阑尾杯状细胞腺癌1例并文献复习

A Case Report of Goblet Cell Adenocarcinoma and Literature Review

摘要: 目的：提高临床医师对阑尾杯状细胞腺癌的认识、诊断及治疗。方法：回顾分析2023年12月青岛市市立医院收治的1例阑尾杯状细胞腺癌的临床资料，并复习相关文献。结果：患者为73岁老年女性，以“慢性阑尾炎”收入院，行腹腔镜下阑尾切除术，术后病理提示为杯状细胞腺癌。后行腹腔镜右半结肠切除术，术后病理未见肿瘤组织残余及其他脏器转移，结合病理、免疫组化及PET-CT，未行化疗，术后恢复良好后出院。结论：阑尾杯状细胞腺癌为隐匿性较高的恶性肿瘤，手术是其主要治疗方式。研究分析GCA的诊断和治疗，对推进其规范化治疗有深刻意义。

Abstract: Objective: To enhance the comprehension, differential diagnosis, and treatment of goblet cell adenocarcinoma (GCA) of the appendix. Methods: The clinical data of a case involving GCA of the appendix admitted to Qingdao Municipal Hospital in December 2023 were retrospectively analyzed, and relevant literature was reviewed. Results: The patient, a 73-year-old woman with chronic appendicitis symptoms, underwent laparoscopic appendectomy followed by laparoscopic right hemicolectomy. Postoperative pathology revealed no residual tumor tissue or metastasis to other organs. Based on the results from pathology, immunohistochemistry, and PET-CT scans, chemotherapy was not administered to the patient who recovered well after surgery and was discharged. Conclusions: Goblet cell adenocarcinoma of the appendix (GCA) is an extremely insidious malignant tumor with symptoms and signs that often mimic acute appendicitis. Surgical intervention constitutes the primary treatment for GCA patients. In addition to appendectomy, right hemicolectomy is also necessary upon diagnosing GCA. The study and analysis of GCA diagnosis and treatment hold profound significance in further advancing standardized care for affected individuals.