新型冠状病毒感染与睡眠障碍关系研究进展

Research Progress on the Relationship between Novel Coronavirus Infection and Sleep Disorder

摘要: 新型冠状病毒肺炎是由严重急性呼吸综合征冠状病毒2 (SARS-CoV-2)感染引起的一种新的高传染性疾病，2019年底出现，引发全球大流行。临床观察发现，部分新冠患者发病后数月仍未完全恢复，出现咳嗽、胸闷、气短、嗅觉、味觉减退、疲劳、失眠、焦虑、抑郁等症状，即长新冠综合征。其中睡眠障碍非常常见，且对于感染后人群的工作、生活及心理造成了很大困扰，但其发病机制尚不清楚，因此很有必要进行探究。本文对新型冠状病毒感染引起睡眠障碍的可能机制进行综述，以利于更深入地了解长新冠的发病机制、预警信号、早期干预措施，从而提出更好的治疗方案。

Abstract: COVID-19 is a new highly infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, which emerged in late 2019, triggering a global pandemic. Clinical observations have found that some COVID-19 patients still have not fully recovered after several months of onset, and they have symptoms such as cough, chest tightness, shortness of breath, decreased sense of smell and taste, fatigue, insomnia, anxiety, and depression, namely long COVID-19 syndrome. Among them, sleep disorder is very common, and it causes great distress to the work, life, and psychology of the infected population. However, its pathogenesis is still unclear, so it is necessary to explore. This article reviews the possible mechanisms of sleep disorder caused by novel coronavirus infection, in order to better understand the pathogenesis, warning signals, and early intervention measures of COVID-19, so as to put forward better treatment plans.