线粒体未折叠蛋白反应及其在部分恶性肿瘤中的研究进展
Mitochondrial Unfolded Protein Response and Its Research Progress in Some Malignant Tumors
DOI: 10.12677/ACM.2024.143814, PDF,    科研立项经费支持
作者: 王延呈, 马绍云, 宁 晨*：贵德县人民医院内一科，青海 贵德
关键词: 线粒体未折叠蛋白反应；恶性肿瘤；综述；UPRmt； Malignant Tumors； Review
摘要: 线粒体未折叠蛋白反应(mitochondrial unfolded protein response, UPRmt)是线粒体应激反应的标志之一，研究发现它参与了许多病理生理过程，但关于UPRmt和恶性肿瘤关系的研究目前相对较少。本文就UPRmt的调节机制以及它在前列腺癌、乳腺癌、肺癌及胃癌中的研究进展做一综述。
Abstract: Mitochondrial unfolded protein response (UPRmt), one of the hallmarks of mitochondrial stress re-sponse, has been found to be involved in many pathophysiological processes, but relatively little research has been done on the relationship between UPRmt and malignancies. This article reviews the regulatory mechanisms for UPRmt and the research advances in UPRmt in prostate cancer, breast cancer, lung cancer and gastric cancer.
文章引用：王延呈, 马绍云, 宁晨. 线粒体未折叠蛋白反应及其在部分恶性肿瘤中的研究进展[J]. 临床医学进展, 2024, 14(3): 1091-1096. https://doi.org/10.12677/ACM.2024.143814

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