半夏泻心汤加减治疗儿童单纯性肥胖胃强脾弱型的临床研究

Clinical Study of Banxia Xiexin Decoction in the Treatment of Simple Obesity in Children with Strong Stomach and Weak Spleen

摘要: 目的：观察比较半夏泻心汤加减方治疗儿童单纯性肥胖胃强脾弱型的临床疗效。方法：选取60例胃强脾弱型单纯性肥胖患儿，按照随机数字表法分为观察组和对照组，每组各30例，观察组给予半夏泻心汤加减联合运动行为矫正基础疗法，对照组仅给予基础治疗，以2个月为一疗程，每组均治疗2个疗程。观察两组患儿治疗前后的体质量指数(body mass inex, BMI)，中医证候积分。结果：观察组与对照组治疗后BMI均显著降低(P < 0.01)；与对照组比较，在治疗后观察组BMI水平明显降低(P < 0.05)，与本组治疗前比较，两组患儿中医证候总积分均显著下降(P < 0.01)。治疗后与对照组比较，观察组的中医证候总积分更低(P < 0.01)。治疗后，观察组患儿治疗总有效率为90.00% (27/30)，对照组患儿治疗总有效率为70.00% (21/30)，经秩和检验比较，观察组总有效率优于对照组(Z = −1.975, P < 0.05)。结论：半夏泻心汤加减联合基础治疗对胃强脾弱型肥胖患儿临床疗效颇佳，能够明显降低肥胖患儿的体质量、BMI指数，改善患儿中医证候。

Abstract: Objective: To observe and compare the clinical efficacy of Banxia Xiexin Decoction in the treatment of simple obesity in children with stomach strong and spleen weak type. Methods: 60 children with simple obesity, stomach strength and spleen weakness were selected and divided into observation group and control group according to random number table method, with 30 cases in each group. The observation group was given Banxia Xiexin Decoction combined with exercise behavior correc-tion basic therapy, while the control group was given basic treatment only, with a course of 2 months. Each group was treated for 2 courses of treatment. Body mass index (BMI) and TCM syn-drome accumulation were observed before and after treatment. Results: BMI of observation group and control group was significantly decreased after treatment (P < 0.01). Compared with the control group, the BMI level in the observation group was significantly decreased after treatment (P < 0.05), and the total score of TCM syndrome in both groups was significantly decreased compared with that before treatment (P < 0.01). After treatment, the total score of TCM syndrome in the observation group was lower than that in the control group (P < 0.01). After treatment, the total effective rate was 90.00% (27/30) in the observation group and 70.00% (21/30) in the control group. By com-parison of rank sum test, the total effective rate in the observation group was better than that in the control group (Z = −1.975, P < 0.05). Conclusion: Banxia Xiexin Decoction combined with basic treatment has a good clinical effect on obese children with strong stomach and weak spleen, can significantly reduce the body mass and BMI index of obese children, and improve the TCM syn-drome of children.