation were nega-tively correlated with NIKBUT. Dryness, visual fatigue, foreign body sensation, burning pain and sticky secretions were positively correlated with meibomian gland score. 4) Visual fatigue and eye itching were negatively correlated with tear albumin content. Conclusion: There is a certain corre-lation between the different symptoms reported by patients with dry eye syndromes and their ocu-lar surface status and tear composition.
文章引用：王佩, 原江水, 阎晓然. 不同主诉干眼症患者与其眼表状态及泪液成分的相关性分析研究[J]. 临床医学进展, 2024, 14(3): 954-962. https://doi.org/10.12677/ACM.2024.143796

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